| ET Ficti Design Ltd | Manufacturing | 2017 |
| ET Learning Solutions Development Limited | Education | 2021 |
| Eternal Celebrations Ltd | Administrative & support | 2023 |
| Etherneco Ltd | Information & communication | 2023 |
| Ethnopsych Ltd | Professional & scientific | 2021 |
| Ethos Packaging Limited | Administrative & support | 2023 |
| Etphd Method Limited | Education | 2022 |
| EU Management Limited | Administrative & support | 2024 |
| Eunoia Ventures Limited | Professional & scientific | 2026 |
| Eurocraft Imports Ltd | Wholesale & retail | 2026 |
| Eurodoor UK Limited | Construction | 1998 |
| Euroleather UK Limited | Administrative & support | 2008 |
| Eurotool Groundwork’S and Civils Ltd | Construction | 2023 |
| EV Plus Limited | Energy | 2020 |
| EVA & FIN Ltd | Wholesale & retail | 2025 |
| Evaerem Ltd | Financial services | 2026 |
| Evans Business Support Limited | Information & communication | 2025 |
| Evans Corporation Limited | Wholesale & retail | 1964 |
| Evans Legal Consultancy Ltd | Professional & scientific | 2022 |
| Evelyn Gardens Property Limited | Real estate | 2023 |
| Evelyn Rose Interiors Ltd | Wholesale & retail | 2025 |
| Evenstate Limited | Information & communication | 2003 |
| Events 471 Limited | Arts & recreation | 2022 |
| Everbright Home Care Ltd | Health & social care | 2018 |
| Everest Radiology Ltd | Health & social care | 2025 |
| Every Lesson Counts Tutoring Limited | Education | 2013 |
| Everydayz Moreton Ltd | Wholesale & retail | 2023 |
| Everything Entertainment Ltd | Administrative & support | 2016 |
| Eveson Medical Limited | Health & social care | 2023 |
| Evipro Ltd | Information & communication | 2022 |
| EVO Management Ltd | Real estate | 2013 |
| EVO Sports Education Limited | Education | 2014 |
| Evohuman Ltd | Professional & scientific | 2025 |
| Evolve + Consultancy Limited | Professional & scientific | 2023 |
| Evolve Cleaner Ltd | Manufacturing | 2026 |
| Evolve-Trans Ltd. | Wholesale & retail | 2019 |
| EW LAB (UK) Limited | Manufacturing | 2025 |
| Ewen Editing Services Ltd | Information & communication | 2019 |
| Eweneek Ltd | Wholesale & retail | 2026 |
| EWJ Properties Ltd | Real estate | 2026 |
| EWS Estates Limited | Real estate | 2024 |
| Excavo Civils Limited | Administrative & support | 2016 |
| Excel Communications Limited | Information & communication | 2022 |
| Excel Scaffolding (North West) Limited | Construction | 2014 |
| Excel-Ace Limited | Information & communication | 2008 |
| Excellence Science Tutoring Ltd | Administrative & support | 2025 |
| Excession Automations Ltd | Information & communication | 2024 |
| Exchange Bar Heswall Limited | Hospitality | 2018 |
| Exclusive Management Ltd | Wholesale & retail | 2025 |
| Execute Hospitality Ltd | Hospitality | 2025 |
| Exhibit World Limited | Administrative & support | 2007 |
| Exile Sportswear Limited | Arts & recreation | 2012 |
| EXIT(0); Digital Limited | Information & communication | 2018 |
| Exmoor Equine Clinic Ltd | Professional & scientific | 2024 |
| EXN Transport Service Ltd | Transport & logistics | 2023 |
| Expand Estate Limited | Professional & scientific | 2023 |
| Expandingdata Ltd | Information & communication | 2026 |
| Experience North Ltd | Administrative & support | 2017 |
| Experience Researchq Ltd | Professional & scientific | 2025 |
| Experimental Rock Mechanics Ltd | Manufacturing | 2011 |
| Expert Property Repairs Wirral Limited | Extraterritorial | 2022 |
| Expert Witness Engagement Gateway Limited | Other services | 2025 |
| Explanatum Ltd | Professional & scientific | 2025 |
| Extension Experts Limited | Construction | 2019 |
| Extensions by JEN Limited | Other services | 2019 |
| Eyal Convenience Ltd | Real estate | 2021 |
| Eyas Cosmetics Limited | Wholesale & retail | 2023 |
| EYE CAB Limited | Wholesale & retail | 2013 |
| EYE SEE Hares Ltd | Information & communication | 2024 |
| Eyedeal Limited | Wholesale & retail | 1991 |
| Ezards Lighting Ltd | Manufacturing | 2001 |
| F R Real Estate Ltd | Real estate | 2018 |
| F.I. Kingsley Ltd | Administrative & support | 2011 |
| F.P. Auto's Body Repairers Limited | Wholesale & retail | 2006 |
| FA2K Ltd | Professional & scientific | 2025 |
| FAB Four Productions Limited | Arts & recreation | 2014 |
| Fabled Vaults Limited | Wholesale & retail | 2025 |
| Fabra Communications Limited | Information & communication | 2011 |
| Facedip Ltd | Wholesale & retail | 2025 |
| Fagami Limited | Wholesale & retail | 2025 |
| Fairbiz Ltd | Wholesale & retail | 2020 |
| Fairway Wirral Limited | Wholesale & retail | 2023 |
| Faith and Embrace Limited | Financial services | 2010 |
| Faith Forward CIC | Health & social care | 2025 |
| Faith Plus Ltd | Wholesale & retail | 2024 |
| Falconsflight Limited | Agriculture & fishing | 2018 |
| Family Advocacy & Childrens Care Services Ltd | Health & social care | 2024 |
| Family Asset Holdings (NW) Ltd | Real estate | 2024 |
| Family Driven Motors Limited | Wholesale & retail | 2024 |
| Family Medical Ltd | Health & social care | 2025 |
| Farebrother Transport Limited | Transport & logistics | 2003 |
| Farmly Foods Limited | Wholesale & retail | 2014 |
| Farnley Investments Limited | Financial services | 2018 |
| Farringdon and Forbes Home Interiors Ltd | Wholesale & retail | 2019 |
| Fashion Deep Ltd | Wholesale & retail | 2025 |
| Fashion Flex Ltd | Wholesale & retail | 2020 |
| Fashion Fortunes Limited | Other services | 2026 |
| Fashion K Ltd | Wholesale & retail | 2022 |
| Fashionandjewels Ltd | Wholesale & retail | 2009 |
| Fast and Female Limited | Education | 2026 |