| Decades Healthcare Services Ltd | Public administration | 2026 |
| Decades Properties Ltd | Real estate | 2021 |
| Dedicated Solutions Limited | Manufacturing | 2019 |
| Deere Photographic Ltd | Professional & scientific | 2024 |
| Defiant Technology Ltd | Extraterritorial | 2023 |
| Define Studio Limited | Other services | 2024 |
| DEL Satellite Ltd | Education | 2024 |
| Delhi 13 Limited | Hospitality | 2024 |
| Delhiontrent Limited | Hospitality | 2025 |
| Delicate Hospitality Services Ltd | Manufacturing | 2023 |
| Delicious Valley Ltd | Hospitality | 2026 |
| Delirush Foods Ltd | Hospitality | 2024 |
| Dellner Polymer Solutions Limited | Manufacturing | 1997 |
| Dellner Woodville Limited | Financial services | 2008 |
| Delstron Systems Limited | Manufacturing | 1991 |
| Delta Meridian Group Ltd | Construction | 2026 |
| Dementia Care at Home Ltd | Health & social care | 2025 |
| Denis INT Ltd | Transport & logistics | 2024 |
| Dental Education Lead Limited | Education | 2022 |
| Dents Auto Electrical Limited | Real estate | 1960 |
| Deranged Squirrel Enterprises Ltd | Real estate | 2020 |
| Deranged Squirrel Group Ltd | Information & communication | 2019 |
| Derby Building Developments Limited | Construction | 2024 |
| Derby Detailing & Repair Ltd | Wholesale & retail | 2024 |
| Derby Family Chiropractic Ltd | Health & social care | 2015 |
| Derby Gastech Limited | Wholesale & retail | 2012 |
| Derby Health Staffing Ltd | Administrative & support | 2018 |
| Derby Laminates Limited | Manufacturing | 2007 |
| Derby Skip Hire Ltd | Extraterritorial | 2015 |
| Derby Traders Ltd | Wholesale & retail | 2025 |
| Derby Turn Ltd | Wholesale & retail | 2022 |
| Derby Windows Ltd | Construction | 2025 |
| Derbyshire Classic Cars Limited | Wholesale & retail | 2017 |
| Derventio Venetian Creations Ltd | Construction | 2024 |
| Derwent Aviation Consulting Ltd | Professional & scientific | 2010 |
| Derwent Technologies Limited | Financial services | 2017 |
| DET Services Ltd | Hospitality | 2026 |
| Deus EX Machina Maritime Limited | Wholesale & retail | 2022 |
| Developments by R&N Ltd | Manufacturing | 2019 |
| Devoli Ltd | Health & social care | 2025 |
| Devram Joinery Ltd | Manufacturing | 2021 |
| Dewsbury Group Ltd | Financial services | 2026 |
| Dexterisys Consulting Limited | Professional & scientific | 2008 |
| DGS Commercials Limited | Transport & logistics | 2025 |
| Dhawar Ltd | Information & communication | 2019 |
| DIA & Miru Health Ltd | Wholesale & retail | 2022 |
| DIA Transport Ltd | Transport & logistics | 2019 |
| Dial Direct UK Ltd | Information & communication | 2004 |
| Diamond Bright Group Ltd | Construction | 2019 |
| Diamond Bright Projects Ltd | Real estate | 2020 |
| Diamonds N Pearls Pet Services Limited | Professional & scientific | 2018 |
| Diclasse&Co Limited | Information & communication | 2025 |
| Diesel Code Ltd | Administrative & support | 2025 |
| Digital Freedom Path Ltd | Professional & scientific | 2025 |
| Dilbe Ltd | Real estate | 2023 |
| Dimov 22 Ltd | Wholesale & retail | 2022 |
| Dimov 24 Ltd | Transport & logistics | 2024 |
| Dinamead Limited | Real estate | 1989 |
| Dine Dynamics Limited | Hospitality | 2025 |
| Dino Chef Limited | Hospitality | 2024 |
| Direct Marque Limited | Professional & scientific | 2012 |
| Direct Motor Assessors Limited | Wholesale & retail | 2008 |
| Direct Plumbing & Heating Solutions Ltd | Construction | 2018 |
| Dirty Roots Limited | Wholesale & retail | 2025 |
| Diverse Talent Solutions Ltd | Administrative & support | 2019 |
| DJC Media Solutions Ltd | Professional & scientific | 2025 |
| Djocar Ltd | Extraterritorial | 2023 |
| DJW Music Ltd | Arts & recreation | 2012 |
| Dkab Consulting Ltd | Information & communication | 2023 |
| Dkab Property Limited | Real estate | 2024 |
| DKB Electrical Limited | Construction | 2025 |
| Dkmx Ltd | Transport & logistics | 2017 |
| DKP Transport Ltd | Transport & logistics | 2021 |
| Dkpharm Ltd | Professional & scientific | 2021 |
| DLW Home Improvement Specialists Ltd | Construction | 2025 |
| DM Accounting and Payroll Ltd | Wholesale & retail | 2016 |
| DM Timber Framing Limited | Construction | 2018 |
| DM27 Engineering Limited | Hospitality | 2021 |
| DMD Floor Screeds Limited | Construction | 2018 |
| Dmitrijs Group Ltd | Manufacturing | 2019 |
| Dmjb Developers Limited | Information & communication | 2018 |
| DMW Hygiene Limited | Health & social care | 2014 |
| Dmwsl 631 Limited | Financial services | 2010 |
| Dmwsl 632 Limited | Financial services | 2010 |
| Dmwsl 633 Limited | Financial services | 2010 |
| DN Spray Maintenance Ltd | Construction | 2024 |
| DNO Properties Ltd | Real estate | 2025 |
| DNT Construction Ltd | Construction | 2015 |
| Doaa Ltd | Extraterritorial | 2011 |
| Doaacare Ltd | Health & social care | 2017 |
| Dodo Ltd | Construction | 2025 |
| Dog Knows Ltd | Administrative & support | 2011 |
| Doggy Day Care Burton Ltd | Other services | 2020 |
| Doggy Heaven Ltd | Wholesale & retail | 2021 |
| Dollhouse Bakery Limited | Hospitality | 2014 |
| Dolls Lounge Aesthetic & Beauty Ltd | Other services | 2024 |
| Dolmans Fire Safety Ltd | Public administration | 2025 |
| Dominas DW Ltd | Transport & logistics | 2018 |
| Donner Trio Ltd | Hospitality | 2026 |
| Donutz Music Ltd | Wholesale & retail | 2024 |