| East Anglian Haulage Limited | Manufacturing | 1991 |
| East Anglian Plumbing and Heating Centre Limited | Wholesale & retail | 1999 |
| East Flex Ltd | Transport & logistics | 2025 |
| East Global Int'L Group Limited | Extraterritorial | 2014 |
| East Malling Services Ltd. | Professional & scientific | 1989 |
| East of England Buildings Preservation Trust | Professional & scientific | 1984 |
| East of England Business Limited | Extraterritorial | 2016 |
| East Sea Trade Company Limited | Manufacturing | 2023 |
| East Wind Projects Ltd | Professional & scientific | 2014 |
| Easten Industry Co., Ltd | Extraterritorial | 2019 |
| Eastern Academic Health Science Network | Health & social care | 2013 |
| Eastern Builders Safety Group Limited | Construction | 1979 |
| Eastern Counties Construction Limited | | 1977 |
| Eastern Deer Ltd | Agriculture & fishing | 2025 |
| Eastern Electrics Ltd | Extraterritorial | 2022 |
| Eastern Game Ltd. | Agriculture & fishing | 2012 |
| Eastern Insight Limited | Professional & scientific | 2015 |
| Eastern Learning Alliance | Education | 2012 |
| Eastern Marquee Company Limited | Administrative & support | 2002 |
| Eastern Property Management Company Limited | Real estate | 1982 |
| Eastern Radiology Services Ltd | Health & social care | 2016 |
| Eastern Region Ministry Course | Education | 2001 |
| Eastgate Vintage Limited | Real estate | 2003 |
| Eastvigorous Industry Limited | Professional & scientific | 2014 |
| Eastward Traffic Equipment Limited | Wholesale & retail | 2021 |
| Eastwest Cultural Exchange Ltd | Education | 2010 |
| Eastwest Education Group Ltd | Education | 2011 |
| Eastwind Cambridge Limited | Wholesale & retail | 2001 |
| Eastwood Production Services Ltd | Construction | 2005 |
| Eastwood Property Services Ltd | Real estate | 2018 |
| Eastwood Records Limited | Information & communication | 2016 |
| Easy Digital Ltd | Wholesale & retail | 2007 |
| Easyback Service Ltd | Administrative & support | 2025 |
| Easyflow Logistics Limited | Financial services | 2024 |
| Easylift Scaffolding Ltd | Construction | 2019 |
| Easyrent Cambs Ltd | Real estate | 2025 |
| Easyride Express Ltd | Transport & logistics | 2025 |
| EAT Less Move More Limited | Other services | 2015 |
| Eatalians PVT Limited | Hospitality | 2024 |
| EATCAFE24 Ltd | Hospitality | 2023 |
| Eaton Capital Limited | Professional & scientific | 2022 |
| Ebby Care and Services Ltd | Hospitality | 2026 |
| Ebby G Trading Ltd | Wholesale & retail | 2025 |
| EBC Enterprises Limited | Financial services | 2018 |
| Ebenezer House Holdings Limited | Financial services | 2025 |
| EBP Services Ltd | Arts & recreation | 2024 |
| EC English Bristol Limited | Education | 2010 |
| EC English Cambridge Limited | Education | 1996 |
| EC English London Limited | Education | 1997 |
| EC English Manchester Limited | Education | 2012 |
| EC English Oxford Limited | Extraterritorial | 2012 |
| EC Recruitment Ltd | Administrative & support | 2023 |
| EC UK Investments Limited | Financial services | 2011 |
| Ecardpay Ltd | Wholesale & retail | 2023 |
| Eccleston Place (Cambridge) Management Company Limited | Households | 2015 |
| Eccleston Place Limited | Professional & scientific | 2023 |
| Ecdc Holdings Limited | Financial services | 2025 |
| Echo Care Alliance Ltd | Health & social care | 2024 |
| Echo Education Ltd | Education | 2022 |
| ECI Amsterdam UK Ltd | Professional & scientific | 2025 |
| Eck-Technology.Com Ltd | Information & communication | 2005 |
| Eclectic Recruitment Ltd | Administrative & support | 2018 |
| Eclipse (EA) Management Company Limited | Households | 2007 |
| Eclipse Planning Services Limited | Professional & scientific | 2011 |
| Eclipseproductmanufacturing Ltd | Manufacturing | 2024 |
| Ecloudy Limited | Extraterritorial | 2022 |
| ECM Selection (Holdings) Limited | Administrative & support | 2003 |
| ECM Selection Limited | Financial services | 2020 |
| Eco Centro Systems Ltd | Extraterritorial | 2022 |
| Eco Grant Renewables Ltd | Administrative & support | 2019 |
| Eco Marine Service Ltd | Wholesale & retail | 2023 |
| Eco-Inject Ltd | Professional & scientific | 2023 |
| Eco-Logical Building Ltd | Construction | 2026 |
| Eco-Logical Developments Ltd | Professional & scientific | 2023 |
| Eco-Sukgarden (UK) Company Limited | Extraterritorial | 2021 |
| Eco-Vibration UK Ltd | Manufacturing | 2022 |
| Eco.Wood International Trade Limited | Extraterritorial | 2025 |
| Ecochoice Limited | Wholesale & retail | 2005 |
| Ecolabnl Chemical Ltd | Manufacturing | 2025 |
| Ecology Link Ltd | Professional & scientific | 2009 |
| Ecomedge Solution Ltd | Manufacturing | 2024 |
| Ecomm Limited | Information & communication | 2012 |
| Ecomtrend Solutions Ltd | Manufacturing | 2024 |
| Ecopure Waters International Limited | Wholesale & retail | 2010 |
| Ecoroute Limited | Professional & scientific | 1997 |
| Ecoscentric Limited | Information & communication | 2002 |
| Ecosphere Strategies Limited | Professional & scientific | 2024 |
| Ecotransform Ltd | Professional & scientific | 2026 |
| Ecountz Limited | Administrative & support | 2013 |
| ECT Nation Ltd | Other services | 2020 |
| ECV Utilities Limited | Professional & scientific | 2016 |
| ED Project Consulting Limited | Professional & scientific | 2014 |
| Edamon Limited | Hospitality | 2003 |
| EDC Holdings Group Limited | Mining & quarrying | 2020 |
| Eddies (Cambridge) Ltd | Hospitality | 2026 |
| Eddies Cafe Limited | Hospitality | 2025 |
| Eddies Engineering & Solutions UK Ltd | Professional & scientific | 2022 |
| Eddington Data Ltd | Information & communication | 2025 |
| Eddison Consulting LLP | | 2024 |
| Eden Grey Creative Ltd | Manufacturing | 2024 |