| Crrl Ltd | Construction | 2024 |
| Crump Investments Ltd | Real estate | 2020 |
| Crvn Haulage Ltd | Transport & logistics | 2026 |
| Crystal EAR Care Ltd | Other services | 2023 |
| CS Bookkeeping Services Limited | Professional & scientific | 2008 |
| CS Fleet Audit Ltd | Transport & logistics | 2020 |
| CS RAD Ltd | Professional & scientific | 2019 |
| CSH Holdings Limited | Financial services | 2001 |
| CT Rentals Ltd | Real estate | 2020 |
| Cube Associates (UK) Ltd | Professional & scientific | 2008 |
| Cup-Pro Limited | Manufacturing | 2018 |
| Cura Collective Limited | Education | 2025 |
| Curae Healthcare Limited | Health & social care | 2020 |
| CURV360 Limited | Manufacturing | 2015 |
| Curvium Group Limited | Information & communication | 2023 |
| Curzon Woods Limited | Information & communication | 2012 |
| CUT & DRY Ltd | Other services | 2012 |
| Cutlers Sales and Hire Limited | Wholesale & retail | 2015 |
| Cutprintengrave Ltd | Manufacturing | 2025 |
| Cvoluk Ltd | Wholesale & retail | 2025 |
| Cwae Holdings Limited | Real estate | 2019 |
| CWB Engineering Ltd | Construction | 2016 |
| Cyber Security Valley UK Limited | Information & communication | 2020 |
| Cybersaver Mart Ltd | Wholesale & retail | 2024 |
| Cybunkr Ltd | Information & communication | 2022 |
| Cyco Doctor Limited | Wholesale & retail | 2013 |
| Cytra Holding Limited | Financial services | 2017 |
| Czacha 1981 Ltd | Transport & logistics | 2021 |
| D & BE Ltd | Other services | 2018 |
| D & D Glass Limited | Construction | 1995 |
| D & K Doman Limited | Administrative & support | 2016 |
| D B S Chemicals Limited | Professional & scientific | 1993 |
| D C I Heating Services Limited | Construction | 2007 |
| D Cooper Construction Limited | Construction | 1997 |
| D Cooper Properties Limited | Real estate | 2015 |
| D H Tech Ltd | Wholesale & retail | 2025 |
| D K S (Burton) Limited | Construction | 2003 |
| D Mcadam Building Services Ltd | Construction | 2012 |
| D Pearson Properties Ltd | Real estate | 2023 |
| D-Hive Limited | Transport & logistics | 2009 |
| D-Stress Consultancy Limited | Information & communication | 2005 |
| D-Velop Ltd | Information & communication | 2024 |
| D. Alexander & Co. Limited | Professional & scientific | 2004 |
| D.P. Improvements Ltd | Construction | 2008 |
| D.S.E Accountancy Limited | Professional & scientific | 2020 |
| D.Swinfield Limited | Real estate | 2023 |
| D3 Content Creation Limited | Information & communication | 2023 |
| Da-Jeans Ltd | Wholesale & retail | 2023 |
| Daffodil House (Coalville) Ltd | Health & social care | 2024 |
| Dagda Services Ltd | Professional & scientific | 2024 |
| Dagoult Limited | Wholesale & retail | 2023 |
| DAI452 Limited | Financial services | 2018 |
| Daida Developments Ltd | Construction | 2023 |
| Daida Holdings Ltd | Real estate | 2015 |
| Daily Orbit Hub Ltd | Wholesale & retail | 2026 |
| Dairy Nation Limited | Wholesale & retail | 2013 |
| Daisy Brook Kennels Limited | Other services | 2013 |
| Daisy House (Burton on Trent) Ltd | Health & social care | 2021 |
| Dalebrook Accountants Ltd | Professional & scientific | 2025 |
| Dalgety Farm Systems Limited | Manufacturing | 2016 |
| Dallow Street MOT Ltd | Wholesale & retail | 2024 |
| Dams Security Ltd | Administrative & support | 2025 |
| DAN Potts ENG Ltd | Professional & scientific | 2024 |
| Dancer Home Improvement Supplies Ltd | Construction | 2021 |
| Danchip Healthcare Ltd | Health & social care | 2014 |
| Danielle Sarah Hair Ltd | Other services | 2019 |
| Daniz Ltd | Transport & logistics | 2015 |
| Danny Ocean Property Ltd | Real estate | 2025 |
| Dansey Group Ltd | Financial services | 2021 |
| Dansey Homes Ltd | Real estate | 2017 |
| Dantech Property Limited | Real estate | 2025 |
| Darban Ltd | Hospitality | 2018 |
| Darco Northern Major Limited | Administrative & support | 2020 |
| Darius Transit Limited | Transport & logistics | 2022 |
| Darkomat Ltd | Transport & logistics | 2021 |
| Darley Trade Holdings Limited | Financial services | 2023 |
| Darverse Ltd | Financial services | 2026 |
| Darwi Limited | Transport & logistics | 2016 |
| Darwin Mechanical Limited | Manufacturing | 2011 |
| Data Cycle Limited | Professional & scientific | 2016 |
| Data Protection Professional Services Ltd | Professional & scientific | 2026 |
| Datties Soul Food Academy Ltd | Hospitality | 2021 |
| Dauntless Travellers Ltd | Hospitality | 2024 |
| David Brown Remastered Ltd | Manufacturing | 2026 |
| David G Barton Limited | Professional & scientific | 2004 |
| David Raybould & Associates Limited | Professional & scientific | 2006 |
| David Simpson Heating & Plumbing Engineers Limited | Construction | 2003 |
| Davies Plastering (Leicester) Limited | Construction | 2005 |
| Dawnwind Properties Limited | Professional & scientific | 2006 |
| Dayaprojects Ltd | Real estate | 2025 |
| DB Electrical & Renewables Ltd | Construction | 2024 |
| Dbrothersuk Ltd | Transport & logistics | 2025 |
| DC Joinery (Midlands) Limited | Construction | 2016 |
| DC Power and Data Ltd | Administrative & support | 2016 |
| DDH Logistics Ltd | Transport & logistics | 2025 |
| DE14 Fastfood Ltd | Hospitality | 2026 |
| Dead Weight Limited | Manufacturing | 2026 |
| Deancomm Limited | Construction | 2019 |
| Dear (Holdings) Limited | Financial services | 2013 |
| Deb's Kitchen Cakes Limited | Wholesale & retail | 2014 |