| Swabs Developments Ltd | Construction | 2016 |
| Swabs Properties Ltd | Real estate | 2021 |
| Swag Distribution Limited | Wholesale & retail | 2012 |
| Swan Eveling Limited | Professional & scientific | 2023 |
| Swanblog Ltd | Information & communication | 2023 |
| Swanky Group Limited | Administrative & support | 2010 |
| SWC Property Solutions Ltd | Construction | 2020 |
| Swch Holdings Limited | Financial services | 2023 |
| Swch Limited | Professional & scientific | 2011 |
| Sweet Needle Studio Ltd | Other services | 2023 |
| Sweetmay Limited | Wholesale & retail | 2004 |
| Sweetp Limited | Information & communication | 2011 |
| Sweetpea Smallholdings CIC | Agriculture & fishing | 2021 |
| Swell Group UK Ltd | Professional & scientific | 2021 |
| Swift and Sure Engineering Ltd | Information & communication | 2026 |
| Swift Surfacing South West Limited | Construction | 2023 |
| Swiftelex Limited | Arts & recreation | 2025 |
| Swim Focus Ltd | Education | 2021 |
| Swimbridge Medical Consultancy Limited | Professional & scientific | 2023 |
| Swineley Conservation Limited | Real estate | 2021 |
| Switch Systems Ltd | Information & communication | 2006 |
| Swpco Ltd | Hospitality | 2023 |
| SWRUGBY7'S Limited | Arts & recreation | 2015 |
| SWS Facility Services Ltd | Administrative & support | 2016 |
| Swsystems Limited | Financial services | 2020 |
| SWW Pension Trustees Limited | Professional & scientific | 1989 |
| Sycamore Coaching Limited | Professional & scientific | 2016 |
| Sydenham House Management Limited | Households | 1982 |
| Sygone Limited | Financial services | 2021 |
| Sylvawood Agriculture Ltd | Agriculture & fishing | 2019 |
| Sylvawood Ltd | Agriculture & fishing | 2020 |
| Sylvia Irene Wright Limited | Mining & quarrying | 2024 |
| Symbios UK Limited | Wholesale & retail | 2006 |
| Symes Partnership LLP | | 2025 |
| Symmytech Ltd | Information & communication | 2023 |
| Symvoules Limited | Other services | 2014 |
| Synaptic FOX Limited | Information & communication | 2025 |
| Synchro Commercials Ltd | Manufacturing | 2021 |
| Synchro Plant Services Limited | Administrative & support | 2024 |
| Syncii Ltd | Information & communication | 2023 |
| Syndicate Research Limited | Financial services | 2014 |
| Synergetic Coaching Limited | Administrative & support | 2021 |
| Synergy Projects (SW) Limited | Construction | 2021 |
| Synergy Services Group Limited | Manufacturing | 2021 |
| Synergyvets Recruitment Ltd | Administrative & support | 2009 |
| System 6 Kitchens Limited | Manufacturing | 1985 |
| System Electrical (SW) Ltd | Construction | 2008 |
| Systemise Construction Services Ltd | Construction | 2024 |
| Systems Thinking Project Delivery Limited | Professional & scientific | 2005 |
| Syyk Limited | Real estate | 2024 |
| Szender Services Limited | Professional & scientific | 2014 |
| SZZ Trading UK Limited | Wholesale & retail | 2021 |
| T & K Groceries Ltd | Wholesale & retail | 2018 |
| T & K Piper Property Ltd | Real estate | 2026 |
| T & S (SW) Ltd | Wholesale & retail | 2019 |
| T & T Hospitality Ltd | Hospitality | 2025 |
| T Attwell Driveways Ltd | Construction | 2024 |
| T J & W Howe Limited | Wholesale & retail | 2002 |
| T J Devon Ltd | Real estate | 2020 |
| T M Whitfield General Dealers Ltd | Water & waste | 2012 |
| T Poole Ltd | Professional & scientific | 2024 |
| T R Surfacing South West Ltd | Construction | 2024 |
| T Salam Medical Services Limited | Health & social care | 2016 |
| T&O Developments Limited | Construction | 2010 |
| T&R Car Services Ltd | Wholesale & retail | 2010 |
| T&T Housing Ltd | Real estate | 2020 |
| T&Tcleans Ltd | Administrative & support | 2025 |
| T.A.M. Marketing Limited | Wholesale & retail | 1998 |
| T.G.Inns Ltd | Hospitality | 2004 |
| T.H.Ede Ltd | Real estate | 2020 |
| T2 Horizons Capital Limited | Financial services | 2025 |
| T3M1 Ltd | Real estate | 2023 |
| T7DESIGN Ltd | Wholesale & retail | 2015 |
| TA Optics Limited | Health & social care | 2017 |
| Tachyonrad Limited | Information & communication | 2022 |
| Tacoboys Ltd | Hospitality | 2019 |
| Tafika Limited | Construction | 2022 |
| TAG Plastic Extrusions Limited | Manufacturing | 1984 |
| TAG Southwest Limited | Construction | 2002 |
| Tahi Estates Ltd | Real estate | 2012 |
| Tahiya Enterprise Ltd | Transport & logistics | 2025 |
| TAI CHI Branch MA Limited | Arts & recreation | 2019 |
| Tailored Heatpump Installations Ltd | Construction | 2025 |
| Tailormade Tutors Ltd | Administrative & support | 2024 |
| Taking Time FLY Fishing Ltd | Manufacturing | 2024 |
| Talaton Building Services Limited | Hospitality | 2001 |
| Talk to Wood Ltd | Construction | 2023 |
| Tallhead Ltd | Information & communication | 2023 |
| Tally Bay Ltd | Other services | 2022 |
| Tally HO Exeter Ltd | Hospitality | 2024 |
| Tally Oak Limited | Agriculture & fishing | 2022 |
| Talon Consulting Limited | Professional & scientific | 2021 |
| Talps Holdings 2025 Ltd | Professional & scientific | 2012 |
| Talty Ltd | Professional & scientific | 2009 |
| Talzac Property Ltd | Real estate | 2011 |
| Tamar Meadows Management Company Limited | Households | 2018 |
| Tamar Roofing Ltd | Construction | 2023 |
| Tamar Security Limited | Administrative & support | 2005 |
| Tameilia Ltd | Hospitality | 2024 |
| Tamstarindian Limited | Hospitality | 2025 |