| Ecclesden Farm Ltd | Hospitality | 2022 |
| Ecclesden Storage Ltd | Transport & logistics | 2025 |
| ECE Architecture Limited | Professional & scientific | 1989 |
| ECE Group Limited | Financial services | 2014 |
| ECE Investments Ltd | Real estate | 2019 |
| ECE Planning Limited | Professional & scientific | 2011 |
| ECE Westworks Limited | Professional & scientific | 2015 |
| ECH Consulting Limited | Administrative & support | 2024 |
| ECH03DGE Media Limited | Information & communication | 2024 |
| Ecila Ltd | Information & communication | 2020 |
| Eclectic Home Ltd | Wholesale & retail | 2024 |
| Eco Recruitment Group Limited | Administrative & support | 2018 |
| Eco-Warmth Mechanical Limited | Construction | 2021 |
| Ecoclear Limited | Professional & scientific | 1991 |
| Ecofar UK Limited | Administrative & support | 2007 |
| Econe Energy Limited | Construction | 2024 |
| Ecoversal Ltd | Information & communication | 2021 |
| Eddie Frazer Towers Ltd | Real estate | 2020 |
| Eden Clinical Services Limited | Health & social care | 2014 |
| Eden Tree Surgery Limited | Agriculture & fishing | 2023 |
| Edenia Care Limited | Health & social care | 2024 |
| Edge Digital Manufacturing Limited | Information & communication | 2018 |
| Edible Assets Limited | Extraterritorial | 2016 |
| Edster Court Limited | Households | 2019 |
| Educate U Futures Limited | Education | 2024 |
| Educateuwestsussex Ltd | Education | 2019 |
| Educating Gently Ltd | Education | 2022 |
| Education Futures Ltd | Professional & scientific | 2017 |
| Educo Advisory Limited | Professional & scientific | 2016 |
| Educo Holiday Clubs Limited | Education | 2015 |
| Edwards and Co (Estate Agents) Limited | Real estate | 2008 |
| Eerieissss Limited | Information & communication | 2022 |
| EF Craft Spirits Ltd | Manufacturing | 2016 |
| EF Estates Limited | Real estate | 2023 |
| Efes Town Restaurant Ltd | Hospitality | 2023 |
| Efesim Restaurant Ltd | Hospitality | 2018 |
| Effdot Limited | Information & communication | 2020 |
| Effizen Consulting Ltd | Professional & scientific | 2020 |
| Effpark Two Ltd | Real estate | 2014 |
| Efjays Limited | Construction | 2005 |
| EFQ Crosby and Associates Limited | Administrative & support | 2025 |
| EFS Supplies Limited | Wholesale & retail | 2022 |
| EG Systems (UK) Limited | Professional & scientific | 2013 |
| EGG Ventures Limited | Wholesale & retail | 2021 |
| EGY Traditional Dessert Ltd | Hospitality | 2026 |
| EIB Music Limited | Arts & recreation | 2016 |
| Eighty Nine Church Road Limited | Households | 2026 |
| Eileen SAY Catering Equipment Limited | Construction | 1996 |
| EJ Humphrey Ltd | Administrative & support | 2025 |
| EKO UK Limited | Information & communication | 2008 |
| EL Callao Holding Ltd | Financial services | 2017 |
| EL8 Estates Ltd | Real estate | 2023 |
| Eland Haven Limited | Health & social care | 2015 |
| Elanip Holdings Ltd | Real estate | 2022 |
| Elanip Ltd | Information & communication | 2014 |
| ELB Investment Property Limited | Real estate | 2018 |
| ELB Lifestyle Solutions Ltd | Real estate | 2015 |
| ELB Property Holding Limited | Real estate | 2016 |
| Elcafe Limited | Hospitality | 2025 |
| Elcogen Group Limited | Other services | 2021 |
| Elderhart Limited | Construction | 2004 |
| Eldon Properties Limited | Real estate | 2013 |
| Eldonstone Limited | Hospitality | 1975 |
| Eleanor Barber Publishing Services Limited | Administrative & support | 2023 |
| Elearning Network Community Interest Company | Other services | 2009 |
| Electra-Tec (Southern) Limited | Construction | 2010 |
| Electric Light Studios Ltd | Arts & recreation | 2010 |
| Electricity Pensions Limited | Financial services | 1989 |
| Electricity Pensions Services Limited | Financial services | 1995 |
| Electricity Pensions Trustee Limited | Professional & scientific | 1990 |
| Electronic Temperature Instruments Limited | Manufacturing | 1983 |
| Element Integrated Contracts Ltd | Other services | 2019 |
| Element Sauna Ltd | Arts & recreation | 2025 |
| Elephant Homes CIC | Real estate | 2020 |
| Elevate Loft Works & Construction Ltd | Construction | 2025 |
| Elevate Solar Energy Limited | Construction | 2026 |
| Elevationtrack Limited | Manufacturing | 2025 |
| Eleven Eleven Entertainment Limited | Information & communication | 2020 |
| Elexconnect Contractors Limited | Construction | 2018 |
| ELI Hope Ltd | Real estate | 2019 |
| Elias & Samir Ltd | Other services | 2019 |
| Elite Brickwork and Construction Ltd | Construction | 2025 |
| Elite Build West Sussex Ltd | Construction | 2021 |
| Elite Electrical Sussex Ltd | Construction | 2023 |
| Elite Landscaping Southern Ltd | Construction | 2023 |
| Elite Pro Support Ltd | Administrative & support | 2024 |
| Elite Project Delivery Ltd | Professional & scientific | 2014 |
| Elite Sports Coaching CIC | Education | 2024 |
| Elite U.S. Academy Ltd | Arts & recreation | 2021 |
| Elite Wills & Estate Planning LLP | | 2012 |
| Eliza Browne Limited | Professional & scientific | 2025 |
| Elizabeth Atkinson Psychology Ltd | Education | 2025 |
| ELK Collective Co Ltd | Information & communication | 2025 |
| Elkington & Co.,Limited | Extraterritorial | 1907 |
| Elkington Mansill Booth Limited | Extraterritorial | 1920 |
| Ellaza Ltd | Real estate | 2018 |
| Ellen Atkinson Limited | Education | 2011 |
| Ellett Mechanical Ltd | Construction | 2025 |
| Ellice Training Limited | Education | 2012 |
| Elliroux Investments Ltd | Real estate | 2019 |