| Sarafils Atelier Ltd | Manufacturing | 2026 |
| Sarah Gill Logistics Ltd | Transport & logistics | 2026 |
| Sarah Gill Properties Ltd | Real estate | 2026 |
| Sarah Smith (NW) Limited | Manufacturing | 2026 |
| Sarak Khumar General Trading UK Ltd | Wholesale & retail | 2019 |
| Sardaar JI Tyres Ltd | Wholesale & retail | 2019 |
| Sardar Building Services Ltd | Construction | 2016 |
| Sardar Logistics Ltd | Transport & logistics | 2025 |
| Sardar Surgical Ltd | Wholesale & retail | 2021 |
| Sare Development Limited | Real estate | 2016 |
| Sarooj Construction Ltd | Construction | 2025 |
| Sarpanch & Co Limited | Transport & logistics | 2015 |
| SART4 Ltd | Administrative & support | 2024 |
| Sarum Creative Limited | Information & communication | 2011 |
| SAS (Construction and Restoration) Ltd | Administrative & support | 2009 |
| SAS Clothing Ltd | Wholesale & retail | 2025 |
| SAS Courier Limited | Transport & logistics | 2015 |
| SAS Drain Services (NW) Ltd | Water & waste | 2011 |
| SAS Financial Solutions Limited | Professional & scientific | 2026 |
| SAS Fluid Power Services Limited | Administrative & support | 2015 |
| SAS Fluidpower Ltd | Other services | 2020 |
| SAS Global Distribution Ltd | Administrative & support | 2025 |
| SAS NW Holdings Limited | Financial services | 2025 |
| SAS Solutions Limited | Information & communication | 2009 |
| SAS24 Limited | Real estate | 2024 |
| SAS300 Ltd | Wholesale & retail | 2025 |
| Sasa's Indian Bar & Kitchen Limited | Hospitality | 2024 |
| Sasha Konosonoka Ltd | Transport & logistics | 2025 |
| Sashafoods Ltd | Wholesale & retail | 2016 |
| SAT and KF Logistics Ltd | Transport & logistics | 2025 |
| SAT Pro Limited | Wholesale & retail | 2020 |
| Sata Housing Limited | Real estate | 2022 |
| Satellite World Limited | Information & communication | 2015 |
| Sati Textile Mills Ltd | Manufacturing | 2021 |
| Satomi Nishikigoi Ltd | Agriculture & fishing | 2024 |
| Sattar & Sons (Bolton) Ltd | Wholesale & retail | 2026 |
| Sattar Property Enterprises Ltd | Real estate | 2025 |
| Satti Courier Limited | Transport & logistics | 2024 |
| Saute Styles Limited | Wholesale & retail | 2013 |
| SAV Store 91 Ltd | Wholesale & retail | 2024 |
| Savannah Solutions Ltd | Water & waste | 2025 |
| Savannah Trading Limited | Information & communication | 2016 |
| Savannah's of Lytham Limited | Hospitality | 2025 |
| Save Computers Ltd | Other services | 2020 |
| Save N Sell Estates Limited | Real estate | 2020 |
| Save Peny Ltd | Wholesale & retail | 2022 |
| Save Store Limited | Wholesale & retail | 2025 |
| Savee Ltd | Wholesale & retail | 2024 |
| Savia Consulting Ltd | Professional & scientific | 2018 |
| Saving Threads C.I.C. | Wholesale & retail | 2021 |
| Saviour Holdings Ltd | Financial services | 2026 |
| Saviour Homes Limited | Construction | 2015 |
| Savour Luxe Ltd | Wholesale & retail | 2024 |
| Savro Limited | Wholesale & retail | 2025 |
| Savynee Ltd | Wholesale & retail | 2019 |
| SAW Properties NW Ltd | Real estate | 2021 |
| Sawhney Ventures Limited | Transport & logistics | 2025 |
| Saxon Furniture Limited | Manufacturing | 1981 |
| Saya Centre (Worsley) Ltd | Other services | 2021 |
| Saya Foodstore Ltd | Wholesale & retail | 2024 |
| Saya Smart Ltd | Administrative & support | 2024 |
| Sayara Motors Limited | Wholesale & retail | 2024 |
| Sayem Autocare Limited | Wholesale & retail | 2024 |
| Sayf Property Ltd | Wholesale & retail | 2019 |
| Saylaab Group YK Health Care Limited | Health & social care | 2016 |
| Sayona SK Ltd | Real estate | 2025 |
| SB Bolton Properties Ltd | Real estate | 2022 |
| SB Golf Limited | Arts & recreation | 2017 |
| SB Home Investments Ltd | Real estate | 2025 |
| SB Optical Services Ltd | Health & social care | 2008 |
| SB Tax Ltd | Professional & scientific | 2025 |
| Sb&Co Limited | Wholesale & retail | 2021 |
| SB5 Limited | Financial services | 2014 |
| SBA Consultancy Services Ltd | Administrative & support | 2023 |
| Sbdsp.Delivery Ltd | Transport & logistics | 2024 |
| Sbmj Limited | Wholesale & retail | 2024 |
| Sbpod Properties Ltd | Real estate | 2022 |
| SBT Gearing Solutions Holdings Limited | Financial services | 2026 |
| SBT Gearing Solutions Limited | Wholesale & retail | 2014 |
| SC Group Europe Limited | Arts & recreation | 2024 |
| Scaffolding Supplies North West Ltd | Wholesale & retail | 2024 |
| Scale Europe Ltd | Information & communication | 2024 |
| Scalesexpress Limited | Wholesale & retail | 2013 |
| Scan Computers (UK) Limited | Information & communication | 1993 |
| Scan Digital Dental LAB Limited | Manufacturing | 2022 |
| Scan Forensics Limited | Information & communication | 2008 |
| Scan IT Security 101 Limited | Information & communication | 2008 |
| Scandinavian Content Marketing Ltd | Information & communication | 2023 |
| Scantracer Ltd | Health & social care | 2025 |
| Scarletland Ltd | Wholesale & retail | 2019 |
| Scc-Colyton-It Limited | Information & communication | 2026 |
| Scca Ltd | Professional & scientific | 2008 |
| SCD 1987 Holdings Ltd | Financial services | 2023 |
| Scellis Ltd | Transport & logistics | 2025 |
| Scent Distribution Ltd | Wholesale & retail | 2026 |
| Scentessa Ltd | Wholesale & retail | 2025 |
| Scentories Limited | Wholesale & retail | 2024 |
| Scents @ NO3 Ltd | Wholesale & retail | 2021 |
| Sceptre Care Limited | Administrative & support | 2010 |
| SCH Studio Ltd | Information & communication | 2020 |