| Structured Commercial Finance Limited | Extraterritorial | 2021 |
| Strukko Ltd | Manufacturing | 2023 |
| STS Property Holdings Limited | Real estate | 2026 |
| STT Building Solutions Ltd | Construction | 2019 |
| Stuart Clinton Property Limited | Real estate | 2017 |
| Stuart Grant Limited | Financial services | 2022 |
| Stuart Marsh Shoes Limited | Professional & scientific | 1982 |
| Stuart Partners Limited | Agriculture & fishing | 2012 |
| Stuart Properties Limited | Construction | 2013 |
| Stuart Property (Holdings) Limited | Financial services | 2014 |
| Stuart Taylor Farrier Ltd | Agriculture & fishing | 2012 |
| Stuart.Media Ltd | Information & communication | 2015 |
| Stuarts Truck and BUS Limited | Wholesale & retail | 2014 |
| Stuck on Site Limited | Information & communication | 2023 |
| Student Digs Garden Maintenance Ltd | Administrative & support | 2026 |
| Student Record Services Limited | Information & communication | 2015 |
| Student Zone Lettings Ltd | Real estate | 2022 |
| Studio Pascoe Ltd | Professional & scientific | 2025 |
| Studio Quinn Davis Limited | Professional & scientific | 2025 |
| Studio Rage Ltd | Professional & scientific | 2022 |
| Studio Tether Limited | Professional & scientific | 2024 |
| Studiomh Limited | Professional & scientific | 2019 |
| Studley House (Wichelstowe) Management Company Limited | Households | 2025 |
| Style Messenger Ltd | Wholesale & retail | 2025 |
| Stylish Properties Ltd | Real estate | 2021 |
| Sub-Aqua Stock Ltd | Wholesale & retail | 2022 |
| Subelements Consulting Limited | Other services | 2020 |
| Subhan (Devon) Ltd | Hospitality | 2023 |
| Subplan Electronics Limited | Manufacturing | 2023 |
| Subset Network Technologies Ltd | Information & communication | 2025 |
| Subtle Improvements Electrical Contractors Limited | Construction | 2017 |
| Subversive Ltd. | Information & communication | 2011 |
| Success Solutions (Uk&I) Limited | Professional & scientific | 2023 |
| Suciu Services Ltd | Professional & scientific | 2018 |
| Sugar Rush Confectionery Ltd | Wholesale & retail | 2015 |
| Sukhahar Ltd | Hospitality | 2022 |
| Sukhjeet Singh Ltd | Construction | 2016 |
| Suki Radcliffe Holdings Limited | Professional & scientific | 2020 |
| Sulaiman Devon Ltd | Wholesale & retail | 2023 |
| Sulis & Llyr Limited | Wholesale & retail | 2017 |
| Sullivan Business Psychologists Limited | Real estate | 1999 |
| Summerfield Planning Limited | Professional & scientific | 2022 |
| Summerhill Family Investment Company Limited | Financial services | 2020 |
| Summit Contract Services Ltd | Construction | 2022 |
| Summit Motor Company Limited | Wholesale & retail | 2025 |
| Summit Tactical Ltd | Wholesale & retail | 2025 |
| Summus Property Ltd | Real estate | 2019 |
| Sumographics Ltd | Professional & scientific | 2015 |
| Sun & Belmont Ltd | Real estate | 2019 |
| Sunbeam Ecology Ltd | Professional & scientific | 2024 |
| Suncode Limited | Health & social care | 2010 |
| Sunetik Limited | Construction | 2014 |
| Sunflower Day Nurseries Limited | Education | 2014 |
| Sunflower Day Nursery LLP | | 2006 |
| Sunflower Energy Solutions Ltd | Construction | 2011 |
| Sunfresh Foods Limited | Wholesale & retail | 2016 |
| Sungift Energy Limited | Extraterritorial | 2015 |
| Sungift Limited | Extraterritorial | 2015 |
| Sungift Renewables Ltd | Extraterritorial | 2011 |
| Sungift Solar Limited | Construction | 2007 |
| Sungula Consulting Limited | Information & communication | 2022 |
| Sunhill Property Holdings Ltd | Real estate | 2026 |
| Sunny Pharma Ltd | Professional & scientific | 2014 |
| Sunny's Coffee Ltd | Hospitality | 2026 |
| SUNNYSIDE1983 Limited | Information & communication | 2015 |
| Sunrise Event Management Limited | Administrative & support | 2015 |
| Sunscape Digital Ltd | Information & communication | 2022 |
| Sunshine Care & Enabling Services Ltd | Public administration | 2025 |
| Sunshine Rentals Limited | Professional & scientific | 2014 |
| Supa Stone Ltd | Wholesale & retail | 2023 |
| Superchallenge Ltd | Wholesale & retail | 2023 |
| Supercranes South West Ltd | Transport & logistics | 2025 |
| Superdry Seals Ltd | Manufacturing | 2015 |
| Supporting Elite Coaching Ltd | Arts & recreation | 2025 |
| Supporting Neonatal Users & Graduates (Snug) Ltd | Health & social care | 2013 |
| Surf Life Saving Great Britain | Education | 1992 |
| Surplus Trade Supplies Limited | Wholesale & retail | 2010 |
| Surreal Estate 2 Ltd | Real estate | 2024 |
| Surreal Estate Developments LLP | | 2019 |
| Surreal Estate Ltd | Construction | 2019 |
| Surris Limited | Hospitality | 2021 |
| Sustain Product Development Limited | Extraterritorial | 2018 |
| Sustainable Community Solutions Limited | Professional & scientific | 2025 |
| Sustainable Ethical Holdings Limited | Energy | 2020 |
| Sustance Limited | Arts & recreation | 2020 |
| Sutton Electrical SW Ltd | Construction | 2021 |
| Suvina Limited | Other services | 2017 |
| Svdl (UK) Ltd | Transport & logistics | 2021 |
| SW Car Centre Ltd | Wholesale & retail | 2025 |
| SW Clearances & Cleans Ltd | Transport & logistics | 2022 |
| SW Firedoors Ltd | Construction | 2024 |
| SW Foam & Fibre Ltd | Other services | 2015 |
| SW Food Group Ltd | Financial services | 2022 |
| SW Food Waste Collection Ltd | Water & waste | 2025 |
| SW Property Rentals Ltd | Real estate | 2020 |
| SW Renewable Services Ltd | Construction | 2023 |
| SW Website Consulting Ltd | Information & communication | 2026 |
| SW Woodland Management Limited | Agriculture & fishing | 2022 |
| SW2MIX Ltd | Wholesale & retail | 2024 |
| SW6 Capital Ltd | Construction | 2020 |