| Eden Property Investment and Management Ltd | Construction | 2021 |
| Eden Raintree Ltd | Health & social care | 2023 |
| Eden's Gardeners Limited | Administrative & support | 2023 |
| Edens Flowers Limited | Wholesale & retail | 2009 |
| Edenseven Limited | Professional & scientific | 2020 |
| Edeva Court (Cambridge) Freehold Limited | Households | 2022 |
| Edeva Court (Cambridge) RTM Company Limited | Households | 2020 |
| Edge Woodbury Limited | Professional & scientific | 2012 |
| Edgeetech Ltd | Information & communication | 2019 |
| Edgefolio UK Limited | Information & communication | 2015 |
| EDH Aviation Ltd | Transport & logistics | 2022 |
| Ediebert Limited | Wholesale & retail | 2023 |
| Edinbridge Limited | Professional & scientific | 2022 |
| Edison Innovation Services Limited | Professional & scientific | 2026 |
| Edmp Techav Ltd | Manufacturing | 2025 |
| Edmund Bibby Ltd | Manufacturing | 2024 |
| Edmund Burke Foundation | Professional & scientific | 2023 |
| Edron Engineering Services Limited | Manufacturing | 2004 |
| Edspire Labs Limited | Education | 2025 |
| EDU - Catering (UK) Ltd | Administrative & support | 2003 |
| Eduards Daleckis Paint Ltd | Manufacturing | 2022 |
| Eduavor Ltd | Education | 2025 |
| Educatalyst Limited | Education | 2025 |
| Educaterers Limited | Hospitality | 2017 |
| Education and Community Engagement Consultancy Ltd | Education | 2026 |
| Education for Business Managers and Administrators Ltd | Education | 2010 |
| Education Gateway UK Limited | Education | 2009 |
| Education Services 2010 | Education | 2011 |
| Educational Futures Ltd | Education | 2025 |
| Educational Psychology Ltd | Health & social care | 2025 |
| Edusafari Publishing Ltd | Wholesale & retail | 2025 |
| EDW Aero Maintenance Ltd | Manufacturing | 2026 |
| Edward Cheese Book Conservation Limited | Manufacturing | 2025 |
| Edward Smart Limited | Administrative & support | 2007 |
| Edward VII Estate Residents Management Company Limited | Households | 2014 |
| EDX Medical Group PLC | Financial services | 2021 |
| EDX Medical Ltd | Professional & scientific | 2022 |
| EEO Grill Ltd | Hospitality | 2023 |
| EF EF Ltd | Manufacturing | 2024 |
| Efelija Ltd | Wholesale & retail | 2021 |
| Efes Cambridge Limited | Hospitality | 2025 |
| Effervescence Therapeutics Ltd | Professional & scientific | 2024 |
| Effortless Group Ltd | Wholesale & retail | 2019 |
| Effy Studios Ltd | Arts & recreation | 2025 |
| Efirsty Enterprise Co., Ltd. | Extraterritorial | 2014 |
| EFS Manufacturing Limited | Administrative & support | 2006 |
| EG Technology Limited | Professional & scientific | 2002 |
| Egan Medical Limited | Health & social care | 2015 |
| Egerton Place Management Limited | Households | 2018 |
| Egerton Place NO. 2 Management Limited | Households | 2018 |
| Egerton Place NO. 3 Management Limited | Households | 2020 |
| EGG and Spoon Holdings Limited | Arts & recreation | 2018 |
| Egghead & Boffin Ltd | Information & communication | 2015 |
| Eghead Limited | Professional & scientific | 2012 |
| Egis Associates Limited | Professional & scientific | 1995 |
| Egls Transport Ltd | Transport & logistics | 2025 |
| EGP Property Limited | Real estate | 2011 |
| EGT Group Limited | Financial services | 2019 |
| EGT Trustees Limited | Professional & scientific | 2023 |
| EH Real Estate Investments Ltd | Real estate | 2022 |
| Eidetika Limited | Information & communication | 2004 |
| EIG International Limited | Financial services | 2009 |
| EIGHT19 Limited | Extraterritorial | 2010 |
| Eightfivetwo Consulting Ltd | Other services | 2020 |
| EIK Ltd | Health & social care | 2014 |
| Eikon Architects Limited | Professional & scientific | 2016 |
| Einstein Limited | Professional & scientific | 2020 |
| Eisao Trading Co., Ltd | Wholesale & retail | 2024 |
| Eisneramper Global Limited | Professional & scientific | 2014 |
| Eitmaster Limited | Manufacturing | 2022 |
| Eivx Publishing Group Limited | Information & communication | 2024 |
| EJ Bars Ltd | Hospitality | 2023 |
| EJ Holdings Limited | Financial services | 2023 |
| EJ Software Ltd | Information & communication | 2020 |
| Ejhservices Ltd | Wholesale & retail | 2025 |
| EJL Inspection Services Ltd | Manufacturing | 2016 |
| EJW Solutions Limited | Education | 2013 |
| Ekeller Limited | Information & communication | 2022 |
| Ekioh Ltd | Information & communication | 2006 |
| Eklektek Ltd | Manufacturing | 1996 |
| Ekmt Ltd | Health & social care | 2024 |
| EKO Kitchen Limited | Hospitality | 2014 |
| EKO Wisbech Limited | Real estate | 2010 |
| Ekostate Ltd | Real estate | 2022 |
| EKS Aviation Limited | Manufacturing | 2023 |
| Eksell Ltd | Professional & scientific | 2016 |
| EL Pinar Services Ltd | Manufacturing | 2023 |
| EL RIO Media Ltd | Information & communication | 2014 |
| ELA & Mete Ltd | Real estate | 2024 |
| ELA Active Limited | Arts & recreation | 2012 |
| Ela&Aviation Ltd | Manufacturing | 2024 |
| Elaj'E Limited | Other services | 2007 |
| Elanga IP Ltd | Administrative & support | 2026 |
| Elantratech Ltd | Professional & scientific | 2023 |
| Elavet Ltd | Manufacturing | 2026 |
| Elazin Engineering Ltd | Manufacturing | 2026 |
| Elderwood (Crowland) Management Company Limited | Households | 2024 |
| Eldon Group Limited | Financial services | 2024 |
| Eldon Promenade Limited | Financial services | 2024 |
| Eldon Tredegar Limited | Construction | 2014 |