| DJ Broome Electrical Ltd | Construction | 2020 |
| DJ FOX MED Ltd | Health & social care | 2025 |
| DJ Houghton Holdings Limited | Financial services | 2020 |
| DJ Pharma Limited | Administrative & support | 2023 |
| DJG Environmental Ltd | Professional & scientific | 2017 |
| DJT Tarmac & Utility Services Ltd | Construction | 2022 |
| DJW Cars Limited | Wholesale & retail | 2026 |
| DKA Recruitment Ltd | Administrative & support | 2021 |
| DL Autos (UK) Ltd | Wholesale & retail | 2014 |
| DLH Landscapes Ltd | Administrative & support | 2024 |
| Dlml Services Limited | Wholesale & retail | 2017 |
| DLT Property Management Ltd | Real estate | 2023 |
| Dm&Bm Ltd | Real estate | 2021 |
| DMA (SW) Ltd | Professional & scientific | 2017 |
| DMC Property Limited | Real estate | 2016 |
| DMF Music Limited | Arts & recreation | 2008 |
| Dmgi Land & Property Europe Ltd | Professional & scientific | 1974 |
| DMI Property Services Limited | Real estate | 2020 |
| DMS Interiors South West Ltd | Construction | 2008 |
| DN Digital Limited | Information & communication | 2006 |
| DN Utilities Southwest Limited | Construction | 2026 |
| DNA Carpentry and Construction Ltd | Manufacturing | 2024 |
| DO Something Great Limited | Professional & scientific | 2023 |
| DO the Hard Things Ltd | Construction | 2023 |
| DOC Mayo Holdings Limited | Information & communication | 2024 |
| Docmayo Limited | Information & communication | 2023 |
| Docmilk Medical Services Limited | Health & social care | 2024 |
| Doctor O Ltd | Health & social care | 2026 |
| Documental Productions C.I.C. | Arts & recreation | 2021 |
| Dodd Aviation Limited | Professional & scientific | 2023 |
| Dodge Properties Ltd | Real estate | 2026 |
| Dogs Matter Ltd | Arts & recreation | 2015 |
| Dogware Ltd | Manufacturing | 2024 |
| Dolly's Film Club CIC | Arts & recreation | 2024 |
| Dolor OM Property Ltd | Real estate | 2015 |
| Dolor OM UK Ltd | Administrative & support | 2020 |
| Dolphin Mobility Solutions (South-West) Limited | Other services | 2016 |
| Dolphin Property Services Ltd | Real estate | 2019 |
| Dolphin Stairlifts (South West ) Ltd | Other services | 2013 |
| Dome Properties Ltd | Real estate | 2016 |
| DON Caffe & Lounge Ltd | Hospitality | 2024 |
| DON Hocken Limited | Real estate | 1933 |
| DON Stucco Ltd | Construction | 2026 |
| DON Team Delivery Ltd | Transport & logistics | 2025 |
| DON Valley Pharma (UK) Ltd | Professional & scientific | 2021 |
| Donahey's Events Limited | Administrative & support | 2003 |
| Donatis Giving Limited | Information & communication | 2014 |
| DONCO8 Unlimited | Professional & scientific | 2015 |
| Doneraile Residential Care Home Ltd | Health & social care | 2014 |
| Donerailercg Ltd | Health & social care | 2019 |
| Dongbang Acuprime Ltd | Wholesale & retail | 2001 |
| Donovan Properties Limited | Real estate | 1958 |
| Donovan Waite Consulting Ltd | Professional & scientific | 2020 |
| Dontsendmeacard.Com Ltd | Other services | 2013 |
| Don’T BE Alarmed! Limited | Arts & recreation | 2022 |
| Dood and Frink Ltd | Hospitality | 2021 |
| Doodlearth Ltd | Information & communication | 2021 |
| Doodlebug Botanical Ltd | Professional & scientific | 2026 |
| Doolin Group Ltd | Manufacturing | 2016 |
| Dormans Estate Agents Limited | Real estate | 2002 |
| Dormor Family Investment Company Ltd | Professional & scientific | 2020 |
| Dornaz Ghasemi Ltd | Professional & scientific | 2016 |
| Dorothy's Angels Ltd | Health & social care | 2024 |
| Dorrell Ltd | Professional & scientific | 2013 |
| Dorset Conservation Contractors Ltd | Agriculture & fishing | 2023 |
| Dorset Crane Hire Limited | Extraterritorial | 2021 |
| Dotage Investments Limited | Real estate | 2016 |
| Dottystripes Limited | Manufacturing | 2013 |
| Double AI Limited | Information & communication | 2025 |
| Double Elephant CIC | Arts & recreation | 2002 |
| Double Handed Offshore Ltd | Arts & recreation | 2020 |
| Double Luck Ltd | Hospitality | 2019 |
| Double Quick Windows Limited | Wholesale & retail | 2001 |
| Douglas Green Consulting Limited | Professional & scientific | 2009 |
| Douglas Seaton (Trading) Limited | Wholesale & retail | 1955 |
| Douglas Seaton Limited | Professional & scientific | 1929 |
| Dove Carpenters Limited | Construction | 2015 |
| Doves Car Care Ltd | Wholesale & retail | 2026 |
| Doves Moor Energy Park Limited | Energy | 2025 |
| Dowell Family Limited | Real estate | 2021 |
| Down House Limited | Health & social care | 2002 |
| Downbeach Ltd | Real estate | 2019 |
| DP Civils & Geotechnical Limited | Construction | 2023 |
| DP Incorporated Limited | Financial services | 2023 |
| DP Residential Lettings Ltd | Real estate | 2025 |
| DP Roofing Services Ltd | Construction | 2018 |
| DP Taylor Plumbing & Heating Ltd | Construction | 2024 |
| Dpas North Ltd | Professional & scientific | 2019 |
| Dpas Software Ltd | Information & communication | 2022 |
| Dpas Training Ltd | Professional & scientific | 2018 |
| DPD Transport Ltd | Transport & logistics | 2019 |
| DPF Restore Ltd | Wholesale & retail | 2023 |
| DPR Instrumentation Limited | Professional & scientific | 2009 |
| DPS Exeter Ltd | Construction | 2024 |
| DPS Residential Ltd | Real estate | 2016 |
| DR Bradley FME Services Limited | Health & social care | 2014 |
| DR Energy Futures Ltd | Professional & scientific | 2025 |
| DR G Psychiatry Limited | Health & social care | 2026 |
| DR J R Kennedy Sports Medicine Limited | Health & social care | 2024 |
| DR Logic Ltd | Information & communication | 2003 |