| Spitfire Speed Shop Ltd | Wholesale & retail | 2019 |
| Split Second Holdings Limited | Financial services | 2025 |
| Split Second Research Limited | Information & communication | 2015 |
| Split Second Software Limited | Information & communication | 2025 |
| Splitfin Ltd | Information & communication | 2025 |
| Sponge Rebels Limited | Wholesale & retail | 2025 |
| Sporting Legacies Limited | Wholesale & retail | 2023 |
| Sports Partnership Herefordshire and Worcestershire | Arts & recreation | 2013 |
| Sports Vehicle Performance Limited | Wholesale & retail | 2023 |
| Spot on Cleaning & Security Ltd | Administrative & support | 2022 |
| Spotless Cleaners Commercial Ltd | Administrative & support | 2025 |
| Spotlight Consulting Ltd | Professional & scientific | 2013 |
| SPR Trees and Landscapes Limited | Administrative & support | 2025 |
| Sprecher Grier Limited | Extraterritorial | 2019 |
| Spring Core Solution Ltd | Professional & scientific | 2026 |
| Spring Lane Moulders Limited | Manufacturing | 1953 |
| Spring Proms Limited | Extraterritorial | 2005 |
| Spring Valley Construction Ltd. | Construction | 2018 |
| Springbokmovingservice Ltd | Transport & logistics | 2024 |
| Springfield 1970 Limited | Extraterritorial | 2015 |
| Springfield Fast Food Ltd | Hospitality | 2025 |
| Springpack Holdings Limited | Professional & scientific | 2013 |
| Springpack Limited | Administrative & support | 2013 |
| Spry Group Limited | Professional & scientific | 2023 |
| Spv-Erks Limited | Administrative & support | 2026 |
| Square Edge Ltd | Construction | 2024 |
| SQUARE1 Energy Limited | Energy | 2017 |
| Squires-Clark & Co Limited | Professional & scientific | 2025 |
| SR Properties 97 Limited | Real estate | 2024 |
| Ssgp Ltd | Hospitality | 2026 |
| ST Faith's Road Management Company Limited | Households | 1983 |
| ST George's Mews Management Company Limited | Households | 2005 |
| ST James Close (Welland) Management Company Ltd | Households | 2020 |
| ST James Street Holding Ltd | Real estate | 2026 |
| ST Johns Carpets Ltd | Wholesale & retail | 2023 |
| ST Johns Garage Limited | Wholesale & retail | 2011 |
| ST Johns Local Store Ltd | Wholesale & retail | 2025 |
| ST Kenelm Court Management Company Limited | Extraterritorial | 2006 |
| ST Kitchen Ltd | Hospitality | 2025 |
| ST Martins Court Management (NO 2) Limited | Hospitality | 1994 |
| ST Marys Hall (Bromsgrove) Limited | Households | 2026 |
| ST Paul's Hostel | Health & social care | 1995 |
| ST Pauls Church Worcester | Other services | 2014 |
| ST Peter's Animal Clinic Limited | Professional & scientific | 2019 |
| ST Peters Nurseries Holdings Limited | Administrative & support | 2004 |
| ST Peters Nurseries Limited | Wholesale & retail | 1994 |
| ST Philomena's Medical Services Ltd | Health & social care | 2023 |
| ST. Albans Mount Management Limited | Real estate | 1990 |
| ST. Barts Financial Planning Ltd | Financial services | 2026 |
| ST. Mary's Court (Sansome Walk) Limited | Real estate | 2005 |
| ST. Piran's Health Care Limited | Financial services | 2007 |
| ST. Richard S Hospice Trading Company Limited | Wholesale & retail | 2003 |
| ST. Richard's Hospice Foundation | Health & social care | 1984 |
| St.Stephen's (H.C.) Limited | Construction | 2010 |
| ST3 Consulting Limited | Professional & scientific | 2012 |
| Stable Lettings Limited | Real estate | 2021 |
| Stablemates Tewkesbury Ltd | Education | 2024 |
| Stables & Boughton Properties Ltd | Real estate | 2018 |
| Staffcheck Ltd | Information & communication | 2015 |
| Stage Lighting Solutions Ltd | Arts & recreation | 2015 |
| Stainless Steel Products Limited | Wholesale & retail | 2021 |
| Stalanna Homes Limited | Construction | 2006 |
| Stallard March and Edwards LLP | | 2010 |
| Stallard Properties Limited | Administrative & support | 2018 |
| Stamford Global Holdings Limited | Financial services | 2026 |
| Stand 2 (Specialist Training and Development) Limited | Professional & scientific | 2005 |
| Stand Firm Foot Care Limited | Health & social care | 2022 |
| Standout Cleaning Ltd | Administrative & support | 2023 |
| Standout Water Ltd | Water & waste | 2026 |
| Stanford Farms (Worcs) Limited | Administrative & support | 2011 |
| Stanford Marsh Group Holdings Limited | Financial services | 2024 |
| Stanford Marsh Limited | Wholesale & retail | 1965 |
| Stanford Park Residents Management Company Limited | Households | 2009 |
| Stanway Steam Ltd | Administrative & support | 2026 |
| Star Building Construction and Management Ltd | Real estate | 2020 |
| Starlight Contract Cleaning Services Limited | Administrative & support | 2021 |
| Starm Global Ltd | Wholesale & retail | 2024 |
| Starpoint Ventures Ltd | Other services | 2025 |
| Start Acdc Limited | Wholesale & retail | 2017 |
| Start Electrical Services Limited | Construction | 2003 |
| Startsector Property Management Limited | Real estate | 1987 |
| Stay Curious PR Ltd | Professional & scientific | 2025 |
| Steady Circuit Ltd | Information & communication | 2025 |
| Steadyclean Ltd | Administrative & support | 2024 |
| Stealth Technologies Ltd | Manufacturing | 2009 |
| Steam Properties Limited | Real estate | 2025 |
| Steer Automotive Group Limited | Wholesale & retail | 2012 |
| Steer Repair Limited | Financial services | 2024 |
| Stefan.Baster Ltd | Transport & logistics | 2011 |
| Stein Model Engineering Limited | Manufacturing | 2015 |
| Stelan & Co Limited | Construction | 2025 |
| Stelr Group Ltd | Wholesale & retail | 2023 |
| Stem Tyres and Services Ltd | Wholesale & retail | 2024 |
| Step by Step Recruitment Limited | Administrative & support | 2008 |
| Step Pro Ltd | Construction | 2025 |
| Stephanie Austwick Ltd | Education | 2015 |
| Stephen Mills Engineering Limited | Construction | 2024 |
| Stephenkelly Limited | Health & social care | 2018 |
| Stepping UP Performing Arts Limited | Education | 2026 |
| Stepway Trading Ltd | Wholesale & retail | 2023 |