| Roy's Roofing and Driveways Limited | Construction | 2023 |
| RPS Management Midlands Ltd | Real estate | 2022 |
| RRI UK (Training and Consultancy) Limited | Education | 2024 |
| RRR Transport Ltd | Transport & logistics | 2024 |
| RS Detailing Ltd | Wholesale & retail | 2024 |
| RS Guhman Enterprises Ltd | Health & social care | 2015 |
| RS Rider Limited | Transport & logistics | 2022 |
| RSA Electrical Solutions Ltd | Construction | 2025 |
| RSJ Motors Ltd | Wholesale & retail | 2011 |
| RSO Developments Ltd | Manufacturing | 2018 |
| RSP Contracts Ltd | Construction | 2018 |
| RTA Global Ltd | Manufacturing | 2014 |
| RTH & Sons Ltd | Wholesale & retail | 2025 |
| Ruach Creations Ltd | Professional & scientific | 2023 |
| Rubab Golden FRY Ltd | Hospitality | 2026 |
| Ruhukwa Ltd | Health & social care | 2021 |
| Rukhsana Munir Limited | Real estate | 2019 |
| Runaway Bay Ltd | Hospitality | 2018 |
| Rurk Limited | Hospitality | 2026 |
| RW Property Ventures Ltd | Real estate | 2023 |
| RY Holdings Ltd | Real estate | 2024 |
| RZ Group Ltd | Real estate | 2024 |
| RZ Immigration Ltd | Professional & scientific | 2025 |
| S a Prime Estates Limited | Construction | 2024 |
| S Aucott Limited | Hospitality | 2023 |
| S C R Drive Limited | Transport & logistics | 2017 |
| S D P Cleaning Limited | Administrative & support | 2017 |
| S D Roofing & Loft Conversion Ltd | Construction | 2019 |
| S F Bolting Ltd | Professional & scientific | 2025 |
| S Homes Midlands Ltd | Real estate | 2023 |
| S J Auto Parts Limited | Wholesale & retail | 2025 |
| S M Uppal Ltd | Transport & logistics | 2024 |
| S Such Enterprises Limited | Hospitality | 2020 |
| S V Productions Ltd | Information & communication | 2015 |
| S&J Driver Recruitment Limited | Administrative & support | 2016 |
| S&K Property Group Ltd | Real estate | 2026 |
| S. B. Steels Limited | Manufacturing | 1999 |
| S.K Kang Builders Ltd | Construction | 2018 |
| Saab Business Services Limited | Professional & scientific | 2017 |
| SAB Textiles Limited | Wholesale & retail | 2009 |
| Sadat Freight Ltd | Transport & logistics | 2019 |
| Saddles (Silhouette) Limited | Manufacturing | 2014 |
| Sadha Video Ltd | Information & communication | 2015 |
| Safety Services Direct Limited | Construction | 2004 |
| Safewater Environmental Ltd | Other services | 2006 |
| Sahi Midlands Transport Ltd | Transport & logistics | 2021 |
| Sahib Enterprise Ltd | Transport & logistics | 2025 |
| Saini House Ltd | Real estate | 2025 |
| Sally Pepper Consulting Limited | Professional & scientific | 2017 |
| Salvage Specialist Ltd | Wholesale & retail | 2025 |
| Sam's Fish Bar (WM) Limited | Construction | 2024 |
| Sam's Fish Bar Ltd | Hospitality | 2022 |
| Samson Cloud Support Limited | Information & communication | 2016 |
| Samson Electronics Limited | Wholesale & retail | 2017 |
| SAN Cargo Ltd | Wholesale & retail | 2026 |
| Sandalwood Education Ltd | Education | 2026 |
| Sandbeds Road Residents' Association Limited | Households | 1995 |
| Sanders Holdings Limited | Financial services | 2015 |
| Sanders Mortgage Solutions Limited | Administrative & support | 2016 |
| Sandher-Immigration Ltd | Professional & scientific | 2026 |
| Sandhi Consultancy Ltd | Information & communication | 2013 |
| Sandhu Property (Willenhall) Ltd | Real estate | 2024 |
| Sandhu Transportation Limited | Transport & logistics | 2024 |
| Sandra Paul Associates Ltd | Administrative & support | 2015 |
| Sandwell Alarms Limited | Wholesale & retail | 2001 |
| Sangjaz Ltd | Households | 2025 |
| Sanifix Limited | Other services | 2010 |
| Sans Capital Ltd | Real estate | 2026 |
| Sans Security Ltd | Administrative & support | 2025 |
| Sans Training Group Ltd | Education | 2026 |
| Sant Transport Ltd | Transport & logistics | 2019 |
| SAP IT Services (UK) Limited | Information & communication | 2016 |
| Sapphire Tool & Design Limited | Manufacturing | 2001 |
| Sarah Davis Ltd | Health & social care | 2020 |
| Sarai Building & Construction Ltd | Construction | 2023 |
| Sarai Transport Ltd | Transport & logistics | 2018 |
| Saru Chippy & Restaurant Bar Ltd | Hospitality | 2025 |
| SAT Sahib Services Limited | Transport & logistics | 2021 |
| Save App Group Limited | Information & communication | 2020 |
| SAY Souvlaki Ltd | Hospitality | 2017 |
| SBC & UK Ltd | Construction | 2021 |
| Sbhandal Smiles Limited | Health & social care | 2024 |
| SBK1 Property Ltd | Real estate | 2025 |
| SBS Haulage Limited | Transport & logistics | 2020 |
| Scrap Car Willenhall Limited | Wholesale & retail | 2024 |
| SD Electrical Installations Ltd | Construction | 2023 |
| SDA Laser Ltd | Manufacturing | 2025 |
| SDL Properties and Refurbishments Ltd | Real estate | 2021 |
| Seaside and More Ltd | Wholesale & retail | 2015 |
| Sedab Ltd | Real estate | 2022 |
| Sedana Trading Ltd | Wholesale & retail | 2018 |
| Sehmbi Co Ltd | Construction | 2019 |
| Self Adhesive Specialities Limited | Wholesale & retail | 1986 |
| Seline Beauty Limited | Other services | 2024 |
| Senbrook Education Ltd | Education | 2026 |
| Senior Architectural Systems Limited | Wholesale & retail | 2000 |
| Septime Limited | Transport & logistics | 2019 |
| Serene & Klean Ltd | Administrative & support | 2025 |
| Serene Success Solutions Ltd | Professional & scientific | 2025 |
| Serenity Radiance Limited | Other services | 2026 |