| Brookside Engine Company Limited | Manufacturing | 2011 |
| Budds Bakery Ltd | Hospitality | 2021 |
| Build Master NW Ltd | Construction | 2020 |
| Built Wright Construction Ltd | Construction | 2015 |
| Bukharaa Chapel Ltd | Hospitality | 2025 |
| Bulls Head Chapel Ltd | Real estate | 2021 |
| Burford Brothers Ltd | Agriculture & fishing | 2025 |
| Burnside Properties (JRS) Ltd | Real estate | 2023 |
| Busy Bees Domestic Cleans Ltd | Administrative & support | 2025 |
| Butterworth Enterprises Limited | Professional & scientific | 1999 |
| Buxton Raceway Limited | Arts & recreation | 1997 |
| Buxworth Pre-School | Education | 2009 |
| C & L Theaker Ltd | Information & communication | 2016 |
| C B Property Solutions Limited | Construction | 2018 |
| C&C Catering Solutions Limited | Hospitality | 2022 |
| C.J. Patton Data Communications Ltd | Construction | 2003 |
| C.T. Construction Limited | Construction | 1993 |
| Cafe Chaps Ltd | Hospitality | 2024 |
| Calamata Eight Limited | Administrative & support | 2005 |
| Calamata Five Limited | Administrative & support | 2005 |
| Calamata Two Limited | Administrative & support | 2005 |
| Calcutt Business Consultancy Limited | Information & communication | 2003 |
| Caloy Limited | Extraterritorial | 1960 |
| Calton Saddlery Services Limited | Manufacturing | 2016 |
| Cambridge Risk Solutions Limited | Professional & scientific | 2005 |
| Campaign for Plain English Limited | Professional & scientific | 2000 |
| Campervans-En-Le-Frith Limited | Wholesale & retail | 2021 |
| Canmore Limited | Information & communication | 2017 |
| Car Audio Repair Specialists Ltd | Other services | 2016 |
| Carbonsix Creative Limited | Professional & scientific | 2012 |
| Caroline Warren Ltd | Hospitality | 2024 |
| Carolyn Wilkins Consulting Limited | Professional & scientific | 2021 |
| Carter & Carter Solicitors Ltd | Professional & scientific | 2006 |
| Carter and Sons Haulage Ltd | Transport & logistics | 2021 |
| CAS Building Services Partnership Limited | Construction | 2013 |
| Casswell CAD Services Limited | Professional & scientific | 2006 |
| Castex Products Limited | Manufacturing | 1982 |
| Castle & Sons Building Ltd | Construction | 2019 |
| Castle Construction (NW) Ltd | Construction | 2023 |
| Castle Edge Leisure Limited | Hospitality | 2022 |
| Catch Pro Angling Ltd | Wholesale & retail | 2025 |
| Cayenne People Development Limited | Professional & scientific | 2014 |
| CB Training (International) Ltd | Transport & logistics | 2016 |
| CD Grayson Holdings Limited | Financial services | 2023 |
| Cdacla Ltd | Financial services | 2020 |
| Celebrate Catering Ltd | Hospitality | 2020 |
| Celestial Bows Ltd | Manufacturing | 2025 |
| Centrade Ltd | Wholesale & retail | 2020 |
| Central Station Properties Ltd | Households | 2019 |
| Chalk Board Services Limited | Professional & scientific | 2006 |
| Chap in the Box Studios Ltd | Information & communication | 2019 |
| Chapel & District Riding Club | Arts & recreation | 2026 |
| Chapel Butchers Block Ltd | Wholesale & retail | 2025 |
| Chapel DIY Centre Limited | Wholesale & retail | 1992 |
| Chapel Garage (Chapel-En-Le-Frith) Ltd | Wholesale & retail | 2011 |
| Chapel Golf Club (Trading) Ltd | Arts & recreation | 2016 |
| Chapel PO Ltd | Transport & logistics | 2013 |
| Chapel&District Bespoke Care Ltd | Health & social care | 2019 |
| Chapel-En-Le-Frith Golf Club Limited | Arts & recreation | 1912 |
| Charbo Precision Limited | Manufacturing | 2014 |
| Charles River Laboratories England Limited | Professional & scientific | 2026 |
| Charley Enterprises Ltd | Other services | 2011 |
| Charnatash Ltd | Real estate | 2011 |
| Cheadle Tanning Studio Ltd | Other services | 2016 |
| Checkbar Ltd. | Administrative & support | 2017 |
| Cheeky Monkeys Day Nursery (Chapel) Limited | Education | 2003 |
| Chemquip Limited | Manufacturing | 1980 |
| Cheshire Bikers Ltd | Other services | 2023 |
| Cheshire Hearing Centres Limited | Wholesale & retail | 2015 |
| Cheshire Mobile Tyres Ltd | Extraterritorial | 2019 |
| Cheshire North Roofing Limited | Construction | 2017 |
| Chester Park Properties Limited | Real estate | 2007 |
| Chris Foster Brickwork Ltd | Construction | 2022 |
| Christinemaurice Limited | Real estate | 2024 |
| Christopher Saunders LLP | | 2012 |
| Church Street Living Ltd | Real estate | 2021 |
| Citrus Retail Ltd | Wholesale & retail | 2005 |
| City and Town Properties Ltd | Real estate | 2018 |
| CJB Aircraft Engineering Ltd | Manufacturing | 2026 |
| CJK Packaging Limited | Administrative & support | 2003 |
| Claire Bradshaw Associates Limited | Education | 2018 |
| Claire Gascoyne PR Ltd | Professional & scientific | 2014 |
| Clare and Andrew Murdoch Limited | Administrative & support | 2013 |
| Clare Halpin Clinical Expert Services Limited | Health & social care | 2019 |
| Clayton and Clayton Accountants LLP | | 2017 |
| Clayton CCA Ltd | Administrative & support | 2018 |
| Cleanlyco Limited | Administrative & support | 2026 |
| Clear Space House Clearance Company Ltd | Wholesale & retail | 2025 |
| Clearglaze DG Limited | Wholesale & retail | 2009 |
| Cleavr Limited | Professional & scientific | 2017 |
| Click Partnership Limited | Professional & scientific | 1998 |
| Clockwork Cafe Ltd | Hospitality | 2025 |
| Cloughfield & Co Ltd | Wholesale & retail | 2025 |
| Cmts Training Solutions Limited | Extraterritorial | 2012 |
| CMW Bookkeeping Services Ltd | Professional & scientific | 2026 |
| Coaldale Properties Limited | Real estate | 2005 |
| Coast to Coast Boot Company Limited | Wholesale & retail | 1996 |
| Codetta Limited | Professional & scientific | 2015 |
| Collamere Ltd | Wholesale & retail | 2011 |
| Colledge Vintage Engineering Ltd | Wholesale & retail | 2023 |