| Strayside Court (Harrogate) Services Limited | Households | 1960 |
| Strayside Mews Management Company Limited | Households | 1986 |
| Strayview Investments Limited | Real estate | 2021 |
| Streamcast(London) Limited | Administrative & support | 2025 |
| Streamline Flight Training Ltd | Education | 2021 |
| Streamscript Ltd | Information & communication | 2019 |
| Streamwise Limited | Professional & scientific | 1978 |
| Strebor Investments Limited | Administrative & support | 2020 |
| Street Meat Records Ltd | Wholesale & retail | 2020 |
| Striatum Limited | Professional & scientific | 2026 |
| Strikey's Computers Ltd | Information & communication | 2015 |
| Stringer Mallard Asset Finance Ltd | Financial services | 2026 |
| Stringer Mallard Audit Ltd | Professional & scientific | 2025 |
| Stringer Mallard Business Services Ltd | Professional & scientific | 2003 |
| Stringer Mallard Consulting Limited | Professional & scientific | 2010 |
| Stringer Mallard Ltd | Extraterritorial | 2025 |
| Stringer Mallard Nominees Ltd | Professional & scientific | 2012 |
| Stripe Leisure Consulting Ltd | Real estate | 2026 |
| Stripe Property Investments Limited | Construction | 2023 |
| Strive for Education Ltd | Education | 2019 |
| Strive Group Brands Ltd | Wholesale & retail | 2025 |
| Strive Group Events Ltd | Administrative & support | 2018 |
| Strive Group Holdings Ltd | Financial services | 2023 |
| Strive Group Limited | Administrative & support | 2001 |
| Strive Tennis Ltd | Arts & recreation | 2009 |
| Strower Ltd | Transport & logistics | 2025 |
| Structsure Limited | Professional & scientific | 2005 |
| Struggle Events Limited | Arts & recreation | 2016 |
| Stuart Parker Consultancy Limited | Professional & scientific | 2021 |
| Studenteer CIC | Administrative & support | 2020 |
| Students Rugby Football Union | Arts & recreation | 2001 |
| Studies Abroad Ltd | Wholesale & retail | 2024 |
| Studio 1 (Design and Production Services) Limited | Professional & scientific | 2003 |
| Studio by Elisa Interiors Limited | Wholesale & retail | 2026 |
| Studio Lagom Ltd | Professional & scientific | 2024 |
| Studio Nest Ltd | Construction | 2010 |
| Studio Pens Ltd | Wholesale & retail | 2005 |
| Studiverse Ltd | Information & communication | 2025 |
| Studleigh Advisory Services Ltd | Professional & scientific | 2025 |
| Studley Construction Ltd. | Wholesale & retail | 2004 |
| Studley Hotel Limited | Construction | 1970 |
| Stump Cross Limited | Arts & recreation | 2003 |
| Stumpp Limited | Information & communication | 2025 |
| Stumps Garage Limited | Wholesale & retail | 2009 |
| Stup Marketing Ltd | Professional & scientific | 2018 |
| Style Boutique (Yorkshire) Limited | Other services | 2021 |
| Style Official Ltd | Wholesale & retail | 2024 |
| Stylesmith Interiors Ltd | Professional & scientific | 2019 |
| Stylevents Ltd | Administrative & support | 2009 |
| Subservient Limited | Extraterritorial | 2012 |
| Suckerpunch Limited | Extraterritorial | 2011 |
| Suddaby Holdings Limited | Financial services | 2016 |
| Suffrago Limited | Information & communication | 2024 |
| Sugar & Lime Limited | Wholesale & retail | 2005 |
| Sugar & Lime Trustees Limited | Administrative & support | 2024 |
| Sukm Nominee Ltd | Real estate | 2024 |
| Sullivan & Sons Properties Ltd | Real estate | 2024 |
| Sultan Express Cafe Ltd | Hospitality | 2025 |
| SUM Expo Ltd | Transport & logistics | 2021 |
| Sumba Limited | Information & communication | 2012 |
| Summerstyle Limited | Other services | 2003 |
| Sumo Financial Services Ltd | Professional & scientific | 2014 |
| Sumptus (Bidco) Limited | Administrative & support | 2026 |
| Sumptus (Midco 1) Limited | Administrative & support | 2026 |
| Sumptus (Midco 2) Limited | Administrative & support | 2026 |
| Sun SET Apartments (Santorini) Ltd | Construction | 2016 |
| Sunday School Ventures Ltd | Other services | 2025 |
| Sunnyside Propco Limited | Real estate | 2022 |
| Sunrise Retail Limited | Hospitality | 2011 |
| Sunrise Takeaway Harrogate Limited | Hospitality | 2019 |
| Sunrise Urban Regeneration Limited | Construction | 2023 |
| Sunset Retail Limited | Hospitality | 2012 |
| Sunvale Trading Limited | Extraterritorial | 2016 |
| Sunyx Ltd | Health & social care | 2024 |
| Supaplants Limited | Professional & scientific | 1989 |
| Super De-Luxe Ltd | Extraterritorial | 2012 |
| SUPER1OR Limited | Wholesale & retail | 2021 |
| Suphouse Limited | Wholesale & retail | 2020 |
| Supreme Search Specialists HG Ltd | Administrative & support | 2022 |
| Supreme Search Specialists Ltd | Administrative & support | 2019 |
| Surepath Homes Ltd | Health & social care | 2024 |
| Surepath Properties Limited | Health & social care | 2024 |
| Suresmiths Limited | Professional & scientific | 2025 |
| Surety Health Limited | Construction | 2008 |
| Surfcontrol Limited | Professional & scientific | 1981 |
| Surge Accountants Ltd | Wholesale & retail | 2021 |
| Survey Connection Scotland Limited | Extraterritorial | 1991 |
| Susan Limited | Extraterritorial | 2012 |
| Sutcliffe Wealth Management Limited | Professional & scientific | 2023 |
| Suttill House Stays Limited | Hospitality | 2021 |
| Suzanne Clarke Life and Business Coach Limited | Other services | 2021 |
| Suzetta Limited | Professional & scientific | 2016 |
| Suzie Limited | Extraterritorial | 2020 |
| SVH Inc. CIC | Administrative & support | 2021 |
| SW48BHZB Limited | Households | 2016 |
| Swains Property (NE) Limited | Real estate | 2019 |
| Swallow Beck Investments Limited | Financial services | 2019 |
| Swamper Limited | Extraterritorial | 2021 |
| Swan Lifestyle Ltd | Hospitality | 2019 |
| Swanwick Morris LLP | | 2020 |