| Dave's Custom Airsoft Ltd | Wholesale & retail | 2014 |
| Daventry Court Residents Association Ltd | Households | 2020 |
| Davi Ryatt Limited | Arts & recreation | 2013 |
| Davidwmarine Services Ltd | Manufacturing | 2025 |
| Davis Property Limited | Real estate | 2015 |
| DAW8 Ltd | Financial services | 2026 |
| Day by Day London Ltd | Wholesale & retail | 2024 |
| Day Precision Engineering Limited | Manufacturing | 2024 |
| DB Precision Repairs Ltd | Manufacturing | 2026 |
| DB Safety Management Limited | Arts & recreation | 2011 |
| DB Services Berkshire Ltd | Administrative & support | 2026 |
| DBF Consulting Ltd | Professional & scientific | 2024 |
| Dbss Berkshire Ltd. | Administrative & support | 2007 |
| DC Accounting Services Ltd | Professional & scientific | 2021 |
| DC Dynamics Solutions Limited | Information & communication | 2011 |
| DCB Build Ltd | Construction | 2019 |
| DCL Drains Ltd | Water & waste | 2016 |
| DCL Pest Control and Rodent Investigation Ltd | Administrative & support | 2024 |
| DCL Pest Control Limited | Administrative & support | 2024 |
| DCT Scuderia Ltd | Wholesale & retail | 2021 |
| DE Groot Consultancy Limited | Health & social care | 2022 |
| DE Sports Provision Limited | Education | 2024 |
| Deal Dock Ltd | Construction | 2025 |
| Debley Solutions Limited | Extraterritorial | 2014 |
| Debra | Health & social care | 2000 |
| Debra Retail Limited | Wholesale & retail | 2011 |
| Debra Trading Limited | Wholesale & retail | 1990 |
| Decobloom Boutique Limited | Hospitality | 2023 |
| Decor Property Ltd | Construction | 2023 |
| Decor Retail Ltd | Wholesale & retail | 2020 |
| Decorace Limited | Construction | 2002 |
| DEE Bizsolutions Limited | Administrative & support | 2025 |
| Deed of Trust Limited | Information & communication | 2011 |
| DEL Data Communications Services Limited | Information & communication | 2014 |
| Dellentra Limited | Information & communication | 2025 |
| Delo-Pellaso Ltd | Transport & logistics | 2023 |
| Delphix Software Limited | Information & communication | 2012 |
| Deluxe Tiling Ltd | Construction | 2025 |
| Denga Digital Limited | Information & communication | 2021 |
| Denigeni Limited | Construction | 2021 |
| Denity Ltd | Transport & logistics | 2016 |
| Denman Investments Limited | Real estate | 2020 |
| Deployflow Ltd | Information & communication | 2010 |
| Design and Build South Limited | Construction | 2021 |
| Design by M Ltd | Other services | 2017 |
| Design Manufacturing Fabrication Ltd | Manufacturing | 2023 |
| Designmore Ltd | Professional & scientific | 2018 |
| Desperate Measures Wargaming Limited | Manufacturing | 2024 |
| Deus Consults Ltd | Professional & scientific | 2009 |
| Devine Blessings Ltd | Wholesale & retail | 2025 |
| Devise Solutions Limited | Information & communication | 2009 |
| Devoted Healthcare Ltd | Administrative & support | 2017 |
| DG Brush Services Ltd | Construction | 2020 |
| DGB Trading Limited | Real estate | 2022 |
| Dgjes Ltd | Transport & logistics | 2024 |
| DI Luca Bike Ltd | Wholesale & retail | 2023 |
| Diamine Limited | Administrative & support | 2018 |
| Diamine-Speciality Inks Limited | Administrative & support | 2003 |
| Diamond Attractions and Events Limited | Arts & recreation | 2025 |
| Diamond Fairground Events Ltd | Hospitality | 2025 |
| Diamond Property Care Ltd | Administrative & support | 2024 |
| Diamond Staffing Solutions Limited | Administrative & support | 2014 |
| Diamond Support Solutions Limited | Administrative & support | 2019 |
| Dibbs Healthcare Ltd | Health & social care | 2012 |
| Diebold Nixdorf (UK) Limited | Manufacturing | 1999 |
| Diens Ltd | Professional & scientific | 2023 |
| Digital D2X LLP | | 2010 |
| Digital Fate AI Limited | Information & communication | 2024 |
| Digital Technology Consulting Limited | Information & communication | 2025 |
| Digity Limited | Professional & scientific | 2005 |
| Dimension & Fact Solutions Ltd | Information & communication | 2010 |
| Dinky Steps Ltd | Professional & scientific | 2024 |
| Dishdale Ltd | Hospitality | 2023 |
| Distribix Ltd | Wholesale & retail | 2026 |
| Ditchling 1964 Limited | Extraterritorial | 2014 |
| Divine Limited | Health & social care | 2013 |
| Divyanshi Consultancy Limited | Information & communication | 2026 |
| Diwell Landscape Designs Limited | Professional & scientific | 2025 |
| DJB Risk Management Ltd | Professional & scientific | 2019 |
| DJE Property Investments Ltd | Real estate | 2025 |
| DJZ Transport Ltd | Administrative & support | 2022 |
| DK Property Invest Ltd | Real estate | 2024 |
| DKB Project Controls Limited | Wholesale & retail | 2010 |
| DKJ Contracts Ltd | Wholesale & retail | 2017 |
| DL Printed Clothing Ltd | Wholesale & retail | 2010 |
| DLC Motors Limited | Wholesale & retail | 2012 |
| Dlvr Ltd | Construction | 2016 |
| DMF Autos Ltd | Wholesale & retail | 2020 |
| DMJ Recycling Ltd | Wholesale & retail | 2021 |
| Doctorizie CIC | Health & social care | 2022 |
| Dodo's Designs Ltd | Manufacturing | 2025 |
| Dog Gone Training Ltd | Other services | 2017 |
| Dogood EDU Limited | Education | 2022 |
| Dogsrus Ltd | Other services | 2025 |
| Dolos Ltd | Professional & scientific | 2020 |
| Doman Harris Limited | Information & communication | 2012 |
| Doman Transport Ltd | Transport & logistics | 2014 |
| Domestic Appliance FIX Ltd | Other services | 2003 |
| Domestic Fire Protection Ltd | Construction | 2026 |
| Domicia Ventures Ltd | Health & social care | 2019 |