| DK Vapes Ltd | Wholesale & retail | 2020 |
| DKD Homes Limited | Manufacturing | 2021 |
| DKD Project Solutions Ltd | Professional & scientific | 2016 |
| Dkharwood Ltd | Professional & scientific | 2026 |
| DKT Solutions Limited | Information & communication | 2013 |
| DLB Facilities Management Ltd | Construction | 2026 |
| DLE Hospitality Ltd | Hospitality | 2019 |
| DLW Plumbing & Heating Ltd | Construction | 2020 |
| DM & M Consultancy Services Ltd | Professional & scientific | 2017 |
| DM (NW) Holdings Ltd | Financial services | 2025 |
| DM Vehicle Repairs (NW) Ltd | Wholesale & retail | 2025 |
| DMA Logistics (NW) Ltd | Administrative & support | 2020 |
| Dmck Consulting Ltd | Information & communication | 2024 |
| DMP Services Ltd | Information & communication | 2019 |
| DNM Holdings Ltd | Real estate | 2025 |
| Dobson & Beaumont (Holdings) Limited | Financial services | 2021 |
| Dobson & Beaumont Limited | Manufacturing | 1978 |
| Dock Lights UK Limited | Manufacturing | 2025 |
| Dogarbrothers Limited | Wholesale & retail | 2024 |
| Dollar B Ltd | Wholesale & retail | 2024 |
| Dollar MAN Limited | Wholesale & retail | 2026 |
| Dollys Cafe Ltd | Hospitality | 2021 |
| Domcans Limited | Construction | 2021 |
| Domestic Appliances Shield Ltd | Other services | 2025 |
| Domestic Gaserve Ltd | Administrative & support | 2018 |
| Domestic Grants UK Ltd | Professional & scientific | 2024 |
| Domestic Utilities Services Ltd | Professional & scientific | 2015 |
| Dominic Boyle Limited | Transport & logistics | 2016 |
| DON Dough Ltd | Hospitality | 2024 |
| Donelan Trading Limited | Financial services | 1981 |
| Doney Properties Ltd | Real estate | 2019 |
| Doney Timbers Limited | Manufacturing | 1985 |
| Doodle Press Ltd | Arts & recreation | 2023 |
| Door to Door Care Ltd | Health & social care | 2024 |
| Doppel Krone Services UK Ltd | Information & communication | 2024 |
| Dora and Co Pooch Boutique Ltd | Wholesale & retail | 2021 |
| Doro Care (UK) Limited | Health & social care | 2013 |
| Double a Discount Ltd | Manufacturing | 2025 |
| Double a Eight Limited | Wholesale & retail | 2023 |
| Double Storey Ltd | Construction | 2020 |
| Douglas Global Commerce Ltd | Wholesale & retail | 2025 |
| Douglas Signs Limited | Manufacturing | 2003 |
| Downham Associates Group Ltd | Financial services | 2024 |
| Downham Associates Ltd | Professional & scientific | 2021 |
| Downham Holdings Ltd | Financial services | 2024 |
| Downham Payroll Services Ltd | Professional & scientific | 2024 |
| Dowson Housing Ltd | Real estate | 2023 |
| Dowsons Dairies Ltd | Administrative & support | 2002 |
| DOX2YOU Limited | Administrative & support | 2014 |
| Doxiacare Limited | Public administration | 2021 |
| DPF Problems Ltd | Wholesale & retail | 2025 |
| DPM Accounting Services Ltd | Professional & scientific | 2005 |
| DPM Consultancy & Academy Ltd | Professional & scientific | 2021 |
| DR Arsh Ltd | Other services | 2019 |
| DR Comps Ltd | Wholesale & retail | 2023 |
| DR Gigi Ltd | Wholesale & retail | 2026 |
| DR M B Aslam Ltd | Health & social care | 2010 |
| DR PRD Humphrey Ltd | Other services | 2013 |
| DR Sabiha Sheikh Limited | Health & social care | 2020 |
| DR Simona Aesthetics Ltd | Health & social care | 2021 |
| DR SM Consulting Ltd | Health & social care | 2013 |
| DR Sonde Ltd | Health & social care | 2017 |
| DR Youssef Ltd | Health & social care | 2025 |
| DR ZA Ltd | Health & social care | 2021 |
| DR Zain Ahmed Ltd | Other services | 2024 |
| DR. Indra Fmgp Limited | Health & social care | 2017 |
| Dragons DEN Fancy Dress Limited | Wholesale & retail | 2016 |
| DRE Homewares Ltd | Wholesale & retail | 2024 |
| Dream Enterprises Ltd | Wholesale & retail | 2020 |
| Dream Homes Developers Ltd | Construction | 2025 |
| Dream Media Interactive Ltd | Information & communication | 2018 |
| Dream Media Ltd | Extraterritorial | 2003 |
| Dream Media Marketing Ltd | Information & communication | 2003 |
| Dream Media Services Ltd | Information & communication | 2025 |
| Dreamfall Holdings Limited | Financial services | 2020 |
| Dreamfall Investments Limited | Real estate | 2020 |
| Dreamfall Medical Limited | Health & social care | 2014 |
| Dreams & Details Ltd | Professional & scientific | 2025 |
| Dreams Travel & Cargo Services Ltd | Transport & logistics | 2023 |
| Dreamzz Limited | Wholesale & retail | 2024 |
| Dressed Boutique Limited | Wholesale & retail | 2021 |
| Drhm Ltd | Real estate | 2021 |
| Drin-Kit Ltd | Wholesale & retail | 2020 |
| Drinklight Ltd | Real estate | 2022 |
| Dripmodauk Ltd | Wholesale & retail | 2021 |
| Drive Thru Medics Ltd | Health & social care | 2024 |
| Driverhelpline Ltd | Administrative & support | 1998 |
| Drivestaff Recruitment Ltd | Administrative & support | 2026 |
| Drivin' Guru Ltd | Education | 2018 |
| DRM Development Group Ltd | Real estate | 2025 |
| Drmp Medical Limited | Health & social care | 2013 |
| Drone's EYE View Limited | Information & communication | 2025 |
| DRS Developments (NW) Limited | Construction | 2024 |
| Drummond Consultancy Limited | Professional & scientific | 2023 |
| DS Auto Sales Limited | Wholesale & retail | 2026 |
| DS Drill Cost Limited | Professional & scientific | 2013 |
| DS Shuttleworth Ltd | Transport & logistics | 2025 |
| DS4U Investments Limited | Wholesale & retail | 2021 |
| DSF Bearings and Power Transmissions Limited | Wholesale & retail | 2014 |
| DSM CA Limited | Professional & scientific | 2008 |