| Donaldson Investments Limited | Real estate | 2010 |
| Donato Investments Limited | Financial services | 2022 |
| Donna Freeman Consultancy Limited | Administrative & support | 2006 |
| Donnan-Smith Limited | Wholesale & retail | 2010 |
| Donnington Brewery Limited | Manufacturing | 2017 |
| Donovan Property Holdings Limited | Real estate | 2019 |
| Donovan's Dental Practice Limited | Health & social care | 2010 |
| Door 4 Montpellier Limited | Hospitality | 2016 |
| Door Doctor (South West) Limited | Professional & scientific | 2014 |
| Doorbox Ltd | Wholesale & retail | 2010 |
| Dopano Group Holdings Limited | Financial services | 2022 |
| Dopano Limited | Professional & scientific | 2006 |
| Doral Systems Limited | Professional & scientific | 2026 |
| Doran Court (Ealing) Freehold Company Limited | Households | 1986 |
| Dorchester Court Management Company Limited | Households | 1997 |
| Dormay Management Limited | Households | 2012 |
| Dorset Freedom Properties Limited | Real estate | 2014 |
| Dorstone Agroforestry Limited | Agriculture & fishing | 2024 |
| Dosa Station Ltd | Hospitality | 2025 |
| Dosego Limited | Wholesale & retail | 2013 |
| DOT DOT Boyes Ltd | Real estate | 2024 |
| DOT on I Ltd | Wholesale & retail | 2020 |
| Dotacinema Ltd | Information & communication | 2014 |
| Dotty Cotton Limited | Wholesale & retail | 2026 |
| Double 'R' Farm 2004 Limited | Professional & scientific | 2004 |
| Double 'R' Farm Company Limited | Agriculture & fishing | 1979 |
| Douro Holdings Limited | Construction | 2007 |
| Douro House (Cheltenham) Management Company Limited | Households | 1982 |
| Douro Limited | Construction | 2009 |
| Dovepark Estates Limited | Real estate | 2002 |
| Dowdeswell Aviation LLP | | 2013 |
| Dowdeswell Conservation (Trading) Limited | Agriculture & fishing | 2021 |
| Dowdeswell Conservation Limited | Agriculture & fishing | 2014 |
| Dowdeswell Court Limited | Professional & scientific | 2017 |
| Dowdeswell Equestrian LLP | | 2022 |
| Dowdeswell Forestry Limited | Agriculture & fishing | 2017 |
| Dowdeswell Padel Limited | Arts & recreation | 2025 |
| Dowdeswell Park (Estates) LLP | | 2019 |
| Dowdeswell Park Limited | Professional & scientific | 2016 |
| Dowdeswell Residential (London and Cotswolds) Limited | Construction | 2013 |
| Dowlais Top Wind Limited | Energy | 2023 |
| Down Under Centre Limited | Administrative & support | 2013 |
| Downchapel Engineering Ltd | Professional & scientific | 2025 |
| Downshift Autos Ltd | Wholesale & retail | 2024 |
| Downshire Homes Limited | Public administration | 2015 |
| DP Animal Services Ltd | Professional & scientific | 2019 |
| DP Carpentry and Building Limited | Construction | 2024 |
| DPM IT Solutions Ltd | Information & communication | 2011 |
| DPO Group Ltd | Professional & scientific | 2024 |
| DPO Utilities Ltd | Construction | 2024 |
| Dpsc Limited | Professional & scientific | 2015 |
| DPX Probuild Ltd | Construction | 2025 |
| Dqadams Consultancy Limited | Professional & scientific | 2023 |
| DQM Solutions Ltd | Professional & scientific | 2011 |
| DR a Raghuram Limited | Health & social care | 2020 |
| DR Adam RYE Limited | Health & social care | 2019 |
| DR Arora Medical Aesthetics Ltd | Health & social care | 2024 |
| DR Brown Oncology Ltd | Health & social care | 2022 |
| DR D Farrugia Ltd | Health & social care | 2011 |
| DR M Islam Limited | Health & social care | 2012 |
| DR Mark Pearce Ltd | Health & social care | 2015 |
| DR William REA Ltd | Health & social care | 2019 |
| DR Zeenat Vishal Bhalla Limited | Health & social care | 2016 |
| DR16729 Limited | Real estate | 2011 |
| DRA Home Improvements Ltd | Construction | 2022 |
| Draggetts Limited | Real estate | 2016 |
| Dragon FLY Takeaway Limited | Hospitality | 2013 |
| Drain Flow Reactive Ltd | Construction | 2019 |
| Drake Investment Company Ltd | Financial services | 2021 |
| Drakelow DC Limited | Information & communication | 2025 |
| Drakelow NG Limited | Energy | 2023 |
| Dramatic Improvement & Development Limited | Professional & scientific | 2013 |
| Drawbell Property Management Limited | Households | 1984 |
| DRB Partners Ltd | Financial services | 2021 |
| Drctta Ltd | Professional & scientific | 2016 |
| DRE (BUG) Limited | Arts & recreation | 2023 |
| Dream Challenges Limited | Administrative & support | 2011 |
| Dream Home 4U Ltd | Construction | 2010 |
| Dream House Sleep Consultancy Ltd | Health & social care | 2023 |
| Dreamy Lengths Limited | Other services | 2019 |
| Dried & Tied Flowers Limited | Wholesale & retail | 2022 |
| Driftea Ltd | Wholesale & retail | 2024 |
| Driftnet Ltd | Information & communication | 2024 |
| Driftwood Vans Ltd | Manufacturing | 2026 |
| Drill Software Limited | Information & communication | 2024 |
| Drinks Fellows Limited | Other services | 2017 |
| Drinks Hub Ltd | Professional & scientific | 2020 |
| Drinks to Market Solutions Limited | Professional & scientific | 2018 |
| Drinkwater Structural Engineers Ltd | Construction | 2014 |
| Drivecrate Ltd | Wholesale & retail | 2019 |
| Drivelease Ltd | Wholesale & retail | 2004 |
| Driver Agency Cheltenham Ltd | Transport & logistics | 2023 |
| Driver Skills Academy Ltd | Transport & logistics | 2007 |
| Drivesmart Hire Ltd | Administrative & support | 2008 |
| DRL Property Maintenance Ltd | Real estate | 2023 |
| Droning on Ltd | Professional & scientific | 2025 |
| Drop Industries Limited | Information & communication | 2025 |
| DRS Financial Services Ltd | Financial services | 2015 |
| Drshp Ltd | Health & social care | 2022 |
| Drummond House (Management) Limited | Households | 1981 |