| Every Generation Limited | Other services | 2005 |
| Everyday Lessons CIC | Education | 2025 |
| Everything Agile Limited | Administrative & support | 2013 |
| Everything Platters Ltd | Hospitality | 2023 |
| Evest Limited | Professional & scientific | 2012 |
| Evewood Ltd | Administrative & support | 2014 |
| Evian Investments Limited | Households | 2012 |
| Evidens Consultancy Limited | Information & communication | 2018 |
| Evierosehomes Ltd | Real estate | 2025 |
| EVL Construction Ltd | Construction | 2025 |
| Evoledyne | Professional & scientific | 2023 |
| Evoltra Ltd | Wholesale & retail | 2025 |
| Evolute CLO Ltd | Wholesale & retail | 2023 |
| Evolution Aqua Group Ltd | Financial services | 2022 |
| Evolution Aqua Limited | Manufacturing | 2001 |
| Evolution TCS Ltd | Wholesale & retail | 2023 |
| Evolve B G Holdings Limited | Financial services | 2024 |
| Evolve B G Limited | Professional & scientific | 2005 |
| Evolve Business Management Ltd | Extraterritorial | 2020 |
| Evolve Inclusive Ltd | Education | 2015 |
| Evolvement Group Ltd | Construction | 2022 |
| Evolvement Property Ltd | Real estate | 2022 |
| Evotex Solutions Limited | Information & communication | 2013 |
| EVY Infrastructure Partners Limited | Financial services | 2019 |
| Ewadebola Ltd | Health & social care | 2018 |
| Ewood Retail Limited | Wholesale & retail | 2024 |
| Excalibur Security Limited | Wholesale & retail | 2002 |
| Excellent Gourmet Trading Ltd | Manufacturing | 2014 |
| Exchange Boulevard Ltd | Wholesale & retail | 2024 |
| Exito Group Holdings Ltd | Professional & scientific | 2017 |
| Exito Management Ltd | Financial services | 2018 |
| Exmolink | Professional & scientific | 2023 |
| Exon Retail Ltd | Wholesale & retail | 2024 |
| Exordial Partners Ltd | Professional & scientific | 2023 |
| Expand Limited | Other services | 2003 |
| Expert Content Services Ltd | Professional & scientific | 2024 |
| Expert Fire and Security Ltd | Construction | 2014 |
| Expert Psychiatry Limited | Health & social care | 2013 |
| Expert Roofing and Guttering Ltd | Construction | 2013 |
| Explicit Healthcare Ltd | Health & social care | 2023 |
| Explore Therapeutic Care Services Ltd | Health & social care | 2023 |
| Expol Security and Support Services Limited | Administrative & support | 2013 |
| Express Bingo (Discount) Co. Limited | Manufacturing | 1968 |
| Express Electrical Distributors Limited | Wholesale & retail | 2010 |
| Express Mortgage Services Limited | Financial services | 2004 |
| Express@Fmlogistics Limited | Transport & logistics | 2025 |
| Expresshub Ltd | Wholesale & retail | 2025 |
| Expressions of Beauty Limited | Other services | 2002 |
| Extra Time FC Ltd | Education | 2025 |
| Extreme Abseiling Ltd | Construction | 2014 |
| Ey-Up Wigan CIC | Arts & recreation | 2025 |
| Eyautos Ltd | Wholesale & retail | 2025 |
| Eyemagix Ltd | Other services | 2011 |
| Eyezeon Technologies Ltd | Information & communication | 2015 |
| Eyre Industries Limited | Manufacturing | 2015 |
| F & B Energy Ltd | Construction | 2022 |
| F and S Wigan Ltd | Hospitality | 2025 |
| F B W Engineering Services Limited | Professional & scientific | 1994 |
| F Kasa Ltd | Hospitality | 2024 |
| F Kidwai Ltd | Health & social care | 2024 |
| F&F Rentals Limited | Real estate | 2022 |
| F.C.F. Limited | Professional & scientific | 1999 |
| Fabreco Ltd | Construction | 2013 |
| FAE Capital Limited | Financial services | 2025 |
| Faifar Limited | Construction | 2025 |
| Fair Legal Limited | Administrative & support | 2010 |
| Fairclough Electrical Ltd | Construction | 2019 |
| Fairconnect Ltd | Professional & scientific | 2024 |
| Fairhurst Accountants Ltd | Professional & scientific | 2022 |
| Fairhurst Audit Services Ltd | Professional & scientific | 2023 |
| Fairhurst Joinery Ltd | Construction | 2019 |
| Fairhurst Property Services Ltd | Real estate | 2024 |
| Fairlawn Developments (UK) Limited | Construction | 2007 |
| Fairpave Limited | Construction | 2003 |
| Fairplay Media Ltd | Wholesale & retail | 2023 |
| Fairway Clearance and Harbour Services Limited | Water & waste | 2006 |
| Fairway Rider G3 Limited | Wholesale & retail | 2010 |
| Fairways Property Development Ltd | Real estate | 2025 |
| Fairy Glen Management Company Limited | Households | 2021 |
| Fairy Nails Wigan Ltd | Other services | 2025 |
| Fairyglenn Ltd | Administrative & support | 2024 |
| Faith Boutique Limited | Wholesale & retail | 2020 |
| Faith Hairloss Ltd | Other services | 2017 |
| Faith Luxury Ltd | Other services | 2021 |
| Falcor Trading Limited | Wholesale & retail | 2025 |
| Faleco Limited | Wholesale & retail | 2025 |
| Fall PAC Hire Limited | Professional & scientific | 2009 |
| FAM Technologies Limited | Information & communication | 2019 |
| Familiar Films Ltd | Information & communication | 2019 |
| Family Church | Other services | 1984 |
| Family Martial Arts Centres Ltd | Arts & recreation | 2007 |
| Family Pride Ltd | Administrative & support | 2012 |
| Familykind CIC | Health & social care | 2020 |
| Famlight Energy Ltd | Other services | 2023 |
| FAO Accountancy Services Ltd | Professional & scientific | 2018 |
| Faraysarah Ltd | Health & social care | 2014 |
| Fares Solution Limited | Administrative & support | 2025 |
| Farington Square Ltd | Construction | 2022 |
| Farley Holdings Ltd | Real estate | 2025 |
| Farm House Kitchen Ltd. | Hospitality | 2017 |