| EMR Properties Limited | Hospitality | 1999 |
| Emro Wholesale Ltd | Wholesale & retail | 2021 |
| EMS Asset Management Limited | Water & waste | 2009 |
| Emzy Ltd | Hospitality | 2017 |
| EN VIP Barber Ltd | Other services | 2019 |
| Enable Growth Ltd | Education | 2022 |
| Encams Enterprises Limited | Education | 1995 |
| Encoheal | Professional & scientific | 2023 |
| END of Days Events Ltd | Arts & recreation | 2014 |
| Endabuse CIC | Health & social care | 2019 |
| Endurance Conservatory & Construction Solutions UK Ltd | Construction | 2025 |
| Enforcer Decoys Limited | Wholesale & retail | 2016 |
| Engage 2 Reconnect Wellbeing Ltd | Health & social care | 2024 |
| Engage D&T Limited | Construction | 2014 |
| Engine Room Wigan Ltd | Arts & recreation | 2018 |
| Engineering Matters Limited | Professional & scientific | 2010 |
| Engiplan LLP | | 2026 |
| England’S North Limited | Professional & scientific | 2021 |
| Engraving HQ Ltd | Manufacturing | 2025 |
| Enhanced Electrical & Security Ltd | Construction | 2017 |
| Enigma INT Ltd | Wholesale & retail | 2020 |
| Enigma Performance Centre Ltd | Arts & recreation | 2026 |
| ENJ Words & Media Ltd | Professional & scientific | 2023 |
| Enjones | Professional & scientific | 2023 |
| Enny Stores Ltd | Wholesale & retail | 2024 |
| Enough AS I AM Limited | Health & social care | 2022 |
| Enrichment Travel Ltd | Administrative & support | 2025 |
| Ensembl Ltd | Information & communication | 2025 |
| Enterprise Lighting Ltd | Manufacturing | 2023 |
| Entlix Limited | Information & communication | 2022 |
| Entracare Limited | Education | 2020 |
| Entwicklungswerkstatt Ltd | Professional & scientific | 2022 |
| Entwistle & Joynt Holdings Limited | Wholesale & retail | 2012 |
| ENV Graphics & Signage Limited | Manufacturing | 2015 |
| Enviro-Roof Flat Roofing Systems Limited | Construction | 2004 |
| Envirocleen Limited | Other services | 2009 |
| Enzy Holding Limited | Real estate | 2023 |
| EOS Networks Limited | Professional & scientific | 2015 |
| EPC Ventures Ltd | Information & communication | 2025 |
| EPD Couriers Ltd | Transport & logistics | 2025 |
| EPG Business Limited | Professional & scientific | 2013 |
| EPG Corporate Limited | Professional & scientific | 2013 |
| Ephrata Community Church of Leigh CIC | Health & social care | 2023 |
| Epic Hope CIC | Health & social care | 2023 |
| Epoxy Coat Ltd | Construction | 2018 |
| Epoxy Coating (NW) Ltd | Construction | 2018 |
| Epoxy Resin Floors North West Ltd | Construction | 2023 |
| Equiease Limited | Agriculture & fishing | 2024 |
| Equine Escape CIC | Education | 2022 |
| Equine Shiatsu Therapy Limited | Other services | 2023 |
| Equinvestments Ltd | Professional & scientific | 2023 |
| Equipt Security Group Limited | Administrative & support | 2017 |
| Equitable Derivatives Limited | Professional & scientific | 2008 |
| ERB Developments Limited | Construction | 2017 |
| ERG Property Ltd | Households | 2023 |
| Erimdzius Ltd | Professional & scientific | 2023 |
| Erisio Limited | Wholesale & retail | 2019 |
| Ermaca | Professional & scientific | 2026 |
| ERU Electrical and Security Products Ltd | Wholesale & retail | 2018 |
| ERX Consulting Ltd | Information & communication | 2015 |
| Escape Brewery PUB Co Limited | Hospitality | 2023 |
| Esem Group Ltd | Wholesale & retail | 2018 |
| Eshopping Deals Limited | Wholesale & retail | 2021 |
| Esin Capital Ltd | Real estate | 2022 |
| Espano Grill and Pizza Ltd | Hospitality | 2026 |
| Espen Consultancy Ltd | Professional & scientific | 2024 |
| Essential Components Ltd | Professional & scientific | 2022 |
| Essential Homecare Ltd | Financial services | 2020 |
| Essential People Solutions Limited | Administrative & support | 2008 |
| Essential Safeguarding Limited | Health & social care | 2008 |
| Essomenic Limited | Real estate | 2014 |
| Essomenic Properties Limited | Real estate | 2018 |
| Estate Assist Ltd | Financial services | 2022 |
| Estate of the House of Abbas Ltd | Transport & logistics | 2019 |
| Estate Research Limited | Other services | 2013 |
| Estate Research PC Limited | Other services | 2016 |
| Estate Solutions & Properties Ltd | Construction | 2021 |
| Estatedraw Trading Limited | Professional & scientific | 1994 |
| Etab Autos Limited | Wholesale & retail | 2009 |
| Etch & CUT Laser Ltd | Manufacturing | 2014 |
| ETM OLE Solutions Ltd | Construction | 2014 |
| Eton Way Ltd | Real estate | 2025 |
| Etrademart Ltd | Wholesale & retail | 2023 |
| Euphoria ENT Ltd | Arts & recreation | 2022 |
| Euro Convenience Shop Ltd | Wholesale & retail | 2023 |
| European Auto Recyclers Ltd | Wholesale & retail | 1998 |
| European Diesel Services Limited | Wholesale & retail | 1994 |
| European Linen Supplies Limited | Wholesale & retail | 2021 |
| European Trading Wholesale Limited | Wholesale & retail | 2025 |
| European Tubes Group Limited | Administrative & support | 2016 |
| European Tubes Limited | Wholesale & retail | 1988 |
| Eurostance Ltd | Information & communication | 2022 |
| Eutopia Events Ltd | Arts & recreation | 2025 |
| Euzel | Professional & scientific | 2023 |
| EVA Rose Bathrooms Ltd | Wholesale & retail | 2025 |
| Evantrex | Professional & scientific | 2026 |
| Event Holdings Limited | Hospitality | 2016 |
| Events Catering Installations Limited | Professional & scientific | 2005 |
| Evergreen Wealth Advisors Ltd | Professional & scientific | 2024 |
| Eversure Trades Limited | Construction | 2015 |