| ECS Software Consulting Ltd. | Information & communication | 2016 |
| ED Burrell Films Limited | Information & communication | 2019 |
| Eden Store Ltd | Wholesale & retail | 2016 |
| Edgenet Industrial Ltd | Construction | 2024 |
| EDI Solutions Ltd | Information & communication | 2012 |
| Edina Homes Limited | Real estate | 2024 |
| Edmondson Aviation Limited | Administrative & support | 2010 |
| Edms Accounts Limited | Professional & scientific | 2025 |
| Edroff Ltd | Financial services | 2016 |
| Eds&Tails Ltd | Extraterritorial | 2023 |
| Edward Holdings (UK) Ltd | Financial services | 2013 |
| Edward Lettings Ltd | Real estate | 2012 |
| Edward Properties (Southern) Limited | Real estate | 2020 |
| Edwin Campbell Consulting Limited | Mining & quarrying | 2022 |
| EF Project Management Limited | Information & communication | 2020 |
| Effective Solutions Kent Ltd | Professional & scientific | 2018 |
| Effiwind Limited | Professional & scientific | 2018 |
| EH Wash 'N' DRY Ltd | Other services | 2015 |
| Eica Solutions Limited | Construction | 2022 |
| Eidesvik UK Limited | Professional & scientific | 2016 |
| EIGHT4TWO Music Consultancy and Management Limited | Administrative & support | 2022 |
| Eighteena Limited | Hospitality | 2023 |
| Eilean Services Limited | Information & communication | 2020 |
| Einsichtly Consulting Limited | Professional & scientific | 2025 |
| EIS Club Ltd | Professional & scientific | 2023 |
| EJB Automation Limited | Professional & scientific | 2023 |
| EJG Software Ltd | Information & communication | 2021 |
| EKK Consultancy Services Limited | Information & communication | 2014 |
| Ekon Ltd | Wholesale & retail | 2019 |
| EKZ Ltd | Information & communication | 2026 |
| Elantis Solutions (UK) Limited | Information & communication | 2023 |
| Eldia Consulting Ltd | Information & communication | 2022 |
| Electric Badger Ltd | Information & communication | 2022 |
| Electrical Technician Solutions Limited | Manufacturing | 2025 |
| Electronic Technicians Holdings Limited | Extraterritorial | 2019 |
| Electronic Technicians Limited | Manufacturing | 1981 |
| Elegantia IT Services Limited | Information & communication | 2026 |
| Elektron Media Ltd | Information & communication | 2022 |
| Elevare Consulting Ltd | Professional & scientific | 2024 |
| Elevate Itsm Limited | Information & communication | 2021 |
| Elevated Insights Limited | Professional & scientific | 2025 |
| Eleven Trees Ltd | Administrative & support | 2022 |
| Eleventh Hour Publishing Limited | Professional & scientific | 2012 |
| ELF Limited | Wholesale & retail | 1993 |
| Elgarwood Construction Ltd | Construction | 2020 |
| Elgin White Limited | Administrative & support | 2006 |
| Eling Construction (Southern) Limited | Extraterritorial | 2004 |
| Elite Cabs Dorset Limited | Transport & logistics | 2024 |
| Elite Cyber Security Force Ltd | Information & communication | 2025 |
| Elite Leadership Solutions Ltd | Professional & scientific | 2024 |
| Elitech Solutions Ltd | Information & communication | 2017 |
| Ella Starbuck Consultancy Ltd | Professional & scientific | 2026 |
| Ellam Consulting Limited | Information & communication | 2011 |
| Ellard Consulting Ltd | Professional & scientific | 2017 |
| Ellazak Ltd | Financial services | 2020 |
| Ellfords Accident & Repair Centre Limited | Wholesale & retail | 1995 |
| Elliott Architecture Limited | Professional & scientific | 2024 |
| Elliott-Rogers Build Co Ltd | Construction | 2026 |
| Elliotts (UK) Auctioneers & Valuers Limited | Wholesale & retail | 2003 |
| ELM Homes Limited | Real estate | 2020 |
| Elmar Commercial Services Limited | Professional & scientific | 1980 |
| Elos Industries Limited | Other services | 2005 |
| Elves and Fairies Ltd | Health & social care | 2025 |
| Elyseum Ltd | Other services | 2017 |
| EM Trade Solutions Ltd | Wholesale & retail | 2025 |
| Ember Change Consulting Limited | Professional & scientific | 2015 |
| Ember Logic Limited | Information & communication | 2026 |
| Embr Innovation Ventures Ltd | Professional & scientific | 2024 |
| Embrace Travel Group Ltd | Other services | 2021 |
| Embrace Yoga Studio Ltd | Other services | 2026 |
| Emdee Comms Ltd | Information & communication | 2018 |
| Emera Consulting Limited | Professional & scientific | 2022 |
| Emerald Cards Limited | Wholesale & retail | 2023 |
| Emerald Clothing Limited | Wholesale & retail | 2023 |
| Emerald HR Consulting Ltd | Professional & scientific | 2019 |
| Emerson Cook Consulting Ltd | Information & communication | 2018 |
| Emily Marshall Photography Ltd | Professional & scientific | 2025 |
| Emily’S Wardrobe Limited | Wholesale & retail | 2017 |
| Eminent Property Limited | Real estate | 2017 |
| Emirates Financial Consulting Limited | Information & communication | 2013 |
| Emma Clarke PR Limited | Professional & scientific | 2021 |
| Emma Hackett Coaching & Consulting Ltd | Professional & scientific | 2026 |
| Emmers Farm Limited | Real estate | 2020 |
| Empowersportsmanagement Limited | Arts & recreation | 2021 |
| Empr Services Limited | Construction | 2018 |
| Emptor Associates Limited | Professional & scientific | 2022 |
| Empyrea Analytics Ltd | Professional & scientific | 2025 |
| EMU Analytics Limited | Information & communication | 2014 |
| EMU Data Products Limited | Extraterritorial | 2015 |
| Enable Technical Solutions Limited | Professional & scientific | 2022 |
| Enable Today Ltd | Health & social care | 2016 |
| Enablely Limited | Information & communication | 2025 |
| Encompass Telecom Limited | Wholesale & retail | 2003 |
| END 2 END Engineering Ltd | Professional & scientific | 2021 |
| Endless Solutions (UK) Limited | Information & communication | 1999 |
| Endorset Events Ltd | Arts & recreation | 2022 |
| Energise Commercial Ltd | Financial services | 2026 |
| Energise Finance Group Ltd | Financial services | 2026 |
| Energise Financial Ltd | Extraterritorial | 2026 |
| Energise Mortgages Ltd | Financial services | 2026 |