| Digital Etimes Limited | Wholesale & retail | 2007 |
| Digital Interiors Limited | Wholesale & retail | 2006 |
| Digital Lychee Creative Limited | Information & communication | 2023 |
| Digital Meadow Ltd | Professional & scientific | 2025 |
| Digital Medical Systems Ltd | Health & social care | 2016 |
| Digital Outreach Ltd | Professional & scientific | 2025 |
| Digital Transformation & Advisory Services Ltd | Information & communication | 2022 |
| Digitally Driven Consultancy Ltd | Information & communication | 2022 |
| Digitel (UK) Holdings Limited | Financial services | 2020 |
| Digitel (UK) Limited | Professional & scientific | 2014 |
| Digivante Holdings Limited | Professional & scientific | 2018 |
| Digivante Limited | Information & communication | 2011 |
| Dikler Gorse Lake Limited | Professional & scientific | 1997 |
| Diligent Medical Ltd | Other services | 2019 |
| Dilliwala's Ltd | Hospitality | 2020 |
| Dillon Aviation Services Ltd | Transport & logistics | 2023 |
| Dimartash LLP | | 2007 |
| Dimensions Festival Limited | Arts & recreation | 2020 |
| Dimitrios Research Limited | Information & communication | 2014 |
| Dimonash Consulting Ltd | Information & communication | 2025 |
| Dinc Catering Ltd | Hospitality | 2023 |
| Dinlinch International UK Limited | Wholesale & retail | 2022 |
| Dinovate Limited | Administrative & support | 2025 |
| Dinvest (Holdings) LLP | | 2015 |
| DIP in the Pond Landscapes Limited | Administrative & support | 2019 |
| Direc-Tec Ltd | Information & communication | 2018 |
| Direct Current Residential Ltd | Real estate | 2015 |
| Direct Handling Solutions Limited | Manufacturing | 2011 |
| Direct Independent Financial Consultants Ltd | Professional & scientific | 2013 |
| Direct Linen Services | | 1996 |
| Direct Sales Limited | Wholesale & retail | 2002 |
| Directing Success Limited | Professional & scientific | 1994 |
| Directive Solutions Limited | Information & communication | 1995 |
| Dirk Malzahn Ltd | Information & communication | 2014 |
| Dirty TAN Limited | Other services | 2022 |
| DIS Administration Limited | Professional & scientific | 2017 |
| DIS Health and Fitness Limited | Health & social care | 2024 |
| DIS Sprinklers Limited | Public administration | 1905 |
| Disaster Recovery Technologies Ltd | Information & communication | 2015 |
| Disco Direct Limited | Administrative & support | 2014 |
| Discover Ceylon Limited | Wholesale & retail | 2017 |
| Discover Memsahib Limited | Hospitality | 2018 |
| Disruption Network Ltd | Professional & scientific | 2024 |
| Disruptum Limited | Information & communication | 2014 |
| Distinction Homes Property Development Limited | Construction | 2014 |
| Ditchling Mot's Limited | Wholesale & retail | 2014 |
| Dive 90 Limited | Wholesale & retail | 1998 |
| Dive 90 Training Limited | Wholesale & retail | 2001 |
| Diverse Prime Holdings Limited | Health & social care | 2021 |
| Dixie DOT Ltd | Wholesale & retail | 2024 |
| Dixon Trading Limited | Wholesale & retail | 2018 |
| Dizzy Fish International Ltd | Wholesale & retail | 2020 |
| DJ Parker Tiling Limited | Construction | 2022 |
| DJ Software Projects Limited | Professional & scientific | 2010 |
| DJB Technical Services Ltd | Information & communication | 2019 |
| DJK Projects Ltd | Construction | 2010 |
| DJL Fabrication Limited | Manufacturing | 2012 |
| DJS Lloydloom Limited | Wholesale & retail | 2021 |
| Djurni Consulting Ltd | Information & communication | 2021 |
| DK Art & Design Ltd | Administrative & support | 2003 |
| DK Digital Services Limited | Information & communication | 2015 |
| DKH Retail Limited | Wholesale & retail | 2009 |
| DKS Healthcare Ltd | Wholesale & retail | 2026 |
| DLB Electrical Services Ltd | Construction | 2013 |
| DLB Investments Ltd | Real estate | 2018 |
| DLB Plumbing and Heating Ltd | Construction | 2020 |
| DLF Properties Limited | Real estate | 2017 |
| DLH Property Management Ltd | Households | 2022 |
| DLK Quality Property Ltd | Real estate | 2026 |
| DLM Portfolio Management Ltd | Real estate | 2020 |
| DLM Wealth Management LLP | | 2015 |
| Dlsr Properties Ltd | Real estate | 2014 |
| DM Goswell Promotions Limited | Professional & scientific | 2017 |
| DM Plant Inspections Ltd | Manufacturing | 2024 |
| Dmem Investments Ltd | Financial services | 2026 |
| Dmge Ltd | Construction | 2010 |
| DMH (Bristol) Ltd | Construction | 2006 |
| DMK Advisory Limited | Arts & recreation | 2025 |
| Dmlh Consulting Limited | Information & communication | 2026 |
| DMR Project Consultancy Limited | Professional & scientific | 2014 |
| DNA Staffing Solutions Limited | Public administration | 2020 |
| DNA UK Holdings Ltd | Financial services | 2025 |
| Dna-Rb Limited | Administrative & support | 2011 |
| Dnahub Ltd | Information & communication | 2022 |
| DNJ Services Ltd | Professional & scientific | 2023 |
| DNS Grocery Limited | Wholesale & retail | 2025 |
| Doctors INK LLP | | 2023 |
| Dodwells (Cheltenham) Limited | Wholesale & retail | 2011 |
| Doedi Melvin Limited | Professional & scientific | 2000 |
| Dog & Drive International Ltd | Manufacturing | 2025 |
| Dog in the City Limited | Other services | 2024 |
| Dog&Drive Ltd | Wholesale & retail | 2026 |
| Dolly Custard Ltd | Wholesale & retail | 2018 |
| Dolly DO Ltd | Arts & recreation | 2021 |
| Domijontes Limited | Wholesale & retail | 2025 |
| Dominic Dore Property Limited | Real estate | 2023 |
| Dominiques Beauty Ltd | Other services | 2021 |
| Domsea Limited | Real estate | 1997 |
| DON 360 (PVT) Ltd | Manufacturing | 2024 |
| Donadel Cook Ltd | Hospitality | 2024 |