| Stoke Poges Properties Ltd | Real estate | 2026 |
| Stone & Sovereign Ltd | Manufacturing | 2026 |
| Stone Developments (AB) Limited | Construction | 2015 |
| Stone Fintech Ltd | Wholesale & retail | 2026 |
| Stone Projects Properties Limited | Real estate | 2026 |
| Stone's Throw Ltd | Information & communication | 2012 |
| Stoneacre Wealth Management Ltd | Financial services | 2019 |
| Stonefeather Holdings Ltd | Professional & scientific | 2025 |
| Stoneleigh Park Residents Management Company Limited | Households | 2001 |
| Stones Throw Holdings Ltd | Financial services | 2026 |
| Stonesfield Development Limited | Construction | 2024 |
| Stoneycroft Property Development Group Limited | Real estate | 2025 |
| Stopford Investments Ltd | Other services | 2023 |
| Stopford Medical Ltd | Health & social care | 2022 |
| Storer Properties Limited | Real estate | 2026 |
| Storestuff Self Storage Ltd | Transport & logistics | 2024 |
| Storeybook Software Limited | Information & communication | 2025 |
| Storm Brain Tech Ltd | Information & communication | 2026 |
| Storm Industrial Roofing Limited | Construction | 2009 |
| Stormguard UK Limited | Wholesale & retail | 2008 |
| Stormproof Roofers Ltd | Construction | 2018 |
| Stormx Tech Solutions Ltd | Information & communication | 2026 |
| Story Saver Ltd | Professional & scientific | 2026 |
| Stourcote Dental Practice Ltd | Health & social care | 2015 |
| Stourcote Property Company Ltd | Real estate | 2014 |
| Stradey Partners Ltd | Other services | 2019 |
| Stradiz Ltd | Wholesale & retail | 2026 |
| Straight Medical Ltd | Health & social care | 2020 |
| Straight UP Drinks Limited | Other services | 1994 |
| Strand Line Studio Ltd | Manufacturing | 2019 |
| Strategic Atlantic Technologies Ltd | Administrative & support | 2023 |
| Strategic Contract Claims Ltd | Professional & scientific | 2022 |
| Strategic Operatives Ltd | Information & communication | 2023 |
| Stratexus Ltd | Professional & scientific | 2026 |
| Stratoscaling Ltd | Wholesale & retail | 2026 |
| Stratus Legal Ltd | Professional & scientific | 2025 |
| Stratwell Business Development Ltd | Professional & scientific | 2025 |
| Strawberry Capital Limited | Administrative & support | 2017 |
| Strawberry Lane Properties Ltd | Professional & scientific | 2018 |
| Strawberry Poppets Nursery School Ltd | Extraterritorial | 2025 |
| STREAM4K Ltd | Information & communication | 2026 |
| Streamers Space Ltd | Wholesale & retail | 2025 |
| Streamgenz Ltd | Wholesale & retail | 2025 |
| Streamline Auto-Beds Limited | Manufacturing | 2014 |
| Streamline Holdings Limited | Administrative & support | 2016 |
| Streetbites Food Limited | Hospitality | 2026 |
| Strength&Endurance Ltd | Health & social care | 2023 |
| Stretton Barber Shop Ltd | Other services | 2023 |
| Strevens Holdings Limited | Financial services | 2025 |
| Strevens Properties Limited | Construction | 2026 |
| Strike OFF 31 December 2029 Limited | Real estate | 1986 |
| Stringthing Limited | Arts & recreation | 2019 |
| Stripefox Limited | Wholesale & retail | 2017 |
| Strive Events UK Ltd | Health & social care | 2020 |
| Stromeferry Holdings Limited | Real estate | 2024 |
| Stronghold Tech Ltd | Information & communication | 2023 |
| Structural Detailing (Midlands) Limited | Other services | 2010 |
| Structural Glazing Limited | Construction | 1991 |
| Strutfast UK Ltd | Wholesale & retail | 2021 |
| STS Empire Ltd | Wholesale & retail | 2025 |
| STS Pubs Limited | Hospitality | 2024 |
| STS Visualz Ltd | Wholesale & retail | 2024 |
| Stuart Hickman Associates Ltd | Professional & scientific | 2015 |
| Stuart Solutions Limited | Education | 2003 |
| Stubby Lane Wines Ltd | Wholesale & retail | 2020 |
| Student Plus Limited | Administrative & support | 2018 |
| Studentcrowd Limited | Information & communication | 2014 |
| Studio 110 Ltd | Other services | 2025 |
| Studio Aurea Ltd | Professional & scientific | 2025 |
| Studio Five Limited | | 1985 |
| Studio Motions Limited | Information & communication | 2013 |
| Studio Severn Architects Limited | Professional & scientific | 2010 |
| STUDIO75WOLVERHAMPTON Ltd | Other services | 2022 |
| Study Vault Ltd | Professional & scientific | 2025 |
| Stumode Limited | Health & social care | 2024 |
| Stump Exit Ltd | Administrative & support | 2024 |
| Stush Haircare Limited | Other services | 2020 |
| Stylebyamanthiara Limited | Other services | 2025 |
| Styleen Ltd | Wholesale & retail | 2021 |
| Stylelite Limited | Professional & scientific | 2017 |
| Stylish Beauty Salon Ltd | Other services | 2015 |
| Stylistic Cleaners Ltd | Administrative & support | 2018 |
| SU Casa Estates Limited | Hospitality | 2017 |
| Su-Uh's Solutions Ltd | Health & social care | 2025 |
| SUB3 Consultancy Limited | Information & communication | 2024 |
| Subedar Limited | Transport & logistics | 2022 |
| Subfactory Ltd | Hospitality | 2026 |
| Subhan Bazaar Ltd | Wholesale & retail | 2026 |
| Subhan Solutions Ltd | Information & communication | 2026 |
| Sublime Care Solution Limited | Health & social care | 2016 |
| Sublime Sports U.K Ltd | Manufacturing | 2020 |
| Subsidium Services Ltd | Administrative & support | 2024 |
| Subsurface Earth Ltd | Professional & scientific | 2022 |
| Succeed Through Speaking Ltd | Education | 2018 |
| Success and Chimamanda Ultrasound Service Limited | Administrative & support | 2019 |
| Success Prime Limited | Administrative & support | 2025 |
| Success With Clear Innovation Limited | Other services | 2016 |
| Successaction Marketing Ltd | Professional & scientific | 2026 |
| Sudan Virtual Medical Academy (Svma) Ltd | Education | 2023 |
| Sudanese Community in Wolverhampton | Other services | 2019 |