| CMP Landsol Limited | Real estate | 2019 |
| CMP Techsol Limited | Professional & scientific | 2016 |
| Coast & Country Property Ltd | Real estate | 2018 |
| Coast and Home Ltd | Construction | 2018 |
| Coastline Shellfish Limited | Agriculture & fishing | 2013 |
| Coatrans Ltd | Professional & scientific | 2014 |
| Coco Bliss Limited | Other services | 2025 |
| Colin Richardson Limited | Information & communication | 2009 |
| Colley (Farm Buildings) Limited | Construction | 1992 |
| Colley Contracting Limited | Agriculture & fishing | 2015 |
| Colley Holdings Limited | Financial services | 2025 |
| Colliewobbles Ltd | Wholesale & retail | 2009 |
| Collins Care UK Ltd | Administrative & support | 2016 |
| Comfrey Farm Holdings Ltd | Financial services | 2025 |
| Comfrey Farm Ltd | Wholesale & retail | 2022 |
| Complete Asset Management Limited | Financial services | 2001 |
| Complexbrickworx Ltd | Construction | 2026 |
| Connectias Industrial Automation Systems Ltd. | Professional & scientific | 2017 |
| Consac Services Limited | Professional & scientific | 2020 |
| Constellation Fundraising Ltd | Professional & scientific | 2024 |
| Construction Supervision Services Limited | Construction | 2002 |
| Control Solutions & Pipework Services Limited | Administrative & support | 2006 |
| Cooks Car & Van Sales Limited | Wholesale & retail | 2000 |
| Cooper Agritech Limited | Wholesale & retail | 2020 |
| Coopersbars Ltd | Hospitality | 2021 |
| Cornelian Carpets and Flooring Ltd | Construction | 2025 |
| Cornstars Catering Ltd | Hospitality | 2024 |
| Cosmic & Elvis Gifts Limited | Wholesale & retail | 2008 |
| Cotswold 1999 Pension Trustees Ltd | Other services | 2021 |
| Country GAS Limited | Energy | 2003 |
| Courtyard Cafe 1864 Limited | Hospitality | 2023 |
| Coutts Property Developments Ltd | Real estate | 2025 |
| CP Martin Ltd | Administrative & support | 2012 |
| Cphas Ltd | Information & communication | 2026 |
| Cpwaring Ltd | Wholesale & retail | 2020 |
| Cranswick Caravan Storage Limited | Real estate | 2006 |
| Cranwell Medical Developments Limited | Health & social care | 2010 |
| Crest House Properties LLP | | 2023 |
| Crimsworth Road Management Company Limited | Households | 1998 |
| Crooked Dale Eggs Limited | Agriculture & fishing | 2011 |
| Crown Training Academy Ltd | Education | 2025 |
| Crowthers (Ripponden) Limited | Professional & scientific | 2009 |
| Crowthers Limited | Agriculture & fishing | 2005 |
| Cryo Noir Limited | Information & communication | 2016 |
| Ctfm Service Ltd | Manufacturing | 2024 |
| Custom Financial Services Limited | Financial services | 2003 |
| Custom Homes Solutions Limited | Professional & scientific | 2012 |
| Cyber Programme Solutions Ltd | Information & communication | 2025 |
| D & J Woodcock Limited | Wholesale & retail | 2003 |
| D & R Consultancy Ltd | Professional & scientific | 2016 |
| D & S Importers (Yorkshire) Ltd | Wholesale & retail | 2025 |
| D & S Nicholson & Sons Ltd | Agriculture & fishing | 2016 |
| D a Rodgers Limited | Transport & logistics | 2014 |
| D E Byass and SON Ltd | Agriculture & fishing | 2012 |
| D Hope Engineering Services Limited | Professional & scientific | 2015 |
| D J Brent Limited | Construction | 2015 |
| D P Morgan | Agriculture & fishing | 2000 |
| D Pemberton & Sons Limited | Wholesale & retail | 2022 |
| D Shotton Transport Ltd | Transport & logistics | 2018 |
| D Wilks & Co Limited | Wholesale & retail | 1999 |
| D.G. Taylor Commercial Vehicles Limited | Wholesale & retail | 1978 |
| Dacre Pigs Limited | Agriculture & fishing | 1994 |
| Dahero Limited | Professional & scientific | 2021 |
| Daleream Limited | Wholesale & retail | 2001 |
| Dane Tyas Construction Limited | Construction | 2021 |
| Darl Limited | Real estate | 2022 |
| Darta UK Ltd | Wholesale & retail | 2003 |
| Darta Yorkshire Ltd | Manufacturing | 2017 |
| Dave's Driving School Ltd | Education | 2025 |
| David Cooper Blacksmiths Limited | Manufacturing | 2009 |
| David Jibson Agricultural Contractor Limited | Agriculture & fishing | 2012 |
| Davies Kitchens Ltd | Construction | 2022 |
| Dawber Williamson Ceilings Limited | Construction | 2009 |
| Dawsons Interiors Ltd | Construction | 2020 |
| Dayn Properties Ltd | Construction | 2022 |
| DB Autotech (Driffield) Ltd | Wholesale & retail | 2016 |
| DB Engineering Management Yorkshire Limited | Professional & scientific | 2010 |
| DC2AC Ltd | Wholesale & retail | 2025 |
| Dead DUK Limited | Wholesale & retail | 2020 |
| Defence Assets Ltd | Manufacturing | 2010 |
| Delahaye Moving Limited | Transport & logistics | 1979 |
| Demraview Limited | Construction | 2001 |
| Denis Woodmansey Limited | Construction | 2007 |
| Dermaesthetics Limited | Other services | 2015 |
| Devlin (Lincs) Limited | Construction | 2003 |
| Dewhirst Group Limited | Professional & scientific | 1972 |
| Dewhirst Overseas Limited | Professional & scientific | 1995 |
| Dewhirst Properties Limited | Extraterritorial | 1990 |
| Dexecom Ltd | Professional & scientific | 2019 |
| Digital Bridge Communications Limited | Professional & scientific | 2014 |
| Digital Entrepreneur Limited | Information & communication | 2010 |
| Direct Cleaning & Hygiene Supplies Ltd | Wholesale & retail | 2003 |
| Direct Imaging Supplies Limited | Wholesale & retail | 2009 |
| Direct Tool & Plant Hire Ltd | Administrative & support | 2024 |
| Disability First AID Ltd | Administrative & support | 2026 |
| Dixon Bloodstock Limited | Arts & recreation | 2018 |
| Diyacrylic Trade Limited | Wholesale & retail | 2025 |
| DMQ Consultancy Limited | Professional & scientific | 2012 |
| DMS Holistic Ltd | Health & social care | 2022 |
| DMS Kilham Ltd | Administrative & support | 2016 |