| Sheikh Property Services Limited | Construction | 2015 |
| Sheikh&A Ltd | Financial services | 2023 |
| Sheja Food & Wine Limited | Wholesale & retail | 2025 |
| Shekar Property Holdings Limited | Real estate | 2019 |
| Shelburne Drive Residents Company Limited | Households | 1999 |
| Shelburne END Management Company Limited | Households | 2016 |
| Shellbourne Consultin Limited | Administrative & support | 2026 |
| Shelley Close Langley Ltd | Real estate | 2025 |
| Sheltering Hands Care Ltd | Health & social care | 2022 |
| Shelysa Ltd | Wholesale & retail | 2025 |
| Shems Properties Ltd | Real estate | 2022 |
| Sheoran Transport Limited | Transport & logistics | 2025 |
| Sher Magic UK Limited | Wholesale & retail | 2026 |
| Shere Punjab House Limited | Real estate | 2026 |
| Sheryy Ltd | Construction | 2023 |
| Shetson Property Developments Limited | Construction | 1993 |
| Sheya Flowers Ltd | Wholesale & retail | 2020 |
| Shifa Fleet Services Limited | Information & communication | 2022 |
| Shifa Shangrila Ltd | Wholesale & retail | 2025 |
| Shilajit Shot Limited | Manufacturing | 2023 |
| Shilohpraise Estates Limited | Real estate | 2024 |
| Shine & Drive Ltd | Administrative & support | 2025 |
| Shine Mantainence Ltd | Administrative & support | 2025 |
| Shine Training Ltd | Education | 2020 |
| Shineshield Ltd | Professional & scientific | 2024 |
| Shining Star Classes Ltd | Education | 2024 |
| Shining Stars (London) Limited | Wholesale & retail | 2013 |
| Shining Stones Ltd | Wholesale & retail | 2025 |
| Shirlymat Limited | Health & social care | 2022 |
| Shirzad Locum Ltd | Health & social care | 2023 |
| Shirzad Supplies Ltd | Agriculture & fishing | 2022 |
| Shiv Shakti Hounslow Ltd | Wholesale & retail | 2022 |
| Shiv Smiles Limited | Health & social care | 2024 |
| Shiva SAI Holdings Limited | Financial services | 2025 |
| Shivam Consultants Ltd | Administrative & support | 2022 |
| Shivaneesha Ltd | Extraterritorial | 2020 |
| Shivani Enterprises UK Ltd | Wholesale & retail | 2025 |
| Shivani Supermarket Ltd | Wholesale & retail | 2025 |
| Shivkrupa Shakti Ltd | Hospitality | 2025 |
| Shivlakshmi Tech Ltd | Information & communication | 2022 |
| Shivoo Limited | Administrative & support | 2014 |
| SHJ Legal Ltd | Professional & scientific | 2018 |
| SHO Care Limited | Health & social care | 2014 |
| Shona Investments Ltd | Real estate | 2025 |
| Shona Ltd | Information & communication | 2019 |
| Shop & Save OFF Licence Ltd | Wholesale & retail | 2012 |
| Shop 23 London Limited | Wholesale & retail | 2018 |
| Shop and Ship Cargo Ltd | Transport & logistics | 2025 |
| Shop in ALL Ltd | Wholesale & retail | 2026 |
| SHOP44 Limited | Wholesale & retail | 2018 |
| Shopeefy Limited | Wholesale & retail | 2017 |
| Shopezone Ltd | Wholesale & retail | 2025 |
| Shopfronts Shutters Ltd | Construction | 2018 |
| Shopria Ltd | Wholesale & retail | 2025 |
| Shopskey Limited | Information & communication | 2024 |
| Shorsh Limited | Wholesale & retail | 2013 |
| Short Eats -UK Ltd | Hospitality | 2019 |
| Shrani Investments Ltd | Real estate | 2018 |
| Shree Mahaveer Ltd | Real estate | 2017 |
| Shree Pharmahealth Ltd | Wholesale & retail | 2026 |
| Shree Sairam Properties Ltd | Real estate | 2020 |
| Shreekrishna Solutions Limited | Information & communication | 2011 |
| Shreem Accoutants & Tax Advisors Ltd | Professional & scientific | 2025 |
| Shreem Builder Limited | Construction | 2025 |
| Shreewinconsulting Limited | Information & communication | 2015 |
| Shri Bajrang Properties Ltd | Real estate | 2025 |
| Shri Balaji Real Estate Limited | Real estate | 2020 |
| Shri Kailashgiri Digamber Jain Community Ltd | Other services | 2012 |
| Shri Venkateshwara Developers Ltd | Construction | 2025 |
| Shrigurunanakdevji Co Ltd | Real estate | 2025 |
| Shros Technologies Ltd | Information & communication | 2018 |
| SHS Global Motors & Retails Ltd | Wholesale & retail | 2026 |
| SHS Sales Store Ltd | Wholesale & retail | 2024 |
| Shub Properties Ltd | Real estate | 2018 |
| Shubh Deol Ltd | Transport & logistics | 2026 |
| Shubh Transport Ltd | Transport & logistics | 2024 |
| Shubhyant Consulting Ltd | Hospitality | 2026 |
| Shutters 'N' Blinds Ltd | Wholesale & retail | 2010 |
| Shyam Baba UK Ltd | Wholesale & retail | 2025 |
| Shybrows Ltd | Other services | 2019 |
| Shyne Surgical Ltd | Manufacturing | 2012 |
| SI Aesthetics Limited | Health & social care | 2021 |
| Siazaidi Concierge Ltd | Transport & logistics | 2022 |
| Sicario International Secuirty Ltd | Administrative & support | 2022 |
| SID Car Sales Limited | Wholesale & retail | 2016 |
| Sidak Construction Ltd | Construction | 2026 |
| Sidhu and Daughters Ltd | Education | 2019 |
| Sidhu Freight Services Ltd | Transport & logistics | 2021 |
| Sigma Corporation Ltd | Wholesale & retail | 2012 |
| Sigma Marketing Limited | Professional & scientific | 2025 |
| Signalgrange Limited | Real estate | 1985 |
| Signature London Assets Ltd | Real estate | 2018 |
| Signovate Advertising Ltd | Professional & scientific | 2023 |
| Signs ETC Ltd | Manufacturing | 2018 |
| Sigrid Bris Ltd | Professional & scientific | 2021 |
| Sikh Human Rights Group | Professional & scientific | 2021 |
| Sikh Wisdom Ltd | Education | 2021 |
| SIL Trans Ltd | Administrative & support | 2025 |
| Silcart Ltd | Wholesale & retail | 2026 |
| Silicon Technologies Ltd | Other services | 2010 |