| Standard Skate Republic Ltd | Extraterritorial | 2012 |
| Standen View (Lancaster) Management Company Limited | Households | 2005 |
| Standeven Estates Ltd | Real estate | 2013 |
| Stanford Portman Limited | Extraterritorial | 2026 |
| Stanley Peel Properties Limited | Real estate | 2026 |
| Stanley's Builders Holding Ltd | Construction | 2022 |
| Stanley's Builders Limited | Construction | 2003 |
| Stanton Hope CRE Limited | Administrative & support | 2016 |
| Stanton Pearce Associates Limited | Professional & scientific | 2017 |
| Star Business Growth Solutions Limited | Financial services | 2018 |
| Star Pizza Harrogate Ltd | Hospitality | 2025 |
| Starbeck Accommodation Ltd | Hospitality | 2026 |
| Starbeck Micro Hotel Ltd | Hospitality | 2025 |
| Starbeck Solutions Ltd | Information & communication | 2009 |
| Starbeck Star Ltd | Wholesale & retail | 2025 |
| Starbeck TR Ltd | Hospitality | 2025 |
| Stardust Productions Limited | Information & communication | 2013 |
| Starlit Innovations Ltd | Information & communication | 2025 |
| Stars UK Holdings Ltd | Manufacturing | 2019 |
| Stars UK R&D Ltd | Manufacturing | 2023 |
| Start Neuro Ltd | Manufacturing | 2026 |
| Station Road Crakehall Management Company Ltd | Households | 2026 |
| Staveley Holdings Limited | Financial services | 2024 |
| Staveley Sales Limited | Wholesale & retail | 2025 |
| Stay FLY Ltd | Information & communication | 2011 |
| Stay Green Limited | Extraterritorial | 2011 |
| STB Education Advisory Ltd | Education | 2026 |
| Steadman Brierley Securities LLP | | 2015 |
| Steadmont Ltd | Real estate | 2019 |
| Steca NO 6 Ltd | Other services | 2017 |
| Steel FM Ltd | Extraterritorial | 2015 |
| Steepbay Developments Limited | Households | 1987 |
| Stefan Schroder Consulting Ltd | Professional & scientific | 2020 |
| Stefano's Pizza Restaurant (UK) Ltd | Hospitality | 2024 |
| Steinel Fire & Security Ltd | Administrative & support | 2025 |
| Stellar Alliance Limited | Professional & scientific | 2023 |
| Stellar Capital Partners Limited | Extraterritorial | 2019 |
| Stellar FM Limited | Extraterritorial | 2015 |
| Stellar Systems Limitless Ltd | Transport & logistics | 2026 |
| Stem Consultants Limited | Professional & scientific | 2025 |
| Stenmark Limited | Extraterritorial | 2025 |
| Stenson Wealth Management Limited | Financial services | 2026 |
| STEPHAN1E Ltd | Extraterritorial | 2020 |
| Stephanie in Yorkshire Limited | Wholesale & retail | 2025 |
| Stephen Kennedy Consultancy Ltd | Professional & scientific | 2012 |
| Stephen King Auto Services Ltd | Wholesale & retail | 2012 |
| Stephen Murray Decorators Limited | Construction | 2003 |
| Stephen Neall Contracts Limited | Construction | 2000 |
| Stephen Neall Holdings Ltd | Construction | 2025 |
| Stephen Neall Interior Furnishers Limited | Construction | 2012 |
| Stephen Wood Architectural Services Limited | Professional & scientific | 2009 |
| Stephenson Control Systems Limited | Manufacturing | 1978 |
| Stephenson Findlay Limited | Professional & scientific | 2019 |
| Stephenson Wealth Limited | Financial services | 2014 |
| Stephensons Memorial Works LLP | | 2011 |
| Stepping Homes Limited | Real estate | 2011 |
| Stepwise Orthopaedic Surgery Ltd | Health & social care | 2025 |
| Sterling Rock Limited | Financial services | 2009 |
| Steve Ogden Engineering LLP | | 2010 |
| Steve Wells Associates Limited | Professional & scientific | 2002 |
| Stewell Ltd | Real estate | 2017 |
| Stiltskin Global Ltd | Wholesale & retail | 2021 |
| Stock-Turn (Leeds) Limited | Wholesale & retail | 2001 |
| Stockdale Group Limited | Extraterritorial | 2026 |
| Stocklot World Limited | Wholesale & retail | 2011 |
| Stocks and Shares Ltd | Wholesale & retail | 2024 |
| Stocks Family Office Limited | Real estate | 2023 |
| Stod FM Limited | Professional & scientific | 2021 |
| Stokes Consulting Limited | Professional & scientific | 2011 |
| Stone Bear Ltd | Information & communication | 2018 |
| Stone Heritage Group Ltd | Real estate | 2026 |
| Stone Meadow PM Ltd | Real estate | 2022 |
| Stone Rings Close Limited | Real estate | 2008 |
| Stonebeck Cheese Ltd | Extraterritorial | 2018 |
| Stonebridge Construction (Yorkshire) Limited | | 2006 |
| Stonebridge Mills Ltd | Construction | 2016 |
| Stonecross Care Home (Kendal) Ltd | Health & social care | 2014 |
| Stoneleigh Management (Harrogate) Limited | Households | 2001 |
| Stonestag Property Ltd | Hospitality | 2023 |
| Stoneyard Productions Ltd | Administrative & support | 2017 |
| Stopper Specialists Limited | Extraterritorial | 1999 |
| Storks Family Fisheries Ltd | Hospitality | 2025 |
| Storm Intelligent Communications Limited | Information & communication | 2010 |
| Storyteller Marketing Limited | Administrative & support | 2016 |
| STR1KE Ltd | Extraterritorial | 2020 |
| Straightforward Yorkshire Limited | Professional & scientific | 2020 |
| Strand Projects Limited | Other services | 2007 |
| Strategic and Performance Marketing Limited | Professional & scientific | 2021 |
| Strategy Enabled Group Ltd | Professional & scientific | 2026 |
| Strategy Enabled Ltd | Professional & scientific | 2019 |
| Stray Court (Harrogate) Limited | Administrative & support | 1988 |
| Stray Design Limited | Administrative & support | 2018 |
| Stray Digital Ltd | Information & communication | 2013 |
| Stray Garth Management Company Limited | Households | 1999 |
| Stray Golf Co. Ltd | Wholesale & retail | 2026 |
| Stray Group Ltd | Professional & scientific | 2023 |
| Stray Lodge Management Limited | Households | 1993 |
| Stray Media Ltd | Information & communication | 2015 |
| Stray View Management Limited | Real estate | 1986 |
| Strayside Cleaning Limited | Administrative & support | 2026 |