| Smith & Loadman Holdings Ltd | Professional & scientific | 2024 |
| Smith Apparel Ltd | Wholesale & retail | 2026 |
| Smith Cooper Audit Services Holdings Limited | Professional & scientific | 2018 |
| Smith Kennedy Limited | Professional & scientific | 2004 |
| Smith of Derby (INT) Limited | Manufacturing | 2012 |
| Smith Site Services Limited | Manufacturing | 2020 |
| Smithflint Associates Limited | Professional & scientific | 2017 |
| Smiths (Solicitors) LLP | | 2013 |
| Smiths Accountancy Administration Services Ltd | Professional & scientific | 2020 |
| Smiths Composite Services Ltd | Manufacturing | 2024 |
| Smiths Composites Ltd | Manufacturing | 2018 |
| Smiths Decorators Derby Ltd. | Construction | 2017 |
| Smiths International Plumbing & Heating Ltd. | Construction | 1995 |
| Smiths Surfacing Ltd | Construction | 2026 |
| Smithwood Properties Ltd | Real estate | 2025 |
| SML Homes Ltd | Real estate | 2020 |
| SMM Assets Ltd | Real estate | 2024 |
| SMN Investment Limited | Health & social care | 2021 |
| SMN Property Services Ltd | Real estate | 2025 |
| SMO Healthcare Limited | Professional & scientific | 2021 |
| Smoothvault Moves Ltd | Transport & logistics | 2026 |
| SMR 22 Ltd | Financial services | 2022 |
| SMS Medical & Ambulance Solutions Ltd | Administrative & support | 2018 |
| Smsa Healthcare Limited | Health & social care | 2025 |
| Smsk Silk Ltd | Wholesale & retail | 2026 |
| SMT Professional Services Limited | Information & communication | 2014 |
| Smurefu&Sons Limited | Health & social care | 2025 |
| SMV Distribution Ltd | Transport & logistics | 2020 |
| SMV Express Ltd | Transport & logistics | 2025 |
| SN Property Enterprise Ltd | Real estate | 2026 |
| SN1 Limited | Hospitality | 2015 |
| SNA Repairs Ltd | Wholesale & retail | 2022 |
| SNA Vehicle Hire Ltd | Administrative & support | 2025 |
| Snack City UK Ltd | Wholesale & retail | 2022 |
| Snake PC and Customs Limited | Manufacturing | 2025 |
| Snap Developments Ltd. | Construction | 2013 |
| Snap Recruitment Ltd | Administrative & support | 2020 |
| Snapcandy Photo Booths Limited | Professional & scientific | 2015 |
| Snape Management Limited | Professional & scientific | 2012 |
| Snapfulfil Limited | Information & communication | 2016 |
| Snapgetsolutions Ltd | Administrative & support | 2025 |
| Snapshot Software Limited | Information & communication | 2015 |
| Snibston Mill Estate Management Company Limited | Households | 2023 |
| Snipehill Limited | Professional & scientific | 2013 |
| SNK Driving School Ltd | Education | 2025 |
| Snkr Ltd | Construction | 2025 |
| Snowbird Foods Enfield Limited | Construction | 2017 |
| Snowdon Sports Media Partners Limited | Information & communication | 2002 |
| Snowflakes Properties Limited | Real estate | 2021 |
| SNR Renewables Limited | Energy | 2024 |
| SNS Recruitment and Services Ltd | Construction | 2024 |
| Snug Media Limited | Arts & recreation | 2006 |
| SO Cheung Properties Ltd | Real estate | 2023 |
| SO Estate Ltd | Real estate | 2025 |
| SO Shelley.Socials Limited | Professional & scientific | 2023 |
| SO Spotless Cleaning Ltd | Administrative & support | 2025 |
| SO Streetworks Ltd | Construction | 2020 |
| Soap & Pawrey Pamper Pooch Emporium Limited | Administrative & support | 2021 |
| Soapbox 65 Marketing Limited | Professional & scientific | 2016 |
| Soapie Coats Ltd | Administrative & support | 2026 |
| Soapy Joey Limited | Administrative & support | 2025 |
| Sobmar Ltd | Transport & logistics | 2017 |
| Sobuj Limited | Hospitality | 2021 |
| Socal&Deanos Ltd | Administrative & support | 2025 |
| Soccer Stars UK Limited | Education | 2003 |
| Social Bait Limited | Professional & scientific | 2022 |
| Social Barter UK Ltd | Wholesale & retail | 2016 |
| Social Impact Ltd | Professional & scientific | 2014 |
| Social Media London Ltd | Administrative & support | 2012 |
| Social Moody Ltd | Professional & scientific | 2023 |
| Social Ventures Partnership C.I.C. | Professional & scientific | 2024 |
| Social Xcommerce Ltd | Wholesale & retail | 2025 |
| Socialbox Ltd | Information & communication | 2016 |
| Socks N' Stuff Limited | Wholesale & retail | 2003 |
| Socotra Logistics UK Limited | Transport & logistics | 2013 |
| Socotraxpress Ltd. | Transport & logistics | 2015 |
| Soda Business Development Limited | Professional & scientific | 2019 |
| Soen Construction Limited | Construction | 2025 |
| Soen Holdings Limited | Financial services | 2025 |
| Soen Investments Limited | Real estate | 2026 |
| Soesibbs Ltd | Health & social care | 2026 |
| Sofia Trading Ltd | Wholesale & retail | 2026 |
| Sofpc Limited | Real estate | 2026 |
| Soft Innovation Limited | Information & communication | 2022 |
| Softhand Home of Beauty Ltd | Other services | 2026 |
| Softislands Ltd | Information & communication | 2021 |
| Software Informatics Limited | Information & communication | 2011 |
| Software Licence Consulting Ltd | Information & communication | 2016 |
| SOFTWARE4CONTRACTORS Limited | Information & communication | 2014 |
| Softy Ltd | Information & communication | 2016 |
| Sohan Builder Ltd | Construction | 2026 |
| Sohorace Limited | Administrative & support | 2011 |
| Sohosoletrade Co., Ltd | Wholesale & retail | 2026 |
| Soiree Luxe Events Ltd | Hospitality | 2025 |
| Soka Care Services Ltd | Health & social care | 2021 |
| Soko Social Care Services Ltd | Health & social care | 2025 |
| SOL Trucks and Machinery Export Ltd | Wholesale & retail | 2015 |
| SOL3T Ltd | Health & social care | 2019 |
| Solace and AOV Ltd | Information & communication | 2022 |
| Solana Homes Limited | Real estate | 2025 |