| Solar Energy Maximiser Limited | Professional & scientific | 2012 |
| Solaris Engineering Limited | Professional & scientific | 2026 |
| Solaris Global Engineering Limited | Professional & scientific | 2026 |
| Sola’S Kitchen Ltd | Hospitality | 2025 |
| Solcast Consultants Ltd | Construction | 2017 |
| Sole Relax Studio Ltd | Other services | 2025 |
| Solease Ltd | Health & social care | 2014 |
| Solebar Ltd | Professional & scientific | 2019 |
| Solex Engineering Solutions Ltd | Professional & scientific | 2006 |
| Solid Group Holdings Limited | Financial services | 2019 |
| Solid Rock Group Ltd | Education | 2024 |
| Solid Rock Housing Limited | Real estate | 2021 |
| Solid Rock Ventures Ltd | Administrative & support | 2012 |
| Solid Systems Limited | Information & communication | 2005 |
| Solidpoint Limited | Professional & scientific | 2015 |
| Solo Bear Limited | Wholesale & retail | 2021 |
| Solo Martial Arts Limited | Arts & recreation | 2006 |
| Solortech Limited | Construction | 2023 |
| Solortus Limited | Construction | 2020 |
| Solsta Home Buyers Ltd | Real estate | 2025 |
| Solsta Investments Ltd | Financial services | 2025 |
| Solsta Turnkey Homes Ltd | Real estate | 2025 |
| Solution Accounting Ltd | Professional & scientific | 2018 |
| Solution Facilities Management Ltd | Administrative & support | 2022 |
| Solution Matrix Limited | Information & communication | 2020 |
| Solutionist Consultancy Ltd | Professional & scientific | 2018 |
| Solutions Assist Limited | Information & communication | 2020 |
| Solvedsolutions Limited | Professional & scientific | 2025 |
| Somat Ltd | Real estate | 2026 |
| Somersgate (Repton) Management Company Limited | Households | 2015 |
| Sondev Ltd | Real estate | 2024 |
| Sondhi Realty & Investments Ltd | Real estate | 2024 |
| Sonic Balance Limited | Information & communication | 2012 |
| Sonik Transport Ltd | Transport & logistics | 2024 |
| Sonikem Limited | Wholesale & retail | 2013 |
| Sonoran Rovers UK Limited | Wholesale & retail | 2020 |
| Sood INT Ltd | Wholesale & retail | 2025 |
| Sophie Road Management Ltd | Households | 2007 |
| Sora Padel Limited | Arts & recreation | 2026 |
| Sorberus Limited | Professional & scientific | 2026 |
| Sort Group Limited | Financial services | 2015 |
| Sort Legal Limited | Professional & scientific | 2016 |
| Sort Limited | Administrative & support | 2009 |
| SOS Bookkeeping Limited | Professional & scientific | 2015 |
| SOS Lingerie Limited | Wholesale & retail | 2020 |
| Souden Ltd | Construction | 2004 |
| Souldeep Ltd | Information & communication | 2003 |
| Soulful Creation Intuitive Design Ltd | Arts & recreation | 2025 |
| Soulyman Property Limited | Real estate | 2026 |
| Sound Electrical Services Ltd. | Construction | 2024 |
| Sound of Music Limited | Administrative & support | 2002 |
| Sound Perspective Limited | Arts & recreation | 2008 |
| Soundgas Limited | Manufacturing | 2013 |
| Soundhealth Ltd | Health & social care | 2014 |
| Soundhealth Training Limited | Education | 2024 |
| Source by FM Ltd | Wholesale & retail | 2025 |
| Source Recruitment Group Limited | Administrative & support | 2014 |
| Source UN Limited | Information & communication | 2013 |
| South Corner (Derby) Management Company Limited | Real estate | 2005 |
| South Derbys Electrical Limited | Manufacturing | 2008 |
| South Derbyshire Karate Academy Ltd | Education | 2020 |
| South Notts Construction Ltd | Construction | 2024 |
| South Ockendon Residents Management Company Limited | Households | 2014 |
| South View Indexing and Paper Products Limited | Manufacturing | 1980 |
| Southam Retail UK Limited | Wholesale & retail | 2025 |
| Southbank Property Ltd | Real estate | 2021 |
| Southbourne Fields Residents Management Company Limited | Households | 2018 |
| Southcrest Rise Residents Management Company Limited | Households | 2023 |
| Southern Cross Ltd | Transport & logistics | 2015 |
| Southkey Holdings Ltd | Wholesale & retail | 2023 |
| Southkey Living Ltd | Real estate | 2024 |
| Souwek Ltd | Wholesale & retail | 2025 |
| Sovereign Audiovisual Limited | Extraterritorial | 2010 |
| Sovereign Crest Commercial Ltd | Real estate | 2022 |
| Sovereign Crest Investments Limited | Professional & scientific | 2019 |
| Sovereign Crest Limited | Construction | 2004 |
| Sovereign Crest Property Limited | Construction | 2025 |
| Sovereign Events (UK) Limited | Hospitality | 2021 |
| Sovereign Park Residents Management Company Limited | Households | 2017 |
| Sovereign Windows, Doors & Conservatories Limited | Construction | 2014 |
| SOZ Property Ltd | Real estate | 2025 |
| SP 0718 Limited | Real estate | 2018 |
| SP 225 Limited | Manufacturing | 2016 |
| SP Electrical Contracting Services Ltd | Construction | 2026 |
| SP Nature Link Co. Ltd | Wholesale & retail | 2018 |
| SP Service and Repair Ltd | Wholesale & retail | 2019 |
| SP Tree Consultancy Limited | Agriculture & fishing | 2019 |
| Spa Diamond Derby Limited | Health & social care | 2015 |
| Spa Finishing School Ltd | Administrative & support | 2025 |
| Spa Web Limited | Manufacturing | 1963 |
| Space Cat Lettings Ltd | Construction | 2025 |
| Space TI Ltd | Professional & scientific | 2024 |
| SPACE360 Ltd | Construction | 2018 |
| Spacebass Studios Ltd | Information & communication | 2018 |
| SPACES@360 Ltd | Professional & scientific | 2024 |
| Spagetti Ltd | Information & communication | 2015 |
| Spal Properties Limited | Real estate | 2025 |
| Spalding Strength Ltd | Arts & recreation | 2019 |
| Spanner Software Limited | Information & communication | 1998 |
| Spark & Spectrum CIC | Education | 2026 |