| UK Online Safety Training Ltd | Education | 2014 |
| UK Pizza (Jarrow) Ltd | Hospitality | 2018 |
| UK Pizza L Ltd | Hospitality | 2024 |
| UK Pizza M Ltd | Hospitality | 2025 |
| UK Pizza NE32 Ltd | Hospitality | 2025 |
| UK Site Cladding Services Ltd | Construction | 2019 |
| Ukasl Ltd | Extraterritorial | 2010 |
| Ulrich Attachments Limited | Manufacturing | 1998 |
| Ultimate Risk Management Limited | Construction | 2006 |
| Umbrella PT Training Ltd | Education | 2020 |
| Underpressure Pipeline Solutions Limited | Manufacturing | 2005 |
| Universal Scaffolding North East Ltd | Construction | 2021 |
| Uptons Vape Store Jarrow Ltd | Wholesale & retail | 2023 |
| Urban Bedrooms Limited | Construction | 2014 |
| Urbane Bloke Story Ltd | Information & communication | 2025 |
| Usertivity Limited | Information & communication | 2024 |
| Utility First Ltd | Water & waste | 2021 |
| UTS Engineering Limited | Manufacturing | 2001 |
| Valkyrie MEP Consulting Engineers Ltd | Professional & scientific | 2019 |
| Valley View Joinery & Building Ltd | Construction | 2026 |
| Valuetop Limited | Real estate | 2025 |
| Vantage Supplies Ltd | Wholesale & retail | 2023 |
| Ventilation Services North East Limited | Manufacturing | 2021 |
| Veterans Response C.I.C. | Other services | 2013 |
| Viking Asbestos Removal Specialists Limited | Construction | 2023 |
| Village Tandoori (Jarrow) Limited | Hospitality | 2019 |
| Vinyl Gogo Ltd | Arts & recreation | 2026 |
| Vitalis NE Limited | Construction | 2017 |
| Vortex Fire and Security Solutions Ltd | Administrative & support | 2025 |
| W Leyden Building Services Limited | Construction | 2026 |
| Wake's Walls Ltd | Construction | 2021 |
| Ward W Ltd | Hospitality | 2026 |
| Washarms Ltd | Hospitality | 2025 |
| Waskerley Freehold Ltd | Real estate | 2020 |
| Wearpoint Ltd | Professional & scientific | 2026 |
| Webber Meter Services Limited | Manufacturing | 2015 |
| What Happens Next NCL CIC | Arts & recreation | 2026 |
| Whitburn Steel Licensed Restaurant Ltd | Hospitality | 2020 |
| White Renewables Limited | Professional & scientific | 2023 |
| Whitehouse Property Management Ltd | Real estate | 2020 |
| Wilkinson Property Rentals Ltd | Real estate | 2022 |
| Wilkinstock Properties Limited | Real estate | 2021 |
| Williby Roc's Community Interest Company | Arts & recreation | 2018 |
| Winchester Development Property Limited | Wholesale & retail | 2004 |
| Windmech Technical Services Ltd | Extraterritorial | 2023 |
| Wine on the Tyne Ltd | Manufacturing | 2025 |
| Wisetype Limited | Hospitality | 2001 |
| WRG Energy Ltd | Professional & scientific | 2023 |
| Xmas Properties Ltd | Real estate | 2020 |
| XRP Ltd | Hospitality | 2026 |
| YIN & Co Trading Ltd | Wholesale & retail | 2025 |
| Ynot Studios Ltd | Administrative & support | 2024 |
| Your Property Angels Ltd | Real estate | 2024 |
| Your Vans Group Ltd | Transport & logistics | 2026 |
| YS Clinical Plus Ltd | Health & social care | 2025 |
| Z & K Handyman and Cleaning Ltd | Construction | 2023 |
| Zana Cater Limited | Hospitality | 2025 |
| Zeera Indian Cuisine (South Shields) Ltd | Hospitality | 2016 |
| Zetec Digital Limited | Information & communication | 2026 |
| Zeynap Ltd | Other services | 2020 |
| ZG Holdings Ltd | Real estate | 2023 |
| Zskp Investments Limited | Real estate | 2026 |
| £99 Carpet Factory Ltd | Wholesale & retail | 2020 |