| Dream Hair Hull Limited | Other services | 2019 |
| Dream Home Improvements (Yorkshire) Ltd | Construction | 2016 |
| Dream Nails 257 Ltd | Other services | 2026 |
| Dream Wigs by Tanya Ltd | Arts & recreation | 2025 |
| Dreamcatcherhull Ltd | Hospitality | 2025 |
| Dreamscience Automotive (Holdings) Ltd | Administrative & support | 2024 |
| Dreamscience Automotive Limited | Wholesale & retail | 2005 |
| Dreamtimez Bedz Limited | Wholesale & retail | 2019 |
| Dren Electrical Ltd | Energy | 2016 |
| Drewery Electrical Limited | Construction | 2016 |
| Drezaliu Driving Ltd | Transport & logistics | 2019 |
| DRF Digital Ltd | Professional & scientific | 2025 |
| DRG Enterprise Limited | Construction | 2023 |
| DRH24 Limited | Information & communication | 2024 |
| Driffield Car Wash Limited | Other services | 2021 |
| Driffield Rufc Limited | Arts & recreation | 2016 |
| Driffield Rufc Trading Limited | Hospitality | 2015 |
| Drilling Expert Legal Services Limited | Mining & quarrying | 2014 |
| Drinial Property Limited | Real estate | 2024 |
| Driveline Vehicle Delivery Hull Ltd | Transport & logistics | 2019 |
| Driver Call Support Services Limited | Transport & logistics | 2025 |
| Driver for Cover Limited | Transport & logistics | 2015 |
| Drmoyeb Global Services Ltd | Construction | 2025 |
| Drogers Developments Ltd | Construction | 2021 |
| Dromtariffe Ltd | Information & communication | 2014 |
| Droppoint C.I.C. | Information & communication | 2017 |
| DRS MAX Racing Ltd | Wholesale & retail | 2021 |
| DRT Hire Ltd | Administrative & support | 2017 |
| Druidcoffee Ltd | Hospitality | 2025 |
| Dryden Line Markings Limited | Other services | 2002 |
| Drypool Freight Services Limited | Transport & logistics | 1994 |
| Drypool Limited | Real estate | 2020 |
| Drypool MOT and Repair Centre Ltd | Wholesale & retail | 2013 |
| Drypool Plant Limited | Administrative & support | 1982 |
| Dryrock Limited | Real estate | 2002 |
| DS BAL Ltd | Real estate | 2020 |
| DS Driving Services Limited | Transport & logistics | 2012 |
| DS Meals Ltd | Hospitality | 2026 |
| DS Subsea Inspection Ltd | Professional & scientific | 2014 |
| DSA Property Ltd | Real estate | 2022 |
| DSC Building Services Ltd | Construction | 2013 |
| DSD Group Limited | Construction | 2016 |
| Dshredx Ltd | Arts & recreation | 2026 |
| Dsjd Limited | Real estate | 2020 |
| Dsmt Building Solutions Ltd | Extraterritorial | 2025 |
| DSU Services Limited | Construction | 2025 |
| Dszn Ltd | Professional & scientific | 2022 |
| DT Vintage Limited | Wholesale & retail | 2018 |
| DTM Enterprises Limited | Hospitality | 2015 |
| DUA Cleaning Services Ltd | Administrative & support | 2025 |
| Dual GAS Services Limited | Construction | 2008 |
| Dualcoat Property Solutions Limited | Construction | 2007 |
| Dubai Shisha Cafe Limited | Hospitality | 2018 |
| Dubai Vapes Ltd | Wholesale & retail | 2025 |
| Dubray Catering and Coffee Co Limited | Hospitality | 2018 |
| Dubs on the Coast Ltd | Administrative & support | 2022 |
| Duck Nest Properties Limited | Real estate | 2019 |
| Duffield Fish & Chips Limited | Extraterritorial | 2020 |
| Dukes Wharf (York) Freehold Limited | Households | 2022 |
| Dulian Property Ltd | Construction | 2013 |
| Duncan Rann Associates Limited | Professional & scientific | 2013 |
| Duncan Taylor Ltd | Wholesale & retail | 2017 |
| Duncans (Gunmakers) Limited | Wholesale & retail | 1946 |
| Dune Buggy International Ltd | Manufacturing | 2025 |
| Dunnwell Homes Ltd | Construction | 2021 |
| DUO Catering Limited | Hospitality | 2022 |
| DUO Joinery & Modular Services Ltd | Construction | 2022 |
| DUO Logistics Ltd | Transport & logistics | 2025 |
| Duo-Tech (Hull) Ltd | Construction | 2024 |
| Durable Doors Ltd | Wholesale & retail | 2024 |
| Duracare Products Europe Limited | Wholesale & retail | 2026 |
| Duracare Products Limited | Wholesale & retail | 2020 |
| Durango Drywall Ltd. | Construction | 2013 |
| Durham & Tees Community Ventures Fundco (NO.1) Limited | Construction | 2004 |
| Durham & Tees Community Ventures Fundco (NO.2) Limited | Construction | 2005 |
| Durham & Tees Community Ventures Fundco (NO.3) Limited | Construction | 2005 |
| Durham & Tees Community Ventures Fundco (NO.4) Limited | Construction | 2009 |
| Durham & Tees Community Ventures Holdco (NO.1) Limited | Professional & scientific | 2004 |
| Durham & Tees Community Ventures Holdco (NO.2) Limited | Professional & scientific | 2004 |
| Durham & Tees Community Ventures Holdco (NO.3) Limited | Professional & scientific | 2005 |
| Durham & Tees Community Ventures Holdco (NO.4) Limited | Professional & scientific | 2009 |
| Durham & Tees Community Ventures Limited | Professional & scientific | 2004 |
| Dushaj Events Limited | Hospitality | 2025 |
| Duskrose Limited | Households | 1979 |
| Dutch Therapy Ltd | Manufacturing | 2025 |
| Dutton Moore Limited | Professional & scientific | 2007 |
| Dvornik Company Limited | Health & social care | 2018 |
| DVS Car Sales Ltd | Wholesale & retail | 2025 |
| DW Bespoke Joinery Hull Ltd | Construction | 2021 |
| DW Electrical (Hull) Ltd | Construction | 2026 |
| DW Rail Safety Limited | Transport & logistics | 2016 |
| DW Roofing&Building Ltd | Construction | 2017 |
| DWALTON29 Ltd | Information & communication | 2025 |
| Dwannwind Ltd | Manufacturing | 2023 |
| Dwellux Apartments Ltd | Hospitality | 2025 |
| Dwhomes Ltd | Construction | 2026 |
| DWS Consultancy Services Limited | Administrative & support | 2007 |
| Dylan Pizza Ltd | Hospitality | 2019 |
| Dynac UK Limited | Manufacturing | 2011 |
| Dynamic Properties Group Ltd | Real estate | 2025 |