| Craze Solar Ltd | Energy | 2023 |
| Creedy Lakes Ltd | Agriculture & fishing | 2026 |
| Creighton Hooper Limited | Professional & scientific | 2003 |
| Crimp Holdings Limited | Financial services | 2025 |
| Croft & Company Independent Financial Advisers Limited | Financial services | 2025 |
| Crossfit LDN Limited | Arts & recreation | 2014 |
| Crossfit Nottingham Limited | Arts & recreation | 2013 |
| Crouch and Sons Ltd | Real estate | 2024 |
| Crow Bar Ltd | Wholesale & retail | 2022 |
| Crown Security Solutions Limited | Administrative & support | 2013 |
| CTB Energy Services Ltd | Construction | 2025 |
| Cubiq Ltd | Information & communication | 2020 |
| CUE Sports Academy Ltd | Hospitality | 2024 |
| Culm Valley Farm & Industrial Buildings Limited | Construction | 2002 |
| Cunningham Renovations Ltd | Construction | 2023 |
| Cycles Scuderia Limited | Wholesale & retail | 2014 |
| D & a Vehicles Limited | Wholesale & retail | 2021 |
| D Beer Limited | Construction | 2001 |
| D Prouse Plumbing & Heating Engineers Ltd | Construction | 2011 |
| D R Tiling LLP | | 2019 |
| D Scott Financial Limited | Financial services | 2020 |
| D Shuttleworth Engineering Services Limited | Professional & scientific | 2003 |
| D&D Taxis Limited | Transport & logistics | 2021 |
| D.P. Agri Limited | Manufacturing | 2007 |
| DAC Project Management Ltd | Construction | 2025 |
| Daddon Court Management Ltd | Real estate | 2010 |
| Daisy Chain Devon Community Projects Ltd | Health & social care | 2025 |
| Daisy Chain Social Activity Group Ltd | Health & social care | 2020 |
| Daleys Travel Limited | Wholesale & retail | 2024 |
| Dappe Ltd | Real estate | 2022 |
| DARE2BU Limited | Other services | 2021 |
| Dark Neon Limited | Information & communication | 2001 |
| Dave Baskerville Auto Services Limited | Wholesale & retail | 2005 |
| Davey Construction (SW) Ltd | Construction | 2019 |
| David Celaschi Limited | Health & social care | 2012 |
| David Wilson Partnership Limited | Professional & scientific | 2012 |
| Daw's Clothing Company Ltd | Wholesale & retail | 2021 |
| Dawla Ltd | Construction | 2023 |
| DB Hughes Security Ltd | Administrative & support | 2024 |
| DC Dynamic Construction Ltd | Construction | 2025 |
| Dced Ltd | Administrative & support | 2015 |
| DCN Developments Ltd | Construction | 2022 |
| Deborah Somerville Chartered Architect LLP | | 2019 |
| Decorworks Ltd | Construction | 2011 |
| Deepest Green( Agri Lignum) Limited | Wholesale & retail | 2023 |
| Delve Estates Limited | Administrative & support | 2008 |
| Delve House Limited | Real estate | 2008 |
| Demohouse Limited | Agriculture & fishing | 1995 |
| Devon & Cornwall Fish Company Ltd | Wholesale & retail | 2020 |
| Devon Autogyro Ltd | Arts & recreation | 2012 |
| Devon Bodywork Limited | Wholesale & retail | 2004 |
| Devon Civils & Utilities Limited | Construction | 2023 |
| Devon Film Logistics Limited | Administrative & support | 2020 |
| Devon Firewood Limited | Wholesale & retail | 2022 |
| Devon Hotel Limited | Professional & scientific | 1997 |
| Devon Laser Clinic Limited | Health & social care | 2008 |
| Devon Minimarket (MS) Ltd | Wholesale & retail | 2026 |
| Devon PUB Group Limited | Hospitality | 2025 |
| Devon Self Storage Ltd | Administrative & support | 2024 |
| Devon Surgical Services Ltd | Health & social care | 2025 |
| Devon Technology Services LLP | | 2020 |
| Devon Transport Training Limited | Extraterritorial | 1974 |
| Devon Village Properties Ltd | Construction | 2016 |
| Devonia Escapes LLP | | 2021 |
| Devons Spice Ltd | Hospitality | 2020 |
| Devonshire Pine (Holdings) Limited | Financial services | 2018 |
| Devonshire Pine Limited | Wholesale & retail | 1992 |
| Dewar White's Ltd | Health & social care | 2018 |
| Dezzy Design Limited | Professional & scientific | 2010 |
| Dfll Holdings Limited | Financial services | 2024 |
| DG Motor Services (ND) Ltd | Wholesale & retail | 2019 |
| Diba Limited | Extraterritorial | 2002 |
| Dirty Bite Food Ltd | Hospitality | 2026 |
| Disabilityengagementservices Limited | Administrative & support | 2023 |
| Discovering the Power of YOU Limited | Other services | 2016 |
| Diverse Living Devon Ltd | Health & social care | 2024 |
| Dividesurvey Projects Limited | Real estate | 1993 |
| DJC Civil Engineering Services Ltd | Professional & scientific | 2015 |
| DK Cars and Commercials Limited | Wholesale & retail | 2023 |
| DK East Ltd | Hospitality | 2024 |
| DK Engineering (South West) Ltd | Construction | 2016 |
| DK West Limited | Hospitality | 2017 |
| DMC Building Solutions Ltd | Construction | 2025 |
| DMC Roofing & Leadworks Ltd | Construction | 2020 |
| DMG Devon Limited | Real estate | 2023 |
| Doggies GOT Style Limited | Other services | 2022 |
| Dollymal's Kitchen Ltd | Manufacturing | 2025 |
| Dolphin Court Residents Association Limited | Real estate | 1968 |
| Dolton Designs Ltd | Manufacturing | 2024 |
| Domain 5 Ltd | Professional & scientific | 2025 |
| Domeverte Ltd | Wholesale & retail | 2026 |
| DOT Adventures Limited | Information & communication | 2019 |
| Dovey Cottages Limited | Extraterritorial | 2008 |
| DP Windows North Devon Ltd | Construction | 2014 |
| DR. Homes London Ltd | Construction | 2012 |
| Drayton Residents Company Limited | Households | 1995 |
| Drysafe Construction Limited | Construction | 2007 |
| Dtec Pro Ltd | Construction | 2019 |
| Dunn & Carter Ltd | Real estate | 2020 |
| Duntz Valley Shoot Limited | Administrative & support | 2005 |