| Door & Joinery Solutions Limited | Wholesale & retail | 2003 |
| Double R Spirits Ltd | Manufacturing | 2023 |
| Dovasy Transport Ltd | Transport & logistics | 2025 |
| Dovehouse (Redditch) Ltd | Health & social care | 2024 |
| DPFMAN24 Limited | Manufacturing | 2021 |
| DPS Training & Consultancy Limited | Education | 2013 |
| DPT ENG Limited | Transport & logistics | 2024 |
| DPX Golf Ltd | Arts & recreation | 2026 |
| DR RA Aesthetics Ltd | Health & social care | 2025 |
| DR Riasat Hussain Ltd | Health & social care | 2019 |
| DR. Calapaci Aesthetics Ltd | Health & social care | 2025 |
| DR. Conversions Ltd | Other services | 2024 |
| Draycott Cliff Limited | Construction | 2005 |
| Dream Competitions Ltd | Information & communication | 2025 |
| Dreamcatcher Gifts Limited | Wholesale & retail | 2022 |
| Dreams 4 Life Ltd | Real estate | 2025 |
| Dreich Film Ltd | Information & communication | 2023 |
| Drillco Ltd | Construction | 2015 |
| Driscolls (Insulation Services) Holdings Limited | Financial services | 2017 |
| Driscolls (Insulation Services) Limited | Construction | 2000 |
| Driscolls Thermal Solutions Limited | Construction | 2013 |
| Drive Away Car Sales & Motors Ltd | Wholesale & retail | 2025 |
| Drive by G Ltd | Transport & logistics | 2025 |
| Drive Change for Good Limited | Extraterritorial | 2023 |
| Drive Time Vocational Solutions Limited | Education | 2015 |
| DRIVEN2ACHIEVE Ltd | Professional & scientific | 2020 |
| Driver GP Ltd | Transport & logistics | 2018 |
| Driver TOM Limited | Transport & logistics | 2022 |
| Drivers and Medicals Limited | Health & social care | 2017 |
| Drivetime-Vts Limited | Education | 2014 |
| DRS Services Ltd | Professional & scientific | 2025 |
| Drsofa Ltd | Wholesale & retail | 2023 |
| DSE Assessments Limited | Other services | 2009 |
| Dsjoneselectrical Limited | Construction | 2020 |
| DSW Planning Services Ltd | Professional & scientific | 2013 |
| DT Online Ltd | Education | 2024 |
| DTH Services Limited | Wholesale & retail | 2015 |
| Dual Logistic Ltd | Transport & logistics | 2013 |
| Dual Maintenance Ltd | Wholesale & retail | 2023 |
| Dualcent Ltd | Wholesale & retail | 2025 |
| Duc-Kit Pro Ltd | Wholesale & retail | 2017 |
| Duckworth Planning and Design Ltd | Professional & scientific | 2014 |
| Dudley’S Canine Retreat Ltd | Other services | 2026 |
| Dugort Ltd | Real estate | 2022 |
| Dulux Products Ltd | Wholesale & retail | 2020 |
| Dunbar Pubs Ltd | Hospitality | 2023 |
| Duncan Redpath Limited | Information & communication | 2010 |
| Dune Homes Ltd | Real estate | 2025 |
| Dunstall Contracts Limited | Construction | 2008 |
| Dunstall Homes Limited | Construction | 2002 |
| Dunvis Consulting Ltd | Professional & scientific | 2025 |
| DUO Nails Ltd | Other services | 2018 |
| Durham Products Limited | Wholesale & retail | 2007 |
| Duslasst (BOT) Limited | Manufacturing | 2010 |
| Duvestone Limited | Financial services | 2025 |
| DV Builder Ltd | Construction | 2019 |
| DVM Enterprises Limited | Wholesale & retail | 2004 |
| DW Electrical Contracting Ltd | Construction | 2024 |
| Dwcm Ltd | Education | 2023 |
| Dwits Services Ltd | Real estate | 2017 |
| DY Ferguson and SON Properties and Investments Limited | Real estate | 2025 |
| Dynamic Air Conditioning Limited | Construction | 1999 |
| Dynamic Service Solutions Ltd | Other services | 2020 |
| Dynamics Training Limited | Information & communication | 2011 |
| E & a UK Properties Limited | Real estate | 2020 |
| E-Instruments Limited | Administrative & support | 2020 |
| E.C.S.Properties Limited | Real estate | 1964 |
| E.D. Bathroom Installations Ltd | Construction | 2009 |
| E.Gouldthorp Properties Ltd | Real estate | 2025 |
| E2 Developments Ltd | Real estate | 2010 |
| Eagle Connect Ltd | Construction | 2018 |
| Eames Healthtech Ltd | Wholesale & retail | 2026 |
| EAR Muse Ltd | Health & social care | 2025 |
| EAR Sanctuary Ltd | Health & social care | 2023 |
| EAR WAX Clinic Burton & Derby Ltd | Health & social care | 2025 |
| Earthing Risk Management Limited | Information & communication | 2002 |
| Easons Associates Limited | Professional & scientific | 2024 |
| East Midland Developments Limited | Construction | 2024 |
| Eastern Seahorse Limited | Hospitality | 2021 |
| Eastgate Business Centre Ltd | Households | 2008 |
| Easy Dealz Ltd | Wholesale & retail | 2025 |
| Easy Gate Transport Solution Ltd | Wholesale & retail | 2023 |
| Easy Photography Ltd | Professional & scientific | 2023 |
| Ebrain Solutions Ltd | Wholesale & retail | 2017 |
| EBY Transport Ltd | Transport & logistics | 2024 |
| Echo Fest Limited | Arts & recreation | 2026 |
| Eco Energy Plus Ltd | Construction | 2023 |
| Eco Energy Works Limited | Wholesale & retail | 2017 |
| Eco Safe Driver Limited | Transport & logistics | 2018 |
| Ecocert Renewables Ltd | Construction | 2018 |
| Ecomar Navigestion Ltd | Transport & logistics | 2016 |
| ECS UK Group Ltd. | Construction | 2012 |
| ECS UK Holdings Limited | Construction | 2023 |
| Eden Garden Trading Limited | Wholesale & retail | 2006 |
| Edens Cocoon Limited | Professional & scientific | 2025 |
| Edge Pubs Ltd | Hospitality | 2025 |
| Edgewyn Properties Ltd | Real estate | 2025 |
| Edinburgh Healthcare Ltd | Health & social care | 2023 |
| Ednaston Investments Limited | Real estate | 1990 |
| EDR Construct Ltd | Construction | 2019 |