| Dongbeifeng Limited | Hospitality | 2024 |
| Donkey Consulting Ltd | Professional & scientific | 2025 |
| Donovan Tax and Accountancy Ltd | Professional & scientific | 2023 |
| Dons Construction Limited | Construction | 2019 |
| Dora D Design Ltd | Wholesale & retail | 2022 |
| Doralis Ltd | Wholesale & retail | 2025 |
| Double Crown Industries Limited | Real estate | 2023 |
| Downton Tech Limited | Information & communication | 2025 |
| Doyouknowa Limited | Professional & scientific | 2025 |
| DPC Contracts Ltd | Construction | 2012 |
| DPN Transport Ltd | Transport & logistics | 2023 |
| DPS Distribution Limited | Wholesale & retail | 2004 |
| DR Calm Ltd | Wholesale & retail | 2020 |
| DR Dent Ltd | Wholesale & retail | 2009 |
| DR Rani Ltd | Wholesale & retail | 2016 |
| DR Seth Cancer Wellness Ltd | Health & social care | 2023 |
| DR. Matcha Studio Ltd | Professional & scientific | 2025 |
| Dragon Defog Ltd | Administrative & support | 2025 |
| Draughting & Computer Services Ltd | Information & communication | 1997 |
| Drayton Boiler Services Limited | Construction | 2002 |
| DRH Care Ltd | Health & social care | 2024 |
| Drink Tranquilo Ltd | Manufacturing | 2024 |
| Drjc Property Limited | Real estate | 2025 |
| Drury Electrical Ltd | Manufacturing | 2016 |
| DRY Wall Surveying Services Limited | Construction | 2008 |
| Dryfit Ltd | Construction | 2017 |
| DS Jointing Solutions Ltd | Construction | 2020 |
| DS Prime Ltd | Construction | 2024 |
| DSH Flooring Limited | Construction | 2012 |
| DT Design Studio Limited | Professional & scientific | 2023 |
| DTG Limited | Extraterritorial | 2004 |
| DUB4 Limited | Construction | 2025 |
| Duck & Deer Limited | Construction | 2024 |
| Dudman Enterprises Limited | Professional & scientific | 2022 |
| Dunamis Coaching Limited | Health & social care | 2022 |
| Dunbeath Pecunia Limited | Financial services | 2020 |
| Duncan Yeardley Estate Agent Limited | Real estate | 2010 |
| Dune-Cec Limited | Professional & scientific | 2024 |
| Duze Solutions Ltd | Administrative & support | 2013 |
| DVR SRV Ltd | Transport & logistics | 2025 |
| DW Fitness 4 Sport Ltd | Arts & recreation | 2025 |
| DW Search Limited | Administrative & support | 2017 |
| Dwarfsun Multimedia Services Ltd. | Information & communication | 2014 |
| Dyad Connect Ltd | Professional & scientific | 2022 |
| Dyanamix Ltd | Information & communication | 2009 |
| Dycard Developments Ltd | Construction | 2017 |
| Dynamic Energy Consultants Limited | Professional & scientific | 2022 |
| Dynamic Media Solutions Limited | Administrative & support | 2009 |
| Dynamic Security & Fire Ltd | Administrative & support | 2013 |
| Dyncrop UK Ltd | Wholesale & retail | 2022 |
| Dziva Care Ltd | Health & social care | 2013 |
| E LEE Parks Limited | Real estate | 2018 |
| E&F IT Consultants Ltd | Information & communication | 2024 |
| E&H Landscapers Limited | Professional & scientific | 2022 |
| E&H Property Maintenance Limited | Professional & scientific | 2025 |
| E&S Solutions Ltd | Information & communication | 2013 |
| E.A. Homes Ltd | Construction | 2015 |
| E2E BTC Limited | Professional & scientific | 2009 |
| E4DATA Ltd | Information & communication | 2012 |
| Eagle and Rose Properties Limited | Real estate | 2026 |
| Eagle Film and TV Ltd | Information & communication | 2023 |
| Earls Healthcare Ltd | Health & social care | 2021 |
| East View Court Management Company Limited | Households | 1990 |
| Eastern Energy Development Ltd | Professional & scientific | 2018 |
| Eastern Vegan 242 Ltd | Hospitality | 2024 |
| Eastwood Collective Ltd | Education | 2025 |
| Easy Animal Studio Ltd | Information & communication | 2020 |
| Easypay Limited | Professional & scientific | 1979 |
| Eazy Haul Logistics Ltd | Transport & logistics | 2026 |
| Ebaid Co. Ltd., | Hospitality | 1998 |
| EBL Property Group Limited | Real estate | 2023 |
| EC Automotive Limited | Wholesale & retail | 2026 |
| EC1A Limited | Construction | 2016 |
| ECF Group (Holdings) Ltd | Financial services | 2025 |
| Echoplex Films Limited | Arts & recreation | 2019 |
| Eco Clean Facilities Ltd | Administrative & support | 2025 |
| Eco Renewables Ltd | Construction | 2016 |
| Ecoeus Limited | Administrative & support | 2019 |
| Ecolec Installations Limited | Construction | 2012 |
| Ecological Rewards Ltd | Information & communication | 2019 |
| Ecom Analytica Limited | Information & communication | 2023 |
| Ecomix Concrete and Aggregates Limited | Manufacturing | 2019 |
| Ecoplay&Ecolearn Limited | Wholesale & retail | 2025 |
| Ecotech Pest Control Ltd | Administrative & support | 2021 |
| Ecx.Io Ltd | Professional & scientific | 2009 |
| Eden Barbers Limited | Other services | 2016 |
| Eden Cottages Morecambe Ltd | Hospitality | 2023 |
| Eden Energy Ltd | Construction | 2025 |
| Edenfold Ltd | Professional & scientific | 2025 |
| Edens Garden Services Limited | Administrative & support | 2022 |
| Edgbarrow Trampoline Club | Arts & recreation | 2022 |
| Edge Case Technical Ltd | Information & communication | 2016 |
| Education Boutique Ltd | Education | 2016 |
| Edveoc Consultancy Limited | Education | 2022 |
| Edymedix & Courier Ltd | Transport & logistics | 2018 |
| Eecommerce Solutions Ltd | Wholesale & retail | 2023 |
| EEE London Ltd | Construction | 2025 |
| EFC Trading Ltd | Wholesale & retail | 2018 |
| Effect Electrical Ltd | Construction | 2019 |
| Effervescent Events Ltd | Administrative & support | 2022 |