| Spectra Roofing Group Ltd | Construction | 2024 |
| SPEEDLIMIT1988 Ltd | Transport & logistics | 2025 |
| Speedway Customs Limited | Wholesale & retail | 2010 |
| Speedwell Real Estate Ltd | Real estate | 2026 |
| Spen Corner Ltd | Hospitality | 2024 |
| Spen Corner Veterinary Centre Limited | Professional & scientific | 2002 |
| Spencer Darwen Holdco Ltd | Financial services | 2025 |
| Spencer Darwen Investments Ltd | Real estate | 2025 |
| Sperrin Solutions Ltd | Construction | 2019 |
| SPG Poulton Properties Limited | Real estate | 2023 |
| Sphp Enterprise Limited | Construction | 2025 |
| Spice Coast Ltd | Hospitality | 2026 |
| Spillane, Sons & Daughters Ltd | Information & communication | 2019 |
| SPIN2WIN Leisure Ltd | Arts & recreation | 2025 |
| Spiro House Limited | Real estate | 1995 |
| Spiteri Ltd | Administrative & support | 2017 |
| Splashreel Media Ltd | Information & communication | 2025 |
| Splitty CUP Limited | Wholesale & retail | 2025 |
| Spongerite International Ltd | Manufacturing | 2015 |
| Spot on Audits Ltd | Other services | 2025 |
| Spotglade Property Management Limited | Households | 1989 |
| Spotless Property Developments Ltd | Administrative & support | 2023 |
| Spoton Car Wash Limited | Administrative & support | 2025 |
| Spring Fountain (Private) Limited | Health & social care | 2014 |
| Springcross Properties Ltd | Real estate | 2024 |
| Springdale Court Limited | Households | 1989 |
| Springfields Personalised Gifts Limited | Wholesale & retail | 2022 |
| Springfields Printing Limited | Wholesale & retail | 2022 |
| Springfields Retail Ltd | Wholesale & retail | 2018 |
| Springfort Developments Ltd | Wholesale & retail | 2025 |
| Sprint Design and Consultancy Ltd | Professional & scientific | 2014 |
| Spurdak Investments Limited | Construction | 2012 |
| Spurlane Limited | Hospitality | 1998 |
| Square 1 Management Consultancy Limited | Professional & scientific | 2018 |
| Squires Gate Football Club Limited | Arts & recreation | 2025 |
| Squires Gents Outfitters (NW) Limited | Wholesale & retail | 2025 |
| Squirrel Close Management Company Limited | Households | 2018 |
| SR & a Thomas Ltd | Health & social care | 2022 |
| SR Design Studio Ltd | Professional & scientific | 2025 |
| SR Sports Consultancy Ltd | Administrative & support | 2017 |
| SR Sports Foundation Ltd | Arts & recreation | 2011 |
| SR Ventilation Limited | Administrative & support | 2014 |
| SRF Trading Limited | Wholesale & retail | 2004 |
| Srinaga Limited | Information & communication | 2016 |
| Srinava Infotech Limited | Information & communication | 2012 |
| SRL Road Maintenance Ltd | Construction | 2025 |
| SS & AP Ltd | Real estate | 2025 |
| SSA Cladding Solutions Ltd | Construction | 2026 |
| Ssbc Holdings Ltd | Financial services | 2019 |
| Ssbc Trading Ltd | Construction | 2019 |
| SSL Pools Limited | Construction | 2009 |
| Ssmm Consultancy Limited | Professional & scientific | 2011 |
| SSP Mart Ltd | Wholesale & retail | 2026 |
| Ssrj Enterprises Limited | Hospitality | 2023 |
| SSS Leisure Ltd | Hospitality | 2024 |
| Ssuco Limited | Professional & scientific | 2015 |
| ST Agnes Capitals & Investments Ltd | Real estate | 2024 |
| ST Andrews Court (Thornton-Cleveleys) Limited | Households | 2002 |
| ST Anne Mini 1 Market Limited | Wholesale & retail | 2025 |
| ST Anne Mini Market Ltd | Wholesale & retail | 2026 |
| ST Audio Visual Limited | Administrative & support | 2026 |
| ST Charles Services Ltd | Construction | 2021 |
| ST Estates Ltd | Real estate | 2023 |
| ST George's Court MC Ltd | Real estate | 2016 |
| ST Hill Engineering & Consulting Services Limited | Professional & scientific | 2017 |
| ST Technology Ltd | Information & communication | 2019 |
| ST Williams Gate Management Company Limited | Households | 2020 |
| ST. Annes Court (Blackpool) Management Company Limited | Households | 1995 |
| ST. Annes Management Limited | Households | 1981 |
| ST. Cuthbert's Court (Lytham) Limited | Households | 1984 |
| ST. James (Anchorsholme) Management Company Limited | Households | 1993 |
| ST. James (Thornton) Management Company Limited | Households | 1994 |
| ST. John's Wood (Lytham) Management Company Limited | Households | 1984 |
| ST. Johns Mews (Blackpool) Limited | Households | 1988 |
| ST. Joseph's Court (Blackpool) Management Company Limited | Households | 1989 |
| ST. Lukes (Blackpool) Management Company Limited | Households | 2003 |
| ST. Margaret's Court (Fleetwood) Limited | Households | 1982 |
| St.Ar Italia Limited | Wholesale & retail | 2019 |
| St.Kentigern's Parish Centre Limited | Hospitality | 1997 |
| ST8 Electrical Ltd | Construction | 2023 |
| Staalco Limited | Construction | 2002 |
| Stabilix AI Ltd | Information & communication | 2023 |
| Staff Benefits Program Ltd | Professional & scientific | 2021 |
| Staff Central Ltd | Administrative & support | 2023 |
| Staffing Solutions Security Ltd | Administrative & support | 2025 |
| Stafford Rainwater Systems Ltd | Construction | 2014 |
| Stafford Shill Ltd | Wholesale & retail | 2025 |
| Stage 3 Property Development Limited | Construction | 2021 |
| Stage 3 Property Investment Limited | Real estate | 2013 |
| Stage Appeal Homes Ltd | Professional & scientific | 2025 |
| Stage Properties UK & EU Ltd | Real estate | 2023 |
| STAGE3 Solutions Ltd | Construction | 2018 |
| Stagebox Ltd | Wholesale & retail | 2016 |
| Stahrs Limited | Professional & scientific | 2006 |
| Staining Lodge Golf Driving Range Ltd | Construction | 2025 |
| Stand - to Ltd | Wholesale & retail | 2025 |
| Stanley Lodge Ltd | Agriculture & fishing | 2023 |
| Stanley Ward Conservative Club Limited | Hospitality | 1949 |
| Stantons Holding Ltd | Financial services | 2020 |
| Star Chef Oriental Lancashire Ltd | Hospitality | 2025 |