| Eaton Gardens Properties Limited | Real estate | 2003 |
| Eaton Lodge (Hove) Limited | Households | 1994 |
| Eaton News Limited | Wholesale & retail | 2017 |
| Eaton Road Dental Practice Limited | Health & social care | 2007 |
| Eazy Bizzy Ltd | Wholesale & retail | 2022 |
| Eazy Sleeve Limited | Administrative & support | 2024 |
| EB Films Limited | Information & communication | 2010 |
| Ebnal Lodge Solar Project Limited | Energy | 2014 |
| EC Event Carpentry Limited | Manufacturing | 2022 |
| Ecclestone Ltd | Professional & scientific | 2009 |
| ECH SPV Limited | Financial services | 2024 |
| Echidna Ltd | Manufacturing | 2011 |
| Echo Kushu Ltd | Information & communication | 2025 |
| Echo Property Holdings Ltd | Real estate | 2025 |
| Echo RTM Company Limited | Extraterritorial | 2023 |
| Eckland Lodge Solar Limited | Energy | 2016 |
| Eco Builds South East Ltd | Construction | 2025 |
| Eco Skincare Ltd | Wholesale & retail | 2019 |
| Ecosphere Renewables Limited | Extraterritorial | 2023 |
| Ecotype Genetics Limited | Professional & scientific | 2018 |
| Ecousta Ltd | Manufacturing | 2026 |
| Eddie's Barbers Ltd | Administrative & support | 2017 |
| Eddy's Heights Limited | Hospitality | 2019 |
| Eden New Life Limited | Health & social care | 2023 |
| Eden Stretch Tents Limited | Administrative & support | 2018 |
| Edgar & Co UK Limited | Construction | 2019 |
| Edge Club CIC | Arts & recreation | 2024 |
| Edge of Possible Ltd | Professional & scientific | 2025 |
| Edgeforce Accountancy and Finance Limited | Professional & scientific | 2026 |
| Edible Creative Ltd | Professional & scientific | 2016 |
| Edit Design Ltd | Professional & scientific | 2019 |
| EDL GBR Ltd | Wholesale & retail | 2025 |
| EDN Accountants Limited | Professional & scientific | 2020 |
| Edokko Sounds Ltd | Information & communication | 2016 |
| EDR Heating Services Ltd | Construction | 2014 |
| Edukudu Ltd | Information & communication | 2014 |
| Edurespect School Ltd | Education | 2018 |
| Edward Bettison Limited | Administrative & support | 2009 |
| Edward Hession Limited | Arts & recreation | 2003 |
| Edwards Modular Control Limited | Manufacturing | 1977 |
| EE Dental Care Ltd | Health & social care | 2021 |
| Eediot Creative Technologies Ltd. | Information & communication | 2012 |
| Eeetwell UK Limited | Hospitality | 2021 |
| Efendi Ltd | Transport & logistics | 2021 |
| Effect Signal Ltd | Administrative & support | 2013 |
| EFS Enterprise Ltd | Administrative & support | 2025 |
| Eg-Uk Ltd | Education | 2019 |
| Ehfw Holdings Limited | Real estate | 2020 |
| Ehoapp Limited | Information & communication | 2026 |
| EIG Financial Ltd | Wholesale & retail | 2024 |
| Eight Dimensions Ltd | Professional & scientific | 2019 |
| Eight Langdale Road, Hove, Limited | Households | 1965 |
| Eisenberger Ltd | Health & social care | 2017 |
| EJ Parker Holdings Ltd | Construction | 2020 |
| EJC BSK Limited | Health & social care | 2023 |
| EK Bookkeeping Ltd | Professional & scientific | 2020 |
| EK Coast Limited | Real estate | 2023 |
| EL Alto Travel Group Ltd | Administrative & support | 2004 |
| EL Ardiente Ltd | Hospitality | 2026 |
| EL Methak Ltd | Wholesale & retail | 2025 |
| EL Moono Limited | Information & communication | 2021 |
| ELA Poole Limited | Other services | 2022 |
| Elastic Dance Ltd | Arts & recreation | 2025 |
| ELB Electrical Limited | Construction | 2013 |
| ELC Accounting Ltd | Education | 2015 |
| Eleanor Close Management Company Limited | Households | 1982 |
| Elearning Futures Ltd | Education | 2021 |
| Electronic Music Company Ltd | Information & communication | 2023 |
| Elegant Education UK Ltd | Education | 2017 |
| Elek LO Limited | Arts & recreation | 2025 |
| Element Search LLP | | 2013 |
| Elemental Resolve Ltd | Professional & scientific | 2025 |
| Elements Build UK Ltd | Construction | 2018 |
| Elements Haywards Heath Limited | Arts & recreation | 2023 |
| Elementuv Ltd | Professional & scientific | 2017 |
| Elena Essex Trading Limited | Professional & scientific | 2021 |
| Elevate Tuition Group Ltd | Education | 2026 |
| Elevated Youth Ltd | Professional & scientific | 2017 |
| Eleven Eaton Place Flat Management Company Limited | Households | 2000 |
| ELEVEN11 Digital Limited | Professional & scientific | 2015 |
| ELG Asset Management Limited | Financial services | 2009 |
| Elif Communications Ltd | Information & communication | 2022 |
| Elite Construction & Consulting Ltd | Construction | 2022 |
| Elite Edge Fitness Ltd | Arts & recreation | 2023 |
| Elite Gainz Ltd | Wholesale & retail | 2019 |
| Elite LB Limited | Construction | 2023 |
| Elite LT Ltd | Construction | 2010 |
| Elite Medicals and Equipments Limited | Health & social care | 2013 |
| Elite Travel Management Ltd. | Administrative & support | 2014 |
| Elite Tutoring Services Limited | Education | 2016 |
| Elite Tutors Sussex Ltd | Education | 2019 |
| Elizayn Properties Ltd | Real estate | 2017 |
| Elka Prints Ltd | Wholesale & retail | 2024 |
| Elko Representation Limited | Professional & scientific | 2011 |
| Ellie Lustig Limited | Administrative & support | 2011 |
| Ellis Bates Financial Solutions Limited | Financial services | 1982 |
| Ellis Bates Group Ltd. | Financial services | 2014 |
| Ellis Bates Legal Solutions Ltd | Professional & scientific | 2015 |
| Ellis Bates Wealth Management Ltd | Financial services | 2014 |
| Ellis Property Partnership Ltd | Real estate | 2022 |