| Effusive Technologies Ltd | Information & communication | 2010 |
| EGH Housing Managment Ltd | Real estate | 2024 |
| Egnatia Retail Ltd | Wholesale & retail | 2019 |
| EHO Crafted Interiors Ltd | Construction | 2018 |
| Eight Five Marketing Limited | Professional & scientific | 2020 |
| Eighteen 79 Ltd | Information & communication | 2016 |
| EJF Search and Selection Limited | Administrative & support | 2010 |
| Ekantik Physiotherapy Ltd | Health & social care | 2026 |
| Ekistics Capital Advisors LLP | | 2005 |
| Ekom Superstore Limited | Wholesale & retail | 2011 |
| EL Marsh Care Home Ltd | Health & social care | 2012 |
| Electra Networks Limited | Information & communication | 2012 |
| Electrone Ltd | Information & communication | 2015 |
| Element and Grain Ltd | Manufacturing | 2025 |
| Elements Henley Ltd | Other services | 2014 |
| Elevatex Solutions Ltd | Professional & scientific | 2024 |
| Elgon Support Ltd | Transport & logistics | 2023 |
| Eliminator Sports Limited | Information & communication | 2025 |
| Elite Flooring Specialists Limited | Construction | 2024 |
| Elite Maintenance 03 Ltd | Administrative & support | 2024 |
| ELITE4 Technologies Ltd | Information & communication | 2024 |
| Eliteflow Services Limited | Construction | 2021 |
| Ellie's Beauty (Warfield) Limited | Other services | 2023 |
| Ellie's Beauty Consultancy Limited | Other services | 2024 |
| Elliott Coaching Limited | Other services | 2024 |
| Ellis Auto & Electrical Ltd | Wholesale & retail | 2022 |
| Ellis Strategic Solutions Ltd | Professional & scientific | 2026 |
| Elster GAS Holdings Limited | Professional & scientific | 2013 |
| Elster Metering Holdings Limited | Professional & scientific | 1907 |
| Elster Metering Limited | Manufacturing | 1966 |
| Elster Solutions Limited | Professional & scientific | 2013 |
| Elster Water Metering Holdings Limited | Professional & scientific | 2005 |
| Elster Water Metering Limited | Manufacturing | 2013 |
| ELT Productions Ltd | Arts & recreation | 2026 |
| Elvasons Care Solutions Ltd | Professional & scientific | 2018 |
| Elysium Exosuit Ltd | Manufacturing | 2025 |
| Elysium Group Global Ltd | Financial services | 2021 |
| Elysium Logistics Ltd | Transport & logistics | 2021 |
| Elysium Luxury Investments Ltd | Other services | 2021 |
| Elysium Residences Ltd | Real estate | 2024 |
| Elysium Talent Management Ltd | Arts & recreation | 2020 |
| Emilie Lane SMP & PMU Ltd | Other services | 2025 |
| Emma Young Consulting Ltd | Professional & scientific | 2013 |
| Emmbedded Limited | Professional & scientific | 2026 |
| Emmett & Churchman Ltd | Professional & scientific | 2016 |
| Emmypresca Services Limited | Health & social care | 2023 |
| Empathra Counselling Ltd | Health & social care | 2026 |
| Emporia Trading Limited | Wholesale & retail | 2021 |
| Empyrean Construction Limited | Construction | 2010 |
| Enable Care & Support Limited | Health & social care | 2019 |
| Enable Electrical Ltd | Construction | 2024 |
| Enborne Corporate Ltd | Financial services | 2026 |
| Endquote Limited | Wholesale & retail | 2024 |
| Energy Efficient Solutions Group Ltd | Wholesale & retail | 2022 |
| Energy Saving Lighting Limited | Wholesale & retail | 2017 |
| Energy Saving Products Ltd | Wholesale & retail | 2008 |
| Enfinitie Limited | Information & communication | 2020 |
| Engage Convert Limited | Professional & scientific | 2016 |
| Engdanskot Ltd | Information & communication | 2015 |
| Engenius Group Limited | Professional & scientific | 2017 |
| Englemere Limited | Other services | 1987 |
| Englow Education Ltd | Education | 2022 |
| Enhanced Electrical Systems Ltd | Construction | 2018 |
| Enigmatec Ltd | Manufacturing | 2025 |
| Eniola Contract Limited | Information & communication | 2014 |
| Enri Grips Ltd | Professional & scientific | 2023 |
| Enrich Solutions Limited | Information & communication | 2010 |
| Ensco 1523 Limited | Wholesale & retail | 1999 |
| Enterprise Accountants Limited | Professional & scientific | 2003 |
| Enterprise Court Management Company Limited | Professional & scientific | 1992 |
| Entice Facility Management Ltd | Administrative & support | 2023 |
| Envelor Communications UK Ltd | Information & communication | 2008 |
| EP Sparky Ltd | Construction | 2019 |
| Epara Services UK Limited | Professional & scientific | 2015 |
| EPC Network Limited | Information & communication | 2012 |
| Epfop Ltd | Construction | 2015 |
| Epicor Software (UK) Limited | Information & communication | 1989 |
| EPK Transport & Logistics Ltd. | Transport & logistics | 2024 |
| EQU Alpha Limited | Information & communication | 2026 |
| Equestrienne Ltd | Administrative & support | 2011 |
| ER Events Ltd | Other services | 2024 |
| Erpion Ltd | Information & communication | 2022 |
| ERW Comms Limited | Information & communication | 2022 |
| Escaliers Limited | Construction | 1984 |
| Escapade Health Ltd. | Health & social care | 2019 |
| Esha Private Ltd | Real estate | 2024 |
| ESL Holdings Limited | Financial services | 2021 |
| Esme Roofing Limited | Construction | 2025 |
| Esoteric Research Group Ltd. | Professional & scientific | 2020 |
| Esperanza Dressage Limited | Other services | 2015 |
| Essential Gifts Hub Limited | Wholesale & retail | 2022 |
| Esskay North Limited | Real estate | 2020 |
| Esskay Vahpra Limited | Real estate | 2024 |
| Esspjay Limited | Real estate | 2023 |
| Eteach Education Advisers Limited | Administrative & support | 2021 |
| Eteach Group Services Limited | Professional & scientific | 2011 |
| Eteach International Limited | Professional & scientific | 2011 |
| Eteach UK Limited | Administrative & support | 1999 |
| Eteach.Com Limited | Professional & scientific | 2011 |
| Ethanify Ltd | Real estate | 2023 |