| Sarwar Property Rentals Limited | Real estate | 2025 |
| SAS Auto Center Limited | Wholesale & retail | 2024 |
| SAS Chand Ltd | Real estate | 2026 |
| SAS Mechanical & Electrical Ltd | Manufacturing | 2016 |
| SAS8 Ltd | Administrative & support | 2019 |
| Sasco Property Investments Limited | Real estate | 2018 |
| Sasha Software Testing Services Ltd | Information & communication | 2018 |
| Sasie Homes Limited | Real estate | 2020 |
| Saskia Ltd | Professional & scientific | 2024 |
| Sassy Coffee (Shops) Ltd | Hospitality | 2022 |
| Sassy Sensory Surprises CIC | Health & social care | 2023 |
| Sassy's Hair Ltd | Other services | 2014 |
| Sasti Retailers Ltd | Wholesale & retail | 2026 |
| Sastre Services Ltd | Other services | 2023 |
| SAT Sahib Transport Ltd | Transport & logistics | 2021 |
| Sath Guru Builders Ltd | Construction | 2015 |
| Satinaa Abys Ltd | Wholesale & retail | 2025 |
| Satnam K Limited | Construction | 2021 |
| Saturn BODYWORK5 Ltd | Wholesale & retail | 2024 |
| Saturn BOY Recordings Limited | Administrative & support | 2019 |
| Saturn Diner Ltd | Hospitality | 2024 |
| Saturn Entertainment Limited | Administrative & support | 2016 |
| Saturn Innovation Limited | Information & communication | 1999 |
| Saturn Investments Limited | Real estate | 2026 |
| Saulpro Ltd | Construction | 2025 |
| Saunders Trade Logistics Ltd | Transport & logistics | 2024 |
| Saussurea Ltd | Hospitality | 2023 |
| SAV F Construct Ltd | Transport & logistics | 2024 |
| Savage Group Limited | Manufacturing | 2018 |
| Savanna Housing CIC | Hospitality | 2020 |
| Savannah Global Limited | Wholesale & retail | 2025 |
| Save on Bills Ltd | Other services | 2014 |
| Save Seasons Limited | Wholesale & retail | 2024 |
| Savelife Recruitment & Support Services Limited | Administrative & support | 2022 |
| Saveline Supermarket Limited | Wholesale & retail | 2003 |
| Saveoncheckout Ltd | Information & communication | 2026 |
| Savequick Limited | Wholesale & retail | 2025 |
| Saver Express Finchfield Ltd | Wholesale & retail | 2022 |
| Saver Express Local Ltd | Wholesale & retail | 2016 |
| Savesta Build Limited | Construction | 2020 |
| Savesta Construction Ltd | Construction | 2018 |
| Savesta Consult Ltd | Professional & scientific | 2019 |
| Savesta Limited | Construction | 2017 |
| Savewell Limited | Health & social care | 2026 |
| Savita Kitchen Ltd | Other services | 2023 |
| Savitas Hair & Beauty Ltd | Other services | 2022 |
| Saviton Contracts Limited | Wholesale & retail | 2019 |
| Savvy Consulting Group Limited | Administrative & support | 2021 |
| Savvy Marketing, PR and Growth Limited | Administrative & support | 2021 |
| Savvyloft Care Services Limited | Health & social care | 2024 |
| SAY IT With Hands Ltd | Professional & scientific | 2025 |
| Saya Travels Ltd | Administrative & support | 2025 |
| Sayed Trading & Electronics Ltd | Wholesale & retail | 2025 |
| SAZ (JEF) Ltd | Real estate | 2024 |
| SB 4 U Ltd | Hospitality | 2023 |
| SB Automation Ltd | Professional & scientific | 2013 |
| SB Bodenlaw Limited | Hospitality | 2022 |
| SB Cake and Sweets Ltd | Wholesale & retail | 2025 |
| SB Capitol Ltd | Real estate | 2013 |
| SB Medical Services Private Limited | Health & social care | 2012 |
| SB Medics Limited | Administrative & support | 2014 |
| Sbab Properties Ltd | Real estate | 2023 |
| Sbcs Screens Ltd | Wholesale & retail | 2025 |
| Sbgs Construction Limited | Construction | 2025 |
| SBJ Associates Ltd | Construction | 2018 |
| SBK Customs Ltd | Manufacturing | 2020 |
| SBR Building Services Ltd | Construction | 2025 |
| SBS Health Ltd | Wholesale & retail | 2025 |
| SBS International Limited | Wholesale & retail | 1994 |
| SBS Transport and Installation Limited | Transport & logistics | 2024 |
| SBT Hair Limited | Other services | 2020 |
| SBV Healthcare Ltd | Transport & logistics | 2021 |
| SC Marketing Consultants Limited | Professional & scientific | 2010 |
| SC Midlands Ltd | Construction | 2023 |
| SCA Management Consulting Ltd | Professional & scientific | 2010 |
| Scaffold West Midlands Ltd | Construction | 2018 |
| Scaftec Services Ltd | Construction | 2023 |
| Scale Roas BZT Ltd | Professional & scientific | 2026 |
| SCAN2TRAY Ltd | Administrative & support | 2026 |
| Scandic Timber (UK) Limited | Construction | 2009 |
| SCG Estates Ltd | Real estate | 2020 |
| SCH Services (2007) Ltd | Administrative & support | 2024 |
| Schem Services Limited | Administrative & support | 2007 |
| Scholaris Education International Ltd | Education | 2022 |
| Scholars House Limited | Health & social care | 2015 |
| Scholarsphere Consulting Limited | Education | 2025 |
| School of Coding & AI Limited | Information & communication | 2024 |
| School of Coding AEP Limited | Information & communication | 2023 |
| School of Coding Limited | Information & communication | 2017 |
| School of Cyber Security Limited | Extraterritorial | 2023 |
| School of Life Solutions Ltd | Professional & scientific | 2025 |
| Schools First Limited | Administrative & support | 2001 |
| Schools Payroll Ltd | Education | 2019 |
| Schott UK Limited | Wholesale & retail | 1976 |
| Schreuderconsult Ltd | Professional & scientific | 2025 |
| Scienqua Ltd | Professional & scientific | 2023 |
| Scjr Ltd | Information & communication | 2026 |
| SCL Health Limited | Health & social care | 2021 |
| Sconmed Int'L Limited | Health & social care | 2024 |
| Scootly UK Ltd | Wholesale & retail | 2026 |