| Selene Couture (UK) Ltd | Wholesale & retail | 2022 |
| Selenite Holdings Limited | Real estate | 2020 |
| Self Build Construction Ltd | Construction | 2020 |
| Self Building Technology Ltd | Construction | 2020 |
| Self-Esteem Hub Ltd | Professional & scientific | 2025 |
| Selhi Properties Limited | Real estate | 2017 |
| Selina’S Petals Ltd | Wholesale & retail | 2020 |
| Sell in Pound Ltd | Wholesale & retail | 2026 |
| Sell Online Leeds Ltd | Administrative & support | 2024 |
| Sella Style Ltd | Professional & scientific | 2023 |
| Selliah BTL Limited | Real estate | 2018 |
| Selliah Investments Limited | Real estate | 2022 |
| Selly Hill Enterprise Limited | Administrative & support | 2016 |
| Selmath Construction Ltd | Construction | 2024 |
| Seltec Ltd | Wholesale & retail | 2012 |
| Selva Estates Ltd | Real estate | 2024 |
| Selva Homes Ltd | Real estate | 2024 |
| Selvad Limited | Other services | 2008 |
| Selvi Enterprises Limited | Real estate | 2016 |
| Selwood Properties Ltd | Real estate | 2019 |
| Selze Ltd | Wholesale & retail | 2024 |
| SEM Property Management Limited | Administrative & support | 2007 |
| Semantex Limited | Information & communication | 2015 |
| Semilattice Ltd | Information & communication | 2021 |
| Semper Vigilance Limited | Professional & scientific | 2012 |
| Semperf Ltd | Professional & scientific | 2021 |
| SEN Associates Limited | Financial services | 2013 |
| SEN Supply Limited | Administrative & support | 2024 |
| Senate House Estate Limited | Real estate | 2022 |
| SENGASARAH3 Limited | Health & social care | 2016 |
| Sense Wellbeing Ltd | Health & social care | 2026 |
| Senseforge Ltd | Information & communication | 2025 |
| Sensepark Properties Limited | Construction | 1990 |
| Sensible Supplies Limited | Extraterritorial | 2019 |
| Sensoriaa Club Ltd | Hospitality | 2026 |
| Sensoriam Ltd | Wholesale & retail | 2015 |
| Sentara Limited | Professional & scientific | 2014 |
| Sentinel AI Grade Ltd | Manufacturing | 2019 |
| Sentinelle Group Ltd | Transport & logistics | 2025 |
| Sentire Property Services Ltd | Real estate | 2022 |
| Seoul LAB Limited | Hospitality | 2024 |
| September Court Residents Company Limited | Households | 1986 |
| Sequana Lifesciences Ltd | Manufacturing | 2019 |
| Sequel Support Ltd | Health & social care | 2020 |
| Sequence Partners Limited | Real estate | 2017 |
| Sequoia Acquisitions Ltd | Real estate | 2024 |
| Sequoia Acres Ltd | Construction | 2016 |
| Sequoia Assets Ltd | Real estate | 2024 |
| Sequoia Living Developments Ltd | Real estate | 2018 |
| Seren Care Services Limited | Health & social care | 2026 |
| Serena Park Limited | Real estate | 2018 |
| Serendib Cricket Club & Crawley Cricket Academy Ltd | Arts & recreation | 2023 |
| Serendib Imports Ltd | Wholesale & retail | 2024 |
| Serene Aesthetics Ltd | Health & social care | 2020 |
| Serene Consulting Ltd | Professional & scientific | 2015 |
| Serene Creations Limited | Wholesale & retail | 2023 |
| Serene Medics Ltd | Health & social care | 2025 |
| Serene Visions Ltd | Arts & recreation | 2018 |
| Serenity Chauffeurs Ltd | Transport & logistics | 2024 |
| Serenity House Complex Care Ltd | Health & social care | 2026 |
| Serenity Trans Ltd | Transport & logistics | 2019 |
| Serenity-V Ltd | Wholesale & retail | 2016 |
| Sergio Construct Ltd | Construction | 2017 |
| Sergiu-Florin Munteanu Ltd | Hospitality | 2021 |
| Serious BOY Productions Limited | Professional & scientific | 2009 |
| Serious Time Pass Limited | Information & communication | 2024 |
| Seriously Scilly Ltd | Real estate | 2019 |
| Served Utility Limited | Professional & scientific | 2023 |
| Server Consultancy Ltd | Wholesale & retail | 2004 |
| Service Edge Ltd | Administrative & support | 2025 |
| Service Mapping Ltd | Construction | 2022 |
| Servipharm Limited | Wholesale & retail | 1989 |
| SES Solutions Ltd | Administrative & support | 2010 |
| Sesu Properties Ltd | Real estate | 2024 |
| Set-International Ltd | Hospitality | 2025 |
| SET73 Ltd | Professional & scientific | 2026 |
| Setdrive Limited | Real estate | 2004 |
| Setforce Ltd | Construction | 2024 |
| Seth the Pilot Ltd | Education | 2020 |
| Sethu Investments Ltd | Real estate | 2022 |
| Setra Solutions Ltd | Wholesale & retail | 2020 |
| Settld Home Ltd | Real estate | 2020 |
| Settld Home Stays Ltd | Wholesale & retail | 2020 |
| Settld Home TOO Ltd | Wholesale & retail | 2020 |
| Settle Homes Limited | Construction | 2010 |
| Seva Care (Respite and Residential Services) Limited | Health & social care | 2008 |
| Seva Education, Health & Care Ltd | Education | 2019 |
| Seva Holidays Limited | Hospitality | 2020 |
| Seva Patidar Limited | Wholesale & retail | 2003 |
| Seva Property Holdings Ltd | Real estate | 2021 |
| Seva Wellness Centre Ltd | Other services | 2024 |
| Sevaka Ltd | Hospitality | 2016 |
| Sevan Motors Limited | Wholesale & retail | 2004 |
| Seven & Co Trading Ltd | Hospitality | 2023 |
| Seven Communications GFE Limited | Professional & scientific | 2013 |
| Seven Decades Productions Ltd | Administrative & support | 2016 |
| Seven Hills Property Developers Limited | Real estate | 2020 |
| Seven Oceans Ltd | Other services | 2018 |
| Seven Sky Telecommunications Limited | Information & communication | 2018 |
| Seven Smart Buildings & Energy Ltd | Construction | 2024 |