| SEO & Review Services Limited | Professional & scientific | 2025 |
| SEO Web 365 Ltd | Information & communication | 2025 |
| Sepp Interiors Limited | Manufacturing | 2019 |
| Sequre Technologies UK Ltd | Information & communication | 2023 |
| Serage U.K. Limited | Wholesale & retail | 2014 |
| Seren Maison Limited | Wholesale & retail | 2026 |
| Serena Enterprise Limited | Wholesale & retail | 2021 |
| Serena Ventures Limited | Wholesale & retail | 2025 |
| Serendip Fish Hunters Ltd | Wholesale & retail | 2026 |
| Sergo Group Ltd | Construction | 2018 |
| Serious About Business Enterprises Ltd | Construction | 2018 |
| Serious Savings Limited | Administrative & support | 2016 |
| Service Project Ltd | Construction | 2014 |
| Services Forever Limited | Information & communication | 2025 |
| Sesha Business Services Limited | Information & communication | 2015 |
| Sethi & Sons Investments Ltd | Real estate | 2026 |
| Sethi Commercial Limited | Real estate | 2025 |
| Sethi Investment PVT Ltd | Real estate | 2022 |
| Seven Stars Motors Ltd | Professional & scientific | 2009 |
| Seventh Gateway Ltd | Professional & scientific | 2024 |
| Seventh Heaven Corporation Ltd | Financial services | 2021 |
| Seventhheavenstore Ltd | Extraterritorial | 2021 |
| Seymours Gardens Limited | Real estate | 1982 |
| SF WM UK Limited | Transport & logistics | 2025 |
| Sfida | Professional & scientific | 2009 |
| SFW Logistics Limited | Transport & logistics | 2020 |
| SG Food & Wine Ltd | Wholesale & retail | 2024 |
| SG Global Solutions Limited | Information & communication | 2024 |
| SG Intl Ltd | Wholesale & retail | 2026 |
| SG Resi Ltd | Real estate | 2018 |
| SG U.K Ltd | Wholesale & retail | 2025 |
| SG1 Estates Ltd | Real estate | 2025 |
| SGA Haulage Ltd | Transport & logistics | 2024 |
| SGK Group Ltd | Wholesale & retail | 2019 |
| SGS Developers Limited | Construction | 2021 |
| SH Buildings Ltd | Construction | 2022 |
| SHA Structures Ltd | Construction | 2022 |
| Sha-Ark Technologies Ltd | Professional & scientific | 2019 |
| Shaar Limited | Wholesale & retail | 2025 |
| Shaark Properties Ltd | Real estate | 2025 |
| Shabnam Ltd | Professional & scientific | 2024 |
| Shachou Group Limited | Wholesale & retail | 2024 |
| Shackleton Beacon LLP | | 2023 |
| Shades Beauty UK Ltd | Wholesale & retail | 2022 |
| Shah G Digital Ltd | Wholesale & retail | 2025 |
| Shah Wellbeing Ltd | Health & social care | 2016 |
| Shahab Traders Ltd | Wholesale & retail | 2022 |
| Shahana Ecom Limited | Wholesale & retail | 2026 |
| Shaheen Hub Ltd | Wholesale & retail | 2026 |
| Shahual Logistic Ltd | Wholesale & retail | 2026 |
| Shaikho Ltd | Wholesale & retail | 2026 |
| Shaivites Ltd | Financial services | 2002 |
| Shakahar Motors Ltd | Wholesale & retail | 2026 |
| Shaker Style Ltd | Manufacturing | 2026 |
| Shakespeare Security Ltd | Administrative & support | 2019 |
| Shaki Automotive Limited | Wholesale & retail | 2025 |
| Shaleena Nowbuth Ltd | Professional & scientific | 2017 |
| Shalom Telugu Christian Fellowship London Ltd. | Information & communication | 2021 |
| Sham Realty Limited | Real estate | 2026 |
| Shambu Properties Ltd | Real estate | 2023 |
| Shamoon Holdings Ltd | Financial services | 2020 |
| Shamoon Investments Limited | Real estate | 2016 |
| Shamoon Limited | Health & social care | 2012 |
| Shan E-Solutions Limited | Information & communication | 2010 |
| Shan Global IT Solutions Limited | Administrative & support | 2013 |
| Shan International Limited | Transport & logistics | 2025 |
| Shan J Construction Ltd | Construction | 2017 |
| Shanbiz Limited | Wholesale & retail | 2020 |
| Shanti Constructions Ltd | Construction | 2024 |
| Shanti Real Estate Holdings Ltd | Real estate | 2025 |
| Shapra Ltd | Hospitality | 2024 |
| Sharadamba Consulting Services Limited | Information & communication | 2024 |
| Sharanya Solutions Limited | Information & communication | 2012 |
| Shardz Ltd | Other services | 2025 |
| Shariff Transport Limited | Transport & logistics | 2023 |
| Shariff's Kitchen Ltd | Hospitality | 2025 |
| Shark EYE Ltd | Wholesale & retail | 2019 |
| Shark Investments (R K) Limited | Real estate | 2017 |
| Sharma Property Limited | Real estate | 2024 |
| Sharmapharma Ltd | Health & social care | 2016 |
| Sharp Book House Ltd | Wholesale & retail | 2023 |
| Sharp Fadez Barbershop Ltd | Other services | 2023 |
| Sharry Crown Roofing Ltd | Construction | 2025 |
| Shaso Consultancy Ltd | Professional & scientific | 2015 |
| Shavington Local Ltd | Wholesale & retail | 2025 |
| Shaw & Co. Estate Agents Limited | Real estate | 2011 |
| Shawarbi & Associates Limited | Professional & scientific | 2023 |
| Shawarma Bitess Ltd | Hospitality | 2025 |
| Shawarma Box Ltd. | Hospitality | 2015 |
| Shay and Co Trading Ltd | Wholesale & retail | 2025 |
| Shaypes Ltd | Other services | 2016 |
| Shazaah London Limited | Wholesale & retail | 2018 |
| Shazee UK Ltd | Professional & scientific | 2018 |
| Shazim Star Limited | Hospitality | 2025 |
| Shazm Properties Limited | Real estate | 2023 |
| Shazz Traders Ltd | Wholesale & retail | 2022 |
| Shcon Ltd | Construction | 2025 |
| Shedambi Lettings Ltd | Real estate | 2021 |
| Shedambi Limited | Information & communication | 2012 |
| Sheikh Bilal UK Retail Limited | Wholesale & retail | 2026 |