| RVL Consultants Intl. Ltd | Professional & scientific | 2017 |
| Rvlto Limited | Arts & recreation | 2024 |
| Ryska Limited | Real estate | 2025 |
| Rythm Studio Limited | Professional & scientific | 2026 |
| Ryztech Ltd | Information & communication | 2021 |
| S & S Investments (GBR) Limited | Real estate | 2021 |
| S & S Joinery (Southern) Limited | Manufacturing | 2018 |
| S a New Limited | Professional & scientific | 2025 |
| S C I Systems Ltd | Administrative & support | 2001 |
| S C T & S C T Limited | Wholesale & retail | 2017 |
| S Crompton Solutions Limited | Information & communication | 2025 |
| S D Rudling Ltd | Professional & scientific | 2025 |
| S Danisz Consulting Limited | Professional & scientific | 2018 |
| S E Gibbs Consulting Ltd | Professional & scientific | 2021 |
| S J B Environmental Ltd | Professional & scientific | 2019 |
| S J Barrett Property Investments Limited | Real estate | 2019 |
| S J Holland Holdings Limited | Real estate | 2020 |
| S J Holland Limited | Real estate | 2020 |
| S J Squires Ltd | Information & communication | 2016 |
| S M Cairns Limited | Professional & scientific | 2022 |
| S Nair Investments Limited | Financial services | 2025 |
| S S Shah Consulting Limited | Professional & scientific | 2023 |
| S W Brickwork Limited | Construction | 2003 |
| S&B Carter Holdings Ltd | Real estate | 2025 |
| S&J Food and Drink Ltd | Hospitality | 2021 |
| S&J Investment Properties Ltd | Real estate | 2021 |
| S&J Investments Limited | Real estate | 2018 |
| S&J Ventures Ltd | Wholesale & retail | 2020 |
| S'Oak Artisan Studio Ltd | Arts & recreation | 2026 |
| S. S. J. Consulting Ltd | Financial services | 2015 |
| S.J. Hills Ltd | Construction | 2013 |
| S.M.D. Fixings Limited | Construction | 1998 |
| S.M.Electronics Design Limited | Administrative & support | 2011 |
| S.O.S. Swim School Ltd | Education | 2015 |
| S.Yang Contracting Services Limited | Administrative & support | 2019 |
| S.Zoe Solutions Limited | Information & communication | 2017 |
| S29 Consultancy Limited | Professional & scientific | 2023 |
| S2S Global Ltd | Professional & scientific | 2019 |
| SA Startup Consulting Ltd | Professional & scientific | 2022 |
| SA Stat Limited | Professional & scientific | 2014 |
| Sabre Architectural Metalwork Ltd | Construction | 2017 |
| Sabtel Consulting Limited | Information & communication | 2022 |
| Safe Pixel Consultancy Limited | Information & communication | 2025 |
| SAFE2SURF Limited | Professional & scientific | 2002 |
| Safeguard Security Consultants Limited | Administrative & support | 1988 |
| Safehands Football Consultancy Ltd | Professional & scientific | 2023 |
| Safehigher Limited | Extraterritorial | 2004 |
| Safepoint Building Services Ltd. | Construction | 2012 |
| Safor Consultants Limited | Information & communication | 2021 |
| Sagac Limited | Professional & scientific | 2015 |
| Sage Solutions Consulting Limited | Professional & scientific | 2023 |
| Saibatech Solutions Limited | Information & communication | 2025 |
| Saiganesh Consulting Limited | Professional & scientific | 2025 |
| Sailfish Limited | Professional & scientific | 2008 |
| SAL Scientific Limited | Professional & scientific | 2013 |
| Salamander Shirts Ltd | Wholesale & retail | 2019 |
| Salisbury Optical Ltd | Health & social care | 2022 |
| Salt Craft Studios Ltd | Information & communication | 2024 |
| Salts Direct Limited | Wholesale & retail | 2017 |
| Salvya Enterprises Limited | Financial services | 2025 |
| Salvyn Limited | Information & communication | 2011 |
| Samaria Investments Limited | Real estate | 2024 |
| Sambid Consulting Limited | Professional & scientific | 2021 |
| Same Homes Ltd | Construction | 2015 |
| Samson Motorsport Limited | Financial services | 2021 |
| Samson Self Storage Ltd | Transport & logistics | 2024 |
| SAN Pedro Software Limited | Information & communication | 2025 |
| Sanam Technology Limited | Professional & scientific | 2020 |
| Sandbanks Collective Ltd | Administrative & support | 2026 |
| Sandbanks Formwork Limited | Construction | 2006 |
| Sander Solutions Limited | Professional & scientific | 2023 |
| Sanders Civil & Rail Engineering Limited | Other services | 2013 |
| Sandford ST. Martins Nursery School CIC | Education | 2013 |
| Sandgrown Software Ltd | Information & communication | 2021 |
| Sandhu Solutions Ltd | Information & communication | 2018 |
| Saner Consulting Ltd | Professional & scientific | 2016 |
| Sangrila Coffee Ltd | Hospitality | 2024 |
| Santori IP Ltd | Administrative & support | 2026 |
| Santori PMC Ltd | Other services | 2024 |
| Santori UK Group Holdings Ltd | Financial services | 2026 |
| Santoy Freehold Limited | Households | 2018 |
| Sapenta Analytics Ltd | Information & communication | 2023 |
| Sara Gordon Limited | Extraterritorial | 2009 |
| Sarah & Sarah Interiors Limited | Professional & scientific | 2021 |
| Sarah Greaves Stem Consulting Ltd | Professional & scientific | 2022 |
| Sarum RE Ltd | Real estate | 2020 |
| Satellite Aerials Security Ltd | Information & communication | 2017 |
| Satnam Consulting Ltd | Information & communication | 2015 |
| Saturnxli Limited | Information & communication | 2023 |
| Saucisson Limited | Professional & scientific | 2024 |
| Sausage Dog Box Ltd | Wholesale & retail | 2020 |
| Savy Property Management Limited | Real estate | 2019 |
| Saxondale Gardens Management Company Ltd | Households | 2023 |
| Saxtead Solutions Limited | Information & communication | 2020 |
| Sayed Catering Limited | Hospitality | 2015 |
| Sayers Consulting Ltd | Information & communication | 2013 |
| SAZ & Milly Ltd | Real estate | 2025 |
| SBC Accounts Limited | Professional & scientific | 2020 |
| SCA Services Ltd | Professional & scientific | 2025 |
| Scea Limited | Administrative & support | 2019 |