| Dkdl Limited | Transport & logistics | 2024 |
| DKL Services Ltd | Transport & logistics | 2022 |
| DKM Engineering Consultants Ltd | Professional & scientific | 2017 |
| DKM Medical Limited | Professional & scientific | 2020 |
| DKM Neurosurgery Limited | Real estate | 2024 |
| DKM Retail Limited | Wholesale & retail | 2022 |
| DLG and BJG Holdings Limited | Real estate | 2021 |
| DLG Flooring Limited | Construction | 2014 |
| Dlmg Limited | Construction | 2022 |
| DM DM 1 Market Ltd | Wholesale & retail | 2025 |
| DM DM Market Ltd | Wholesale & retail | 2025 |
| DM DM Mini Market 1 Ltd | Wholesale & retail | 2024 |
| DM East Ltd | Wholesale & retail | 2022 |
| DM Sales Solutions Ltd | Administrative & support | 2025 |
| DMA Leisure Holdings Limited | Financial services | 2023 |
| Dmbladerepair Ltd | Manufacturing | 2025 |
| DMC Yorkshire Investments Limited | Financial services | 2023 |
| DMD Global Ltd. | Professional & scientific | 2001 |
| DMK Consult Ltd | Professional & scientific | 2024 |
| DMK LET Limited | Real estate | 2024 |
| DMM Haulage Ltd | Transport & logistics | 2022 |
| DMO Sales Limited | Extraterritorial | 2025 |
| DMR Auto Centre Ltd | Wholesale & retail | 2022 |
| Dmvr Limited | Real estate | 2001 |
| DMW Business Consultancy Limited | Professional & scientific | 2024 |
| DN Electrical Solutions Ltd | Construction | 2022 |
| DNC Gemstones Collection and DRY Goods Ltd | Wholesale & retail | 2026 |
| DND Construct Ltd | Construction | 2024 |
| DNG Ventures Ltd | Wholesale & retail | 2023 |
| Dock Health Limited | Health & social care | 2024 |
| Dock Robotics Ltd. | Professional & scientific | 2021 |
| Dock Street Management Number 2 Ltd | Households | 2014 |
| Dodo Shop Ltd | Wholesale & retail | 2024 |
| Dodo's 1 Ltd | Wholesale & retail | 2025 |
| Dodos Lane Ltd | Wholesale & retail | 2025 |
| Doggy Dilemmas Canine Behaviour and Training Solutions Ltd | Other services | 2018 |
| Dolores Holdings Limited | Financial services | 2020 |
| Dolphin Car Wash (Greenwich) Limited | Other services | 2019 |
| DOM Wilson Design Limited | Arts & recreation | 2014 |
| Domapp Limited | Wholesale & retail | 2015 |
| Dominics Takeaway Limited | Hospitality | 2002 |
| Dominion City Hull | Other services | 2024 |
| Domisi Ltd | Real estate | 2025 |
| DON Sharpe Limited | Manufacturing | 1980 |
| Donaldson Filter Components Limited | Manufacturing | 1975 |
| Donaldson Filtration (GB) Limited | Manufacturing | 2000 |
| Donaldson UK Holding Limited | Professional & scientific | 2003 |
| Donaldsons Dairy Management Company Ltd | Households | 2008 |
| Donlina Limited | Real estate | 2025 |
| Donmi Catering Ltd | Manufacturing | 2025 |
| Dooks Property Limited | Real estate | 2021 |
| Door 2 Door Carpets & Vinyls Ltd | Wholesale & retail | 2019 |
| Door Key Limited | Hospitality | 2012 |
| Door Repair and Service Yorkshire Limited | Manufacturing | 2007 |
| Door@Theclub Limited | Hospitality | 2025 |
| Dope Burger Limited | Manufacturing | 2017 |
| Dopegraphics Ltd | Wholesale & retail | 2023 |
| Doraly Ltd | Health & social care | 2022 |
| Dossormca, Consulting Engineers and Surveyors Limited | Professional & scientific | 2013 |
| DOT 2 DOT Social Ltd | Professional & scientific | 2026 |
| Dotski Technology Ltd | Information & communication | 2019 |
| Dotx Impact Ltd | Information & communication | 2024 |
| Double BS (Hull) Limited | Hospitality | 2025 |
| Double Click Design Ltd | Information & communication | 2016 |
| Double O Interior Ltd | Construction | 2025 |
| Double Oak Ltd | Administrative & support | 2018 |
| Dough Box Ltd | Hospitality | 2025 |
| Dough PIE Limited | Hospitality | 2020 |
| Douglas James Limited | Manufacturing | 1999 |
| Douglas Livery Ltd | Agriculture & fishing | 2024 |
| Dove Care & Support Limited | Health & social care | 2025 |
| Dove House Hospice Limited | Education | 1980 |
| Dove White Living Ltd | Construction | 2026 |
| Dovedale Dampcure Services Ltd | Construction | 2014 |
| Dovyd Services Ltd | Construction | 2026 |
| Downs Fish Shop Limited | Hospitality | 2016 |
| DPF Repair Hull Ltd | Wholesale & retail | 2020 |
| Dpgi Investments Limited | Real estate | 2025 |
| DPS Inspections Limited | Professional & scientific | 2025 |
| DPT Electrical Ltd | Administrative & support | 2016 |
| DR & J Ground Services Ltd | Construction | 2020 |
| DR Business Limited | Wholesale & retail | 2025 |
| DR HTS Limited | Wholesale & retail | 2026 |
| DR Hypnotherapy Ltd | Health & social care | 2021 |
| DR James Britton Limited | Health & social care | 2015 |
| DR London Construction Ltd | Construction | 2022 |
| DR London Foods Ltd | Manufacturing | 2024 |
| DR Rigging @ Lifting Ltd | Construction | 2022 |
| DR Silva and Family Ltd | Health & social care | 2024 |
| DR T M Eckersley Limited | Health & social care | 2018 |
| Dr-B Property ENG Limited | Real estate | 2019 |
| Dr.Elena Marian Ltd | Professional & scientific | 2015 |
| DR4DR Ltd | Administrative & support | 2022 |
| Dragon Dagger Limited | Hospitality | 2024 |
| Dragon House Hull Ltd | Hospitality | 2025 |
| Drameh Property Limited | Real estate | 2022 |
| Draper Properties Limited | Real estate | 2019 |
| Drapers England Limited | Manufacturing | 2020 |
| Drapers Recycling Limited | Real estate | 2008 |
| Dream Garden Accessories Ltd | Manufacturing | 2021 |