| Boss Socials Ltd | Professional & scientific | 2025 |
| Botterill Farms Limited | Agriculture & fishing | 2015 |
| Boxenvi Ltd | Extraterritorial | 2023 |
| Bracken Construction (East Yorkshire) Limited | Construction | 2017 |
| Bradbury & Co (Accountants) Limited | Professional & scientific | 2007 |
| Bradonwood Limited | Agriculture & fishing | 2002 |
| Brambles Construction Services Limited | Professional & scientific | 2009 |
| Branham Farming Limited | Agriculture & fishing | 2011 |
| BRD Distributions Ltd | Wholesale & retail | 2026 |
| Breeze Farm Holiday Cottages Ltd | Hospitality | 2020 |
| Bridge Farm Holiday Cottages Limited | Hospitality | 2024 |
| Bridge Street Dental Ltd | Health & social care | 2014 |
| Bridlington Finance Limited | Financial services | 2021 |
| Bright Hill Property Ltd | Real estate | 2025 |
| Brighten Care Ltd | Extraterritorial | 2020 |
| Broachdale Birds Limited | Agriculture & fishing | 2005 |
| Brookenby Research Limited | Wholesale & retail | 2008 |
| Broughton 2024 Limited | Hospitality | 2000 |
| Burdett Asset Management Ltd | Real estate | 2025 |
| Burdett Civils Ltd | Construction | 2022 |
| Burghcliffe Court Management Company Limited | Households | 1997 |
| Burton Agnes Hall Preservation Trust Limited | Arts & recreation | 1977 |
| Burton Agnes Hall Trading Limited | Wholesale & retail | 2008 |
| Burton Agnes Stud Company Limited(The) | Agriculture & fishing | 1962 |
| Business Plus Web Ltd | Information & communication | 2012 |
| BY Ashley Dean Limited | Information & communication | 2023 |
| Byford Developments Limited | Real estate | 2005 |
| C & J Wilson Limited | Construction | 2002 |
| C & L (Yorkshire) Limited | Transport & logistics | 2014 |
| C & S Aromatics Limited | Wholesale & retail | 2010 |
| C N Warkup & Sons (Pigs) Limited | Agriculture & fishing | 2010 |
| C P Vaudin Limited | Manufacturing | 2001 |
| C R & J Booth Limited | Construction | 2025 |
| C W Foreman Limited | Agriculture & fishing | 2013 |
| C&G Engineering and Ventilation Ltd | Manufacturing | 2023 |
| C&K Property Solutions Ltd | Real estate | 2019 |
| C-Fret Festival Limited | Manufacturing | 2022 |
| C.C Agricultural Consultants Ltd | Professional & scientific | 2025 |
| C.J Nursery Ltd | Education | 2024 |
| C.R.H. Medical Training Limited | Professional & scientific | 2000 |
| Cafe Norah Driffield Ltd | Hospitality | 2025 |
| Caflin Limited | Households | 2016 |
| Calcora Ltd | Professional & scientific | 2026 |
| Calden Marine Limited | Construction | 2012 |
| Calderas Consulting Ltd | Professional & scientific | 2026 |
| Candy Confectionery and Gifts Limited | Wholesale & retail | 2017 |
| Caravan Care Plan Ltd | Other services | 2026 |
| Caravan Trading Solutions Limited | Wholesale & retail | 2012 |
| Care 2 I Community Interest Company | Health & social care | 2016 |
| Care Oncology Ltd | Health & social care | 2010 |
| Carn Rock QA Ltd | Professional & scientific | 2021 |
| Carnaby Consulting Limited | Professional & scientific | 2019 |
| Carnworth (Eight) Limited | Construction | 2021 |
| Carnworth (Seven) Limited | Construction | 2021 |
| Carpvale Fisheries (NO.1) Ltd | Agriculture & fishing | 2021 |
| Carr House Farm Limited | Agriculture & fishing | 2004 |
| Carr House Property Ltd | Real estate | 2025 |
| Carr Lane Kennels Limited | Agriculture & fishing | 2006 |
| Cartridges Online Limited | Wholesale & retail | 2023 |
| Catfoss Cabin Hire Limited | Administrative & support | 2012 |
| Catfoss Caravan Storage Ltd | Transport & logistics | 2001 |
| Catfoss Colchester Limited | Construction | 2018 |
| Catfoss DBT Limited | Extraterritorial | 2018 |
| Catfoss Enterprises Limited | Financial services | 2022 |
| Catfoss Finance Limited | Financial services | 2001 |
| Catfoss Industrial Holdings Limited | Financial services | 2023 |
| Catfoss Investments Limited | Financial services | 2018 |
| Catfoss Modular Hire Limited | Construction | 2008 |
| Catfoss Northampton Limited | Construction | 2018 |
| Catfoss P1 Limited | Financial services | 2023 |
| Catfoss P2 Limited | Financial services | 2023 |
| Catfoss P5 Limited | Financial services | 2023 |
| Catfoss Poole Limited | Construction | 2018 |
| Cavendish Contemporary Limited | Wholesale & retail | 2021 |
| Cavendish Stone Ltd | Manufacturing | 2005 |
| Cawkeld Farming Limited | Agriculture & fishing | 1954 |
| CB Holdings Driffield Limited | Real estate | 2014 |
| CB Solutions U.K. Ltd | Manufacturing | 2000 |
| CB Vitamins Limited | Wholesale & retail | 2025 |
| CDA Resourcing Limited | Other services | 2018 |
| Central Computers (Driffield) Ltd | Wholesale & retail | 2018 |
| Central Employee Services Consultancy Ltd | Professional & scientific | 2018 |
| Champagne Cottage Ltd | Real estate | 2026 |
| Chapel Moor Pet Cremation Services Limited | Other services | 2003 |
| Charles Edward Building Services Limited | Wholesale & retail | 2024 |
| Chatterton Estates Limited | Real estate | 2016 |
| Chbg Limited | Financial services | 2020 |
| Cheeky Chappy (Driffield) Ltd | Information & communication | 2024 |
| Cherrypod Property Management Ltd | Households | 2020 |
| Chris Atkinson (Nafferton) Limited | Manufacturing | 1972 |
| Chris Gray Ltd | Construction | 2007 |
| Christie Private Client Limited | Professional & scientific | 2009 |
| Christopher Nelmes Ltd | Information & communication | 2016 |
| Chrysalis Case Management Ltd | Other services | 2016 |
| CJA Investments Ltd | Real estate | 2016 |
| Claire Wilson Consulting Limited | Other services | 2012 |
| Classic Rugby Shirts Limited | Wholesale & retail | 2012 |
| Clear Air Solutions Limited | Administrative & support | 2011 |
| Clifton Timber Limited | Wholesale & retail | 1997 |
| Clive Soanes (Broilers) Ltd. | Agriculture & fishing | 1986 |