| Devon Underfloor Heating Ltd. | Construction | 2016 |
| Devon Valley Groundworks Limited | Construction | 2025 |
| Devon View Properties Ltd | Financial services | 2025 |
| Devon Waste Management Limited | Water & waste | 2014 |
| Devon Wildlife Support Community Interest Company | Professional & scientific | 2020 |
| Devon Wood Floors Ltd | Construction | 2010 |
| Devon Woodlands Limited | Agriculture & fishing | 2019 |
| Devon-Hemp Limited | Wholesale & retail | 2019 |
| Devonair Ltd | Information & communication | 2006 |
| Devoncare Ltd | Administrative & support | 2017 |
| Devonex Limited | Professional & scientific | 2003 |
| Devonia Estates Limited | Real estate | 1993 |
| Devonian Villa Management Company Limited | Households | 2004 |
| Devonshire Stone Limited | Manufacturing | 2012 |
| Devonshire Wessex Assets Limited | Other services | 2023 |
| Devonshire Wessex Management Limited | Financial services | 2021 |
| Devonshire Wessex Philanthropic Ltd | Education | 2021 |
| Devontech Limited | Manufacturing | 1985 |
| Devset Services Ltd | Administrative & support | 2010 |
| Dewality Consultants Limited | Mining & quarrying | 2012 |
| Dewby Pubs Limited | Hospitality | 2020 |
| Dexcode Limited | Administrative & support | 2023 |
| DF Engineering Solutions Ltd | Professional & scientific | 2026 |
| DFA Partnership Limited | Construction | 2013 |
| DFW Financial Ltd | Professional & scientific | 2021 |
| DFW Logistics Limited | Wholesale & retail | 2021 |
| DFW Warehousing Limited | Transport & logistics | 2026 |
| DGJ Plant Services Ltd | Manufacturing | 2021 |
| DGS Properties Limited | Real estate | 2024 |
| Dgwholesales Ltd | Other services | 2024 |
| DH Property and Letting Services Ltd | Real estate | 2025 |
| Dhand Properties Limited | Real estate | 2017 |
| Dhayal Properties Limited | Real estate | 2024 |
| Dhqs Ltd | Professional & scientific | 2012 |
| Dialectic Research Ltd | Professional & scientific | 2023 |
| Dialogue Exchange Global Limited | Information & communication | 2017 |
| Diamond Bookkeeping Solutions Limited | Professional & scientific | 2025 |
| Diamond Bristol Parking Limited | Transport & logistics | 2025 |
| Diamond CUT (SW) Ltd | Manufacturing | 2020 |
| Diamond CUT Detailing (Devon) Ltd | Manufacturing | 2024 |
| Diamond CUT Detailing (SW) Ltd | Manufacturing | 2020 |
| Diamond CUT Detailing Ltd | Manufacturing | 2019 |
| Diamond Parking Limited | Transport & logistics | 2017 |
| Diamond Stone Homes Ltd | Real estate | 2019 |
| Diamond Wolf Designs Ltd | Extraterritorial | 2020 |
| Diane Wills Therapist, Consultant & Coach Ltd. | Health & social care | 2014 |
| Diceabed International Limited | | 1982 |
| Dickens Showrooms Ltd | Wholesale & retail | 2012 |
| Dicky's Limited | Hospitality | 2021 |
| Didworthy Park Management Company Limited | Households | 2007 |
| DIG and Dump Limited | Administrative & support | 2025 |
| Digby Management and Consultancy Ltd | Construction | 2025 |
| Digginwell Holdings Limited | Financial services | 1997 |
| Digilab Solutions Ltd | Information & communication | 2021 |
| Digital Arrow Ltd | Information & communication | 2021 |
| Digital Bloom Marketing Limited | Information & communication | 2017 |
| Digital Health Training Ltd | Education | 2025 |
| Digital Jigsaw Ltd | Wholesale & retail | 2021 |
| Digital Resources Limited | Water & waste | 2019 |
| Digital Smart Home Solution UK Ltd | Wholesale & retail | 2023 |
| Digitherapix (2025) Limited | Information & communication | 2025 |
| Digitherapix Ltd | Information & communication | 2026 |
| Digivio Ltd | Information & communication | 2026 |
| Dilliway & Bosley Equine Veterinary Practice Ltd | Professional & scientific | 2020 |
| Dillons Design Limited | Professional & scientific | 2005 |
| Dimax Construction Ltd | Construction | 2021 |
| Dimensions for Autism C.I.C. | Other services | 2019 |
| DIMOND68 Ltd | Hospitality | 2024 |
| Dince Hill Associates Limited | Financial services | 2024 |
| Dinnis Developments Limited | Real estate | 1958 |
| Dinosaur Restaurant Ltd | Hospitality | 2019 |
| Dionilife Limited | Financial services | 2024 |
| Dionilife UK Limited | Wholesale & retail | 2024 |
| Dipland Limited | Wholesale & retail | 1988 |
| Dirac Delta Solutions Ltd | Information & communication | 2013 |
| Direct Assembly Solutions Limited | Manufacturing | 2008 |
| Direct Hygiene Supplies Ltd | Administrative & support | 2024 |
| Direct Link Accountancy Ltd | Financial services | 2016 |
| Direct Property Maintenance Ltd | Households | 2023 |
| Direct R L Limited | Wholesale & retail | 2022 |
| Direct Removals Ltd | Transport & logistics | 2026 |
| Direct Specialist Services Ltd | Construction | 2022 |
| DIRECT2DOOR Ltd | Wholesale & retail | 2022 |
| Direction and Design Limited | Extraterritorial | 2017 |
| Dirty Martini Marketing Ltd | Information & communication | 2018 |
| Disability Together Limited | Education | 2003 |
| Disco Powered Ltd | Professional & scientific | 2020 |
| Discount Surplus UK Limited | Wholesale & retail | 2011 |
| Discover Romania Ltd | Health & social care | 2019 |
| District Carpentry & Building Ltd | Manufacturing | 2022 |
| District Driveways Limited | Construction | 2025 |
| Divers Motor Company Limited | Wholesale & retail | 2004 |
| Diverse Composites Ltd | Manufacturing | 2018 |
| Diverse Devon Together CIC | Education | 2023 |
| Diverse Utilities SW Ltd | Construction | 2024 |
| Divine Casa Properties Limited | Real estate | 2018 |
| Divine Flowers & Crafts Ltd | Real estate | 2022 |
| Dixon Mental Health and Wellbeing Limited | Health & social care | 2016 |
| Dixonsmith LLP | | 2022 |
| Dizzy Otter Ltd | Information & communication | 2025 |