| Designscape Media Ltd | Professional & scientific | 2024 |
| DESPAIR2HOPE CIC | Health & social care | 2009 |
| Dessert Garden Limited | Hospitality | 2025 |
| Destination Perfect Limited | Administrative & support | 2018 |
| Detailing Clinic Ltd | Administrative & support | 2022 |
| Devine Doors Limited | Construction | 2024 |
| Devjam Properties Ltd | Financial services | 2025 |
| Devonshire Street Limited | Wholesale & retail | 2012 |
| Devote Associates Ltd | Professional & scientific | 2007 |
| DEW Bar Europe Ltd | Wholesale & retail | 2021 |
| Dewric Limited | Manufacturing | 1970 |
| Dexcloud Ltd | Professional & scientific | 2022 |
| Dexter Decorative Supplies Ltd | Wholesale & retail | 2008 |
| Deyaan ALI Ltd | Wholesale & retail | 2023 |
| Dezato Blackburn Ltd | Hospitality | 2024 |
| DF Plumbing and Heating Ltd | Construction | 2022 |
| DF Wholesale Ltd | Wholesale & retail | 2025 |
| DFC Enterprise Ltd | Hospitality | 2017 |
| Dfsl Holdings Ltd | Professional & scientific | 2015 |
| DFX Consulting Ltd | Wholesale & retail | 2021 |
| Dgch Holdings Limited | Administrative & support | 2017 |
| DGW Investments Limited | Real estate | 2014 |
| DGW Trading Company Ltd | Wholesale & retail | 2024 |
| DH Builders RV Ltd | Construction | 2020 |
| DH Medical Group Ltd | Other services | 2020 |
| DH Medical Ltd | Other services | 2024 |
| DH Properties Investment Ltd | Other services | 2024 |
| DH Sports Consultancy Ltd | Arts & recreation | 2019 |
| DH Tiling & Bathrooms Ltd | Construction | 2026 |
| DH Waterside Ltd | Real estate | 2024 |
| DHI Logistics Ltd | Transport & logistics | 2026 |
| Dhila Enterprise Ltd | Wholesale & retail | 2022 |
| Dhillam Travel and Tours Ltd | Administrative & support | 2023 |
| Dhorat Store Limited | Wholesale & retail | 2022 |
| Diagnostic Discounts Ltd | Wholesale & retail | 2026 |
| Diakonia Services Ltd | Construction | 2026 |
| Diamond Estate Agents Ltd | Real estate | 2010 |
| Diamond Media Productions Ltd | Information & communication | 2022 |
| Diamond Property Hub Limited | Real estate | 2024 |
| Diamond Rims Ltd | Wholesale & retail | 2015 |
| Diamond Turkish UK Barber Ltd | Other services | 2026 |
| Diamond Vehicle Solutions Blackburn Ltd | Wholesale & retail | 2025 |
| Dickens Court Residents Limited | Real estate | 2025 |
| Dickinson Connect Group Limited | Administrative & support | 2025 |
| Diddly Dots Farm Shop Ltd | Wholesale & retail | 2026 |
| Dietech Engineering Company Limited | Manufacturing | 2003 |
| Digi Optimization Ltd | Professional & scientific | 2025 |
| Digibridge Solutions Ltd | Information & communication | 2025 |
| Digiswift Ltd | Wholesale & retail | 2024 |
| Digital Media Matrix Ltd | Information & communication | 2025 |
| Digital Printing Systems UK Ltd | Manufacturing | 2023 |
| Digitalfoodfactory Ltd | Professional & scientific | 2020 |
| Digitech Trading Limited | Wholesale & retail | 2017 |
| Digivoo Limited | Wholesale & retail | 2023 |
| Dile Communications Limited | Information & communication | 2024 |
| Dillon and Hopkinson Properties Limited | Professional & scientific | 2020 |
| Dilnaz-Investment Group Ltd | Real estate | 2022 |
| DIN Brothers Ltd | Wholesale & retail | 2023 |
| Dinckley Grange Produce Ltd | Agriculture & fishing | 2019 |
| Dinner Lady FAM Ltd | Manufacturing | 2016 |
| Dinner Lady Holdings Ltd | Financial services | 2023 |
| Dinomic Games Ltd | Information & communication | 2026 |
| Diplomatic Security Services & Anti-Drugs ONG Ltd | Public administration | 2023 |
| Dipz Limited | Manufacturing | 2019 |
| Direct Claims Advice Limited | Other services | 2011 |
| Direct Corporate North West Ltd | Extraterritorial | 2022 |
| Direct Courier Solutions Ltd | Transport & logistics | 2024 |
| Direct Data Capture Limited | Information & communication | 1989 |
| Direct Foam and Packaging Limited | Administrative & support | 2013 |
| Direct Furniture Suppliers Ltd | Wholesale & retail | 2012 |
| Direct K9 Solutions Ltd | Administrative & support | 2024 |
| Direct Motor Spares Ltd | Wholesale & retail | 2020 |
| Direct Netting & Scaffolding Ltd | Construction | 2017 |
| Direct Sips Ltd | Construction | 2024 |
| Direct Windows (Blackburn) Limited | Manufacturing | 1995 |
| Directxl Limited | Administrative & support | 2013 |
| Dirty Dust Limited | Manufacturing | 2026 |
| Dis-Labelled C.I.C. | Wholesale & retail | 2019 |
| Disc Traders Ltd | Wholesale & retail | 2024 |
| Disco Cars and Minibuses Ltd | Transport & logistics | 2017 |
| Discountdelights Ltd | Wholesale & retail | 2023 |
| Discounthubuk Ltd | Wholesale & retail | 2026 |
| Distinguished Beauty Limited | Wholesale & retail | 2018 |
| Distro Direct Furniture Ltd | Wholesale & retail | 2026 |
| Divano Italia Limited | Wholesale & retail | 2019 |
| Divano Limited | Wholesale & retail | 2019 |
| Diveli Group Ltd | Professional & scientific | 2024 |
| Diverse Cooling Solutions Ltd | Energy | 2011 |
| Divine Ladies Association Limited | Other services | 2017 |
| Divine Products Ltd | Manufacturing | 2025 |
| Diwan Investment Group Limited | Real estate | 2026 |
| Dixy Super Limited | Hospitality | 2024 |
| DIY Projects Ltd | Construction | 2023 |
| DJ Hayfield & Co Ltd | Real estate | 2025 |
| DJ Precision Engineering Ltd | Manufacturing | 2013 |
| Django Enterprises Ltd | Wholesale & retail | 2019 |
| DJS Properties (Lancs) Limited | Real estate | 2026 |
| DK Capelli Holdings Ltd | Financial services | 2020 |
| DK Eyewear Ltd | Wholesale & retail | 2024 |
| DK Management Services Ltd | Administrative & support | 2024 |