| EP Cinderella Cleaning Service Ltd | Administrative & support | 2016 |
| Equa Clinic Limited | Other services | 2026 |
| Espere Leadership Limited | Other services | 2023 |
| Ethoss Limited | Information & communication | 2016 |
| European Shop Yeovil Ltd | Wholesale & retail | 2019 |
| EV Transport UK Ltd | Transport & logistics | 2020 |
| EVA 2024 Cleaning Ltd | Administrative & support | 2024 |
| Event Wine Brands Limited | Professional & scientific | 2024 |
| Event Wine Solutions Limited | Wholesale & retail | 2013 |
| Ever SO Clean Supplies Limited | Wholesale & retail | 2002 |
| Evercreech Park Farms Limited | Agriculture & fishing | 2005 |
| Everkind Home Care Limited | Health & social care | 2025 |
| Everton Road YEO Ltd | Households | 2023 |
| Evolver Media Limited | Information & communication | 2009 |
| Eweleaze Services Limited | Agriculture & fishing | 2005 |
| EWH Investments Ltd | Administrative & support | 2018 |
| Executive Vehicle Hire Limited | Transport & logistics | 2018 |
| Exeter Bike Park Ltd | Arts & recreation | 2025 |
| Exped VET Ltd | Professional & scientific | 2024 |
| EZI Gold Digital Marketing Ltd | Professional & scientific | 2025 |
| F L Plastering Group Ltd | Construction | 2025 |
| F. R. Bartlett Limited | Extraterritorial | 1958 |
| F5 DEV Limited | Information & communication | 2025 |
| Face IT Yeovil Limited | Manufacturing | 2016 |
| Fair Play Gaming Ltd. | Information & communication | 2017 |
| Fairfield Montessori School Limited | Education | 2010 |
| Fairview Haulage Limited | Transport & logistics | 2008 |
| Falkland House Management Limited | Households | 1988 |
| Family Assessment and Support Services Limited | Professional & scientific | 2010 |
| Fareham Energy Reserve 2 Limited | Construction | 2019 |
| Fareham Energy Reserve Limited | Construction | 2018 |
| Farthing Place Management Company (NO. 2) Limited | Households | 2004 |
| Fast Feedback Limited | Education | 2024 |
| FAT Shaun's Limited | Hospitality | 2012 |
| FBA by Motunz Ltd | Wholesale & retail | 2021 |
| FCG Agriculture Limited | Agriculture & fishing | 1997 |
| Fejza International Limited | Wholesale & retail | 2022 |
| FEP Ltd | Extraterritorial | 2022 |
| Fermis Limited | Professional & scientific | 2015 |
| FHS24 Nursing+Care Agency Ltd | Health & social care | 2017 |
| Fiberworx Limited | Manufacturing | 2013 |
| Fibrillogenesis Ltd | Professional & scientific | 2019 |
| Field Bars House RTM Company Ltd | Real estate | 2012 |
| Field Design Management Limited | Professional & scientific | 2020 |
| Fierro International Limited | Wholesale & retail | 2021 |
| Filinvest Estates Ltd | Real estate | 2023 |
| Finch Aviation Ltd | Professional & scientific | 2021 |
| Findlay Orthopaedics Limited | Health & social care | 2017 |
| Finesse Telecommunications Limited | Extraterritorial | 2020 |
| Finessia Ltd | Information & communication | 2026 |
| Finexperts Limited | Professional & scientific | 2013 |
| Finnventory Ltd | Wholesale & retail | 2025 |
| Fire Safety Partnership Ltd | Professional & scientific | 2007 |
| Firestone Surfacing Limited | Administrative & support | 2007 |
| Firmstake Limited | Financial services | 2009 |
| First AID Trainer Hub Ltd | Education | 2024 |
| First Class Improvements Limited | Construction | 2022 |
| First Revolution Engineering Management Solutions Ltd | Professional & scientific | 2019 |
| First Steps (Yeovil) Ltd | Health & social care | 2022 |
| First Wave International Certification Ltd | Professional & scientific | 2025 |
| Fission Fitness Limited | Administrative & support | 2017 |
| Fit & Furnish Limited | Wholesale & retail | 2009 |
| Fit Line Ltd | Manufacturing | 2025 |
| Fitness Yeovil by Rustypt Ltd | Arts & recreation | 2022 |
| Five Trees in Somerset Limited | Hospitality | 2021 |
| Fiveways Ventures Ltd | Information & communication | 2015 |
| Fixerup UK Ltd | Manufacturing | 2023 |
| FJD Haulage (London) Limited | Transport & logistics | 2015 |
| Flacko Ltd | Health & social care | 2018 |
| Flavourich Limited | Manufacturing | 2026 |
| Flaydemouse Media Limited | Manufacturing | 2011 |
| Fleetwood Grab Services Limited | Construction | 2007 |
| Fleetwood Recycling Limited | Water & waste | 2011 |
| Flight Dynamic Engineering Limited | Professional & scientific | 2023 |
| Floorworkz Limited | Construction | 2019 |
| FLY Navy Heritage Trust Limited | Arts & recreation | 2006 |
| FM Permanent Cosmetics Ltd | Other services | 2019 |
| Focus Care 24/7 Ltd | Administrative & support | 2020 |
| Focus on Change Limited | Information & communication | 2007 |
| Foot Control Limited | Health & social care | 2016 |
| Forge Environmental Management Limited | Professional & scientific | 2012 |
| Fortress Construction Consultancy Ltd | Construction | 2025 |
| Fosse (Yeovil) RTM Company Limited | Extraterritorial | 2004 |
| Fosse Way RTM Company Limited | Households | 2018 |
| Foulis Holdings Ltd | Construction | 2022 |
| Foulis Property Investments Ltd | Construction | 2022 |
| Foxmeadows Limited | Other services | 2014 |
| Francella Estates Ltd | Construction | 2026 |
| Francis DE Lara Limited | Wholesale & retail | 2017 |
| Freedom Forward Ventures Ltd | Information & communication | 2024 |
| Freedom Phones Ltd | Manufacturing | 2018 |
| Freelance Computer Programmers Ltd | Information & communication | 2019 |
| Frendy Integrated Services Ltd | Administrative & support | 2014 |
| Freshstores Limited | Wholesale & retail | 1993 |
| Friends of Yeovil Hospital Shop Limited | Wholesale & retail | 1991 |
| Frizzle Farm Contracting Ltd | Agriculture & fishing | 2018 |
| FSP Property Ltd | Real estate | 2026 |
| Ftahirs Ltd | Health & social care | 2014 |
| FULFILMENT4YOU Ltd | Wholesale & retail | 2023 |
| Function Central Limited | Arts & recreation | 2007 |