| Squeegee App Limited | Information & communication | 2019 |
| Squeeze ME Club Ltd | Hospitality | 2025 |
| SRD Utilities Ltd | Construction | 2018 |
| SRP Biomass Services Limited | Construction | 2023 |
| Srsm Property Ltd | Real estate | 2024 |
| SS Cheltenham Limited | Real estate | 2026 |
| SS Hereford Limited | Hospitality | 2024 |
| ST Albans Development Ltd | Real estate | 2017 |
| ST Albans Residential Limited | Real estate | 2019 |
| ST Eigons Spring Farm Limited | Hospitality | 2021 |
| ST James 29 Property Management Limited | Households | 2011 |
| ST James Court Management (Hereford) Limited | Households | 2008 |
| ST Joseph's Estate Company Limited | Households | 2008 |
| ST Joseph's Flats Management Company Limited | Households | 2008 |
| ST Martin's Developments (Hereford) Ltd | Construction | 2013 |
| ST Mary's Church of England Primary Academy, Dilwyn | Education | 2011 |
| ST Mary's View MC Ltd | Households | 2018 |
| ST Michael's Hospice (Incorporating the Freda Pearce Foundation) | Health & social care | 1982 |
| ST Michael`S Hospice Development Company Limited | Extraterritorial | 2009 |
| ST Mina Ltd | Education | 2020 |
| ST Nicholas Close Hereford Management Company Limited | Households | 2024 |
| ST Nicholas Gate Management Company Limited | Real estate | 2001 |
| ST Owen Studio Limited | Health & social care | 2009 |
| ST Paul's Church of England Primary School | Education | 2012 |
| ST Peter's Consultancy Limited | Financial services | 2026 |
| ST. Augustines Court Residential Limited | Households | 1996 |
| ST. Charles House Residents Company Limited | Households | 1987 |
| ST. Marys Burghill Manco Limited | Households | 1998 |
| ST. Nicholas Court Management (Hereford) Company Limited | Households | 1992 |
| ST14 Fole Management Limited | Households | 2024 |
| Stair Compare Limited | Manufacturing | 2022 |
| Stakertaker Ltd | Information & communication | 2023 |
| Stanton Wong Ltd | Hospitality | 2021 |
| Star Vision Global Limited | Professional & scientific | 2021 |
| Starcozza Limited | Real estate | 2024 |
| Station Auto Services Limited | Wholesale & retail | 1997 |
| Station Yard Services Limited | Wholesale & retail | 2010 |
| Staunton on WYE Nursing Home Ltd | Health & social care | 2015 |
| Stead Enterprises Ltd | Hospitality | 2016 |
| Steady ST8 Design Services Ltd | Professional & scientific | 2023 |
| Steam Events Limited | Arts & recreation | 1989 |
| Steel Eagle International Limited | Administrative & support | 2012 |
| Steelclad Solutions Limited | Construction | 2024 |
| Steels of Hereford Limited | Professional & scientific | 2008 |
| Steels Westgate Limited | Wholesale & retail | 1980 |
| Stella Agri Services Ltd | Agriculture & fishing | 2022 |
| Stepcor Ltd | Hospitality | 2018 |
| Steph-Rad Ltd | Health & social care | 2025 |
| Stephens Productions Limited | Professional & scientific | 2015 |
| Sterling Building Ltd | Construction | 2022 |
| Steve Body Industrial Services Ltd | Professional & scientific | 2022 |
| Steve C Collins Consultant Ltd | Professional & scientific | 2026 |
| Steve Jones Building Contractors Limited | Construction | 2013 |
| Steven Samuel Franklin Limited | Extraterritorial | 2025 |
| Stewart Gallery Ltd | Wholesale & retail | 2022 |
| Stirling & Green Limited | Real estate | 2024 |
| Stirling Court Management Company Hereford Limited | Households | 2015 |
| Stirling Risk Management Ltd | Administrative & support | 2026 |
| Stirnet Limited | Information & communication | 1989 |
| STJ Lewis & SON Limited | Agriculture & fishing | 2010 |
| STL Energy Limited | Administrative & support | 2010 |
| STL Energy Property Limited | Real estate | 2024 |
| STL Environmental Limited | Water & waste | 2024 |
| Stockholding Solutions Limited | Wholesale & retail | 2008 |
| Stocks Engineering Limited | Manufacturing | 2008 |
| Stok.Ly Limited | Administrative & support | 2015 |
| Stoke Edith Property Company Limited | Administrative & support | 2000 |
| Stoke Stores Limited | Wholesale & retail | 2025 |
| Stone & Coast Property Ltd | Real estate | 2017 |
| Stone Group Holding Ltd | Financial services | 2024 |
| Stone Promotions Limited | Professional & scientific | 2026 |
| Stoned & Stacked Ltd | Extraterritorial | 2025 |
| Stonehouse Holdings Limited | Administrative & support | 1992 |
| Stoney Orchard Developments Limited | Construction | 2022 |
| Stoney Orchard Residents Management Company Limited | Households | 2023 |
| Storm Hairdressing Ltd | Other services | 2003 |
| Stour Solutions Limited | Professional & scientific | 2004 |
| Stourton Developments Limited | Real estate | 2026 |
| Stovetech Limited | Wholesale & retail | 2010 |
| STP Logistics Limited | Wholesale & retail | 2011 |
| Strachan I P Limited | Professional & scientific | 2020 |
| Straight Line Design Ltd | Professional & scientific | 2019 |
| Stram Properties Ltd | Real estate | 2021 |
| Strand Investments Limited | Real estate | 1991 |
| Stratonex Global Ltd | Wholesale & retail | 2025 |
| Stretton Urology Limited | Health & social care | 2024 |
| Stride Active (Herefordshire) CIC | Education | 2020 |
| Stride Build Ltd | Construction | 2021 |
| Stride Care Ltd | Health & social care | 2021 |
| Stride Carpentry and Construction Ltd | Construction | 2026 |
| Stride Property Partners Ltd | Real estate | 2025 |
| Stride Roof Cleaning Ltd | Administrative & support | 2024 |
| Striderentals Ltd | Real estate | 2025 |
| Striking Building Services Limited | Real estate | 2003 |
| Strive Business Solutions Ltd | Professional & scientific | 2016 |
| Structural Coating Services Limited | Construction | 2009 |
| Studens Limited | Real estate | 2025 |
| Studio in Shadwell Limited | Arts & recreation | 2016 |
| Study Beyond English Ltd | Education | 2026 |
| Stump Cutters Limited | Agriculture & fishing | 2016 |