| SD Property Ltd | Real estate | 2019 |
| SDA Innovations Ltd | Wholesale & retail | 2025 |
| Sdav Estates Limited | Real estate | 2023 |
| SDC Drylining Ltd | Construction | 2017 |
| SDC Group Construction Ltd | Construction | 2021 |
| SDK Technologies Limited | Information & communication | 2008 |
| Sdovj Limited | Health & social care | 2026 |
| SDR Trans Ltd | Transport & logistics | 2018 |
| Sdrn Investments Limited | Real estate | 2020 |
| Sdryco Limited | Construction | 2022 |
| SDS MIS Services Ltd | Information & communication | 2018 |
| Sds-Uk(Structural Design Solutions) Ltd | Construction | 2011 |
| SDV Connect Limited | Construction | 2022 |
| Sea Pebbles (UK) Limited | Real estate | 2003 |
| Sea Securities Limited | Construction | 1978 |
| Seabird 1 Ltd | Real estate | 2019 |
| Seabird 2 Ltd | Real estate | 2019 |
| Seabird 3 Limited | Real estate | 2019 |
| Seagrass Collection Ltd | Extraterritorial | 2021 |
| Seagull Chartering Limited | Transport & logistics | 2009 |
| Sealed & Ready Limited | Hospitality | 2020 |
| Seamless Education Ltd | Real estate | 2018 |
| Seamless Painting Ltd | Construction | 2025 |
| Sean Barrett Millinery Limited | Manufacturing | 2012 |
| Search Engine Rescue Limited | Information & communication | 2010 |
| Sears Accountants and Tax Advisors Ltd | Professional & scientific | 2023 |
| Sears Accountants Limited | Professional & scientific | 2016 |
| Seas Exports Ltd | Wholesale & retail | 2014 |
| Season Gone Ltd | Transport & logistics | 2026 |
| Seasonal Doors Consultants Ltd | Professional & scientific | 2023 |
| Seasoned Software Ltd | Information & communication | 2023 |
| Seasoning Development Ltd | Hospitality | 2010 |
| Seastone Realty Limited | Professional & scientific | 2023 |
| Seaton Square Ltd | Financial services | 2003 |
| Seats and Stay Limited | Wholesale & retail | 2023 |
| Seaview Beach Shop Limited | Wholesale & retail | 2021 |
| Seavine Limited | Real estate | 1995 |
| Seba General Builders Ltd | Construction | 2026 |
| Seba Holdings Limited | Real estate | 1989 |
| Sebastian Estates Ltd | Real estate | 2024 |
| Sebastian Solutions Ltd | Real estate | 2021 |
| Sebright Property Management Limited | Real estate | 2013 |
| SEC Contracting Ltd | Construction | 2020 |
| SEC Roofings Ltd | Construction | 2025 |
| Seceng.Io Ltd | Administrative & support | 2020 |
| Second Bite Again Ltd | Hospitality | 2025 |
| Second Minute Hour Watch Ltd | Wholesale & retail | 2026 |
| Secondary First | Professional & scientific | 2015 |
| Secret Doctor Ltd | Wholesale & retail | 2024 |
| Secret Hero Limited | Information & communication | 2006 |
| Secret of Indian Masala Ltd | Hospitality | 2019 |
| Secret Saviours Limited | Manufacturing | 2008 |
| Secret Savoury Ltd | Wholesale & retail | 2026 |
| Securaze UK Ltd | Information & communication | 2021 |
| Secure Boundaries Limited | Construction | 2025 |
| Secure Consultancy Limited | Professional & scientific | 2012 |
| Secure Sale Property Group Limited | Real estate | 2023 |
| Secure Threads Limited | Information & communication | 2024 |
| Secure Trade Limited | Wholesale & retail | 2008 |
| Secure Web & Mobile Software Systems Limited | Information & communication | 2016 |
| Securecloud Limited | Information & communication | 2026 |
| Secured Solutions 360 Ltd | Administrative & support | 2011 |
| Securesol Ltd | Information & communication | 2013 |
| Securesol Properties Ltd | Construction | 2024 |
| Securitism Ltd | Information & communication | 2009 |
| Security Funding Limited | Financial services | 2011 |
| Securus Safe Deposit Centres Ltd | Administrative & support | 2015 |
| Securus Securities Limited | Administrative & support | 2015 |
| Sedeq Tyres Ltd | Wholesale & retail | 2026 |
| SEE Asia Tours Ltd | Administrative & support | 2016 |
| SEE KIT Here Limited | Wholesale & retail | 2019 |
| SEE Properties Limited | Real estate | 2018 |
| SEE Trading Ltd | Wholesale & retail | 2025 |
| Seed Consultants Limited | Professional & scientific | 2022 |
| Seeking Justice Limited | Education | 2023 |
| Seem Constructions Ltd | Manufacturing | 2025 |
| Seemai Ltd | Hospitality | 2018 |
| Seen Consultancy Limited | Professional & scientific | 2018 |
| Seer Infotech Ltd | Information & communication | 2012 |
| SEF Connect Ltd | Construction | 2021 |
| Sega Investments Limited | Real estate | 2024 |
| Seghir Design Ltd | Construction | 2024 |
| Sehgal Project Services Ltd | Professional & scientific | 2026 |
| Sehra LLP | | 2010 |
| SEI Sorelle Swimwear Ltd | Wholesale & retail | 2019 |
| Seia Global Ltd | Professional & scientific | 2024 |
| Seico Chauffeur Services Limited | Transport & logistics | 2006 |
| Seis Support Services Limited | Administrative & support | 2013 |
| Sejal Anujah Shah Couture Limited | Manufacturing | 2024 |
| Sejpal Holdings Ltd | Wholesale & retail | 2020 |
| Sekem Solutions Limited | Health & social care | 2013 |
| Sekkei Consultants Ltd | Administrative & support | 2018 |
| Seladore Studios Ltd | Wholesale & retail | 2025 |
| Selecket Clean Services -Carpet & Upholstery Steam Cleaning Specialist Ltd | Administrative & support | 2024 |
| Select Hospitality Limited | Information & communication | 2011 |
| Selective Assets Limited | Real estate | 2019 |
| Selective Properties Ltd | Construction | 2009 |
| Selectline Technology Limited | Information & communication | 1998 |
| Selectpay (Sidcup) Limited | Real estate | 2005 |
| Selekt Chicken Harrow Ltd | Hospitality | 2026 |