| Seven Spoons Food UK Limited | Wholesale & retail | 2024 |
| Sevenseas International Limited | Water & waste | 2009 |
| Seventeeneight Ltd | Wholesale & retail | 2024 |
| Seventh String Limited | Administrative & support | 2003 |
| Seventy & Mochi Limited | Wholesale & retail | 2020 |
| Sevenwalls Ltd | Wholesale & retail | 2020 |
| SEW Dope Creative CIC | Manufacturing | 2025 |
| Seyedmed Ltd | Health & social care | 2026 |
| Seylark Cars Ltd | Wholesale & retail | 2024 |
| Seymour Project Management Limited | Professional & scientific | 2014 |
| Seymour Property Management Ltd | Real estate | 2018 |
| Seyon Medical Services Limited | Health & social care | 2014 |
| Sezer Cafe Limited | Hospitality | 2013 |
| SF Body Imaging Limited | Health & social care | 2021 |
| SF Flow State Limited | Administrative & support | 2024 |
| SF Innovators Ltd | Wholesale & retail | 2026 |
| SF Youth Centre Ltd | Real estate | 2026 |
| SFA Safe Hand Limited | Health & social care | 2019 |
| SFD Lettings Ltd | Real estate | 2025 |
| SFH Goldsboro Road Ltd | Real estate | 2022 |
| Sfin Consulting Ltd | Administrative & support | 2017 |
| SFR 14 Ltd | Hospitality | 2026 |
| SFS Construct Ltd | Construction | 2015 |
| SFS Enterprises Ltd | Construction | 2022 |
| SG Aero Ltd | Professional & scientific | 2024 |
| SG Chicken Valley LLP | | 2017 |
| SG Decorating Services Limited | Construction | 2019 |
| SG Real Estate Ltd | Real estate | 2018 |
| SGK Stanmore Limited | Health & social care | 2013 |
| SGM Accounting Limited | Professional & scientific | 2014 |
| Sgnal Ltd | Information & communication | 2022 |
| SGR Investment Property Limited | Real estate | 2020 |
| SGR Property Management Limited | Real estate | 2017 |
| SGV & Sons Ltd | Wholesale & retail | 2011 |
| Sgvm Ltd | Health & social care | 2025 |
| SH Bodycoach Limited | Other services | 2020 |
| SH Food Trading Limited | Hospitality | 2024 |
| SH Premium Installations Ltd | Construction | 2026 |
| SH Projects Ltd | Real estate | 2024 |
| SH Real Property Ltd | Real estate | 2024 |
| SH Style Ltd | Other services | 2026 |
| SH09VAN Enterprises Ltd | Real estate | 2026 |
| Shaadi in Style Ltd | Other services | 2010 |
| Shaan Property Investments Ltd | Real estate | 2021 |
| Shaanu Ltd | Hospitality | 2023 |
| Shaban GAS & Plumbing Limited | Manufacturing | 2015 |
| Shabby BUT Chic Limited | Wholesale & retail | 2018 |
| Shade 7 Limited | Information & communication | 2012 |
| Shade 7 Publishing Limited | Information & communication | 2013 |
| Shade 7 Publishing Services Ltd | Information & communication | 2021 |
| Shade Beauty Limited | Wholesale & retail | 2020 |
| Shade Group Management Limited | Real estate | 2024 |
| Shade Lettings Limited | Real estate | 2018 |
| Shade Properties Ltd | Real estate | 2016 |
| Shadow Gamma Ltd | Financial services | 2022 |
| Shadowfall Limited | Arts & recreation | 2022 |
| Shadyburn Ltd | Financial services | 2000 |
| Shafeec Ltd | Transport & logistics | 2017 |
| Shaftesbury Pharmacy Limited | Wholesale & retail | 2005 |
| Shaftesbury Property Partnership Ltd | Real estate | 2021 |
| Shah & Co Estates Ltd | Real estate | 2020 |
| Shah Analytics Ltd | Professional & scientific | 2020 |
| Shah GEE Textile UK Ltd | Wholesale & retail | 2024 |
| Shah Innovations Ltd | Professional & scientific | 2024 |
| Shah Investment Group Limited | Real estate | 2018 |
| Shah Motors Ltd | Wholesale & retail | 2018 |
| Shah Ventures Limited | Financial services | 2018 |
| Shah'Z Limited | Wholesale & retail | 2023 |
| Shaheen Butt Limited | Professional & scientific | 2017 |
| Shaheen Cosmetics UK Ltd | Wholesale & retail | 2024 |
| Shaheen's Style Limited | Other services | 2024 |
| Shahid Brothers UK Ltd | Wholesale & retail | 2025 |
| Shahid Wahab Coaching Limited | Arts & recreation | 2021 |
| Shahkart Ltd | Wholesale & retail | 2025 |
| Shahs Wealdstone Ltd | Hospitality | 2024 |
| Shailen Patel Smiles Limited | Health & social care | 2025 |
| Shaimad Property Ltd | Hospitality | 2016 |
| Shakahari Ltd | Wholesale & retail | 2024 |
| Shakari Ltd | Real estate | 2020 |
| Shake & Rush Limited | Real estate | 2018 |
| Shake and Rush Consulting Limited | Professional & scientific | 2024 |
| Shakeii Shakeii Asset Management Limited | Real estate | 2022 |
| Shakeii Shakeii Bracknell Ltd | Hospitality | 2021 |
| Shakeii Shakeii Ltd | Hospitality | 2023 |
| Shakeii Shakeii Wembley Ltd | Wholesale & retail | 2022 |
| Shakespeare Industrial Estate (Watford) Limited | Households | 2000 |
| Shakib Industries Ltd | Wholesale & retail | 2022 |
| Shakin Properties Ltd | Real estate | 2025 |
| Shakthy Property Ltd | Real estate | 2006 |
| Shakti Growth Ltd | Wholesale & retail | 2025 |
| Shalina Healthcare (UK) Limited | Administrative & support | 2024 |
| Shaliz Ventures Ltd | Administrative & support | 2023 |
| Sham Building Limited | Construction | 2021 |
| Shamih Consultancy Limited | Financial services | 2007 |
| Shamih Properties Limited | Real estate | 2016 |
| Shamila Properties Ltd | Real estate | 2005 |
| Shan Consultancy & Management Ltd | Professional & scientific | 2011 |
| Shandur Capital Limited | Professional & scientific | 2024 |
| Shandy Investment Ltd | Real estate | 2025 |
| Shane Auto Parts Limited | Wholesale & retail | 1999 |