| Satvik Steel Ltd | Wholesale & retail | 2018 |
| Satwik Consultancy Services Limited | Information & communication | 2010 |
| Satyam Infotech Limited | Information & communication | 2015 |
| Satyam Property Limited | Real estate | 2023 |
| Saul Cars Ltd | Transport & logistics | 2019 |
| Save 2 Electric Limited | Construction | 2025 |
| Savers Investments One Limited | Real estate | 2021 |
| Savi Construction Ltd | Construction | 2023 |
| Savile Consultants Ltd | Administrative & support | 2024 |
| Savisoft Limited | Information & communication | 2025 |
| Savorex Foods Ltd | Manufacturing | 2025 |
| Sawan LAB Ltd | Manufacturing | 2022 |
| Sayeetech Ltd | Information & communication | 2023 |
| SB Conveyancing Ltd | Professional & scientific | 2013 |
| SB Engineering Specialists Ltd | Professional & scientific | 2022 |
| SB Express Limited | Transport & logistics | 2018 |
| SB ROM Food Center Ltd | Manufacturing | 2016 |
| SB Tiling Services Ltd | Construction | 2023 |
| SBA Locum Ltd | Wholesale & retail | 2023 |
| Sbgd Ltd | Construction | 2026 |
| SBR Tools Limited | Wholesale & retail | 2024 |
| SBS Builts Ltd | Construction | 2026 |
| SC Building Contractors Ltd | Construction | 2024 |
| SC General Practice Ltd | Health & social care | 2024 |
| SCA Holdings Ltd | Real estate | 2015 |
| Scaffold & Design Limited | Construction | 2022 |
| Scarred Ltd | Manufacturing | 2015 |
| Scepter (U.K.) Limited | Information & communication | 1989 |
| Sceros Ltd | Wholesale & retail | 2019 |
| SCG Food Services Limited | Hospitality | 2025 |
| SCG Foods Limited | Hospitality | 2024 |
| Schenker Limited | Transport & logistics | 1943 |
| Schilthorn Watches Limited | Professional & scientific | 2011 |
| Schn Limited | Construction | 2026 |
| Scholar Financial Services Ltd | Financial services | 2022 |
| School Bells Ltd | Other services | 2012 |
| Schreiber Care UK Ltd | Health & social care | 2021 |
| Schyft Ltd | Transport & logistics | 2026 |
| Scinkare Ltd | Wholesale & retail | 2026 |
| Scissor & Comb Limited | Other services | 2025 |
| Scootersride Limited | Administrative & support | 2022 |
| Scooterwala Ltd | Administrative & support | 2025 |
| Scotch & Soda Ltd | Wholesale & retail | 2020 |
| Scrumptiously Delicious Ltd | Wholesale & retail | 2023 |
| Sculpt Beauty Cosmetics Limited | Other services | 2010 |
| Scv-Pondex Ltd | Transport & logistics | 2022 |
| SD Food & Wine Ltd | Wholesale & retail | 2024 |
| SD Grill Ltd | Hospitality | 2019 |
| SDA IT Solutions Limited | Information & communication | 2024 |
| Sdcc Ltd | Information & communication | 2026 |
| SDG Investment Partners Group Ltd | Real estate | 2023 |
| Sdhillon Logistics Ltd | Transport & logistics | 2025 |
| SDP Ltd | Manufacturing | 2025 |
| Sdxprim Ltd | Construction | 2023 |
| Sea Water Fresh Fish Ltd | Hospitality | 2025 |
| Seafood and EAT IT Limited | Manufacturing | 2004 |
| Sealtancy Maritime Solutions Ltd | Professional & scientific | 2025 |
| Searchglocal Ltd | Extraterritorial | 2020 |
| Seaworld Hounslow Ltd | Wholesale & retail | 2024 |
| Sebastian and Daughters Ltd | Professional & scientific | 2011 |
| Sebreaur Ltd | Wholesale & retail | 2025 |
| Second Life Cars Ltd | Wholesale & retail | 2024 |
| Secure Circuit Ltd | Professional & scientific | 2022 |
| Secure Connection Ltd | Other services | 2024 |
| Secure Response Limited | Wholesale & retail | 2018 |
| Security Plan Limited | Administrative & support | 2015 |
| SED Cafe Ltd | Hospitality | 2018 |
| Seda Developments Ltd | Construction | 2025 |
| Seda Estate 2 Limited | Real estate | 2019 |
| Seda Estate Limited | Real estate | 2019 |
| Seda Holdings Ltd | Financial services | 2019 |
| Seda Investments Ltd | Real estate | 2023 |
| Sediqi and Sediqi Limited | Professional & scientific | 2022 |
| Seehra Logistics Ltd | Transport & logistics | 2023 |
| Seema Khan Limited | Professional & scientific | 2020 |
| Seema Rani Transport Ltd | Transport & logistics | 2025 |
| Seen Investments Limited | Real estate | 2025 |
| Seer Property Services Limited | Real estate | 2020 |
| Seerattrading Limited | Other services | 2025 |
| Sefali's Yoga Ltd | Health & social care | 2015 |
| Segrus Delta Ltd | Information & communication | 2022 |
| Segue Investments Limited | Real estate | 2023 |
| Sehaj PVT Limited | Wholesale & retail | 2021 |
| Sehgal & Sons Limited | Wholesale & retail | 2013 |
| Sehgal and Grandsons Private Limited | Wholesale & retail | 2020 |
| Sehgal Real Estate Ltd | Real estate | 2026 |
| Seife Solutions Limited | Wholesale & retail | 2010 |
| Seil UK Ltd | Manufacturing | 2016 |
| Sekhon Dwellings Ltd | Construction | 2023 |
| Sekhon Residential Ltd | Real estate | 2025 |
| Sela Hand Car Wash Ltd | Other services | 2019 |
| Selective Ventures Ltd | Professional & scientific | 2014 |
| Selekt Cars Ltd | Wholesale & retail | 2024 |
| Selekt Fast Foods Limited | Hospitality | 2019 |
| Semanta Limited | Information & communication | 2018 |
| Semantic Computing Ltd | Information & communication | 2016 |
| Semipravak Electronics Limited | Administrative & support | 2023 |
| Senacare Ltd | Health & social care | 2012 |
| Seneca Aviation Ltd | Transport & logistics | 2011 |
| Senseaurae Ltd | Health & social care | 2025 |