| Chida Kitchen and Bar Ltd | Hospitality | 2023 |
| Chris Noble Ltd | Wholesale & retail | 2002 |
| Church Street Local Limited | Wholesale & retail | 2026 |
| Church Street VS Ltd | Wholesale & retail | 2025 |
| CJC Weldability Limited | Construction | 2007 |
| CJS Auto Services Ltd | Wholesale & retail | 2018 |
| Clara's Shop Limited | Wholesale & retail | 2010 |
| Cleaner & Greener Limited | Hospitality | 2023 |
| Cleaner and Greener Domestic Ltd | Administrative & support | 2025 |
| Cleaning Krew Northallerton Limited | Administrative & support | 2024 |
| Clear Reflections Windows Ltd | Administrative & support | 2021 |
| Cleveland Homes Limited | Real estate | 2020 |
| CLG Insulation Limited | Construction | 2022 |
| Clipper Homes Limited | Real estate | 2003 |
| Clive Davies Installations Ltd | Construction | 2021 |
| Clive Davies Limited | Other services | 2003 |
| CME Projects Ltd | Education | 2002 |
| Coast & Camplight Ltd | Hospitality | 2019 |
| Coastal and Country Coaches Limited | Transport & logistics | 1947 |
| Coastal and Country Holiday Properties Ltd | Administrative & support | 2016 |
| Colebrooke Productions Ltd | Arts & recreation | 2024 |
| Coleman Rentals Ltd | Real estate | 2023 |
| Coliseum Trading Company Ltd. | Manufacturing | 1999 |
| Common Cause Community Interest Company | Hospitality | 1989 |
| Congrave Farm Holidays Limited | Hospitality | 2023 |
| Contract Plumbing and Heating Ltd | Construction | 2007 |
| Cornforth Care Ltd | Health & social care | 2018 |
| Cosi Build Ltd | Construction | 2016 |
| Cosi Property (Chesterfield) Ltd | Real estate | 2022 |
| Count on US Cleaning Services Limited | Administrative & support | 2021 |
| Country Cars (Whitby) Limited | Transport & logistics | 2021 |
| Cowen Windows Limited | Manufacturing | 1988 |
| CPA Tree Surgery Ltd | Agriculture & fishing | 2022 |
| Crafty Cove Whitby Ltd | Wholesale & retail | 2020 |
| Crescent School of Motoring Limited | Education | 1991 |
| Critchley Management Company Limited | Households | 2010 |
| CRL Gynaecology Ltd | Professional & scientific | 2020 |
| CRL Medicolegal Ltd | Professional & scientific | 2019 |
| Croft Castings Limited | Manufacturing | 2003 |
| CT-01-PGRN-16183333-PARTNERSHIP Ltd | Hospitality | 2019 |
| CT-02-PGRN-18163333-PARTNERSHIP Ltd | Hospitality | 2019 |
| CT-03-PGRN-17173333-PARTNERSHIP Ltd | Hospitality | 2019 |
| CT-04-PGRN-15193333-PARTNERSHIP Ltd | Hospitality | 2019 |
| CT-05-PGRN-19153333-PARTNERSHIP Ltd | Hospitality | 2019 |
| CT-06-PGRN-20143333-PARTNERSHIP Ltd | Hospitality | 2019 |
| Cupertino Ltd | Real estate | 2022 |
| D. Andrews Glass Ltd | Construction | 2002 |
| D.S and S Thompson Ltd | Construction | 2000 |
| Dale END Services Limited | Administrative & support | 2025 |
| DAN Hogarth Engineering Limited | Professional & scientific | 2025 |
| Danby Bakery Limited | Manufacturing | 2019 |
| Danny Hart Racing Limited | Arts & recreation | 2012 |
| Darling Hair Limited | Other services | 2024 |
| Darlingtons Finest Ltd | Hospitality | 2024 |
| Darren Dobson Joinery Limited | Construction | 2003 |
| David Archer Limited | Construction | 2018 |
| David Close Limited | Construction | 2002 |
| David Neil Crabtree Ltd | Education | 2018 |
| David Shaw Fencing & Forestry Ltd | Construction | 2011 |
| Davies Technical Services Limited | Professional & scientific | 2012 |
| DB Building Ltd | Construction | 2007 |
| Dean Hall Minerals Ltd | Mining & quarrying | 2012 |
| DEB Fletcher Limited | Hospitality | 2012 |
| Decadent Drawing CIC | Arts & recreation | 2019 |
| Deer Stalker Developments Ltd | Construction | 2022 |
| Deli John Leisure Limited | Hospitality | 2022 |
| Demrahh Play Ltd | Arts & recreation | 2013 |
| Dennis Crooks Ltd | Wholesale & retail | 2021 |
| Dependant Solutions Ltd | Information & communication | 2018 |
| Derek Atkinson Limited | Hospitality | 2014 |
| Derek Simpson Ltd | Manufacturing | 2002 |
| Deta BG International Limited | Wholesale & retail | 2010 |
| Diamond Property Renovations Limited | Construction | 2001 |
| Dinosaur & Fossil Shop RHB Ltd | Wholesale & retail | 2024 |
| Discovery Accommodation Limited | Real estate | 2003 |
| Dixon & Huckerby Developments Limited | Real estate | 2012 |
| DJ Properties (Whitby) Ltd | Construction | 2019 |
| DJM Healthcare Consultancy Ltd | Health & social care | 2015 |
| DJW Jewellery Ltd | Wholesale & retail | 2024 |
| Dogwood Productions C.I.C. | Information & communication | 1990 |
| DON Walker Plumbing and Heating Ltd | Construction | 2014 |
| Dowson Group Holdings Ltd | Financial services | 2026 |
| Dowson Property Group Ltd | Real estate | 2026 |
| DR Glasby Medicals Ltd | Health & social care | 2014 |
| DRAGON64 Limited | Professional & scientific | 2012 |
| Drapers Carpets (Whitby) Ltd | Wholesale & retail | 2021 |
| DS Hart Ltd | Real estate | 2024 |
| DSL Services Ltd | Mining & quarrying | 2016 |
| Dualmech Ltd | Construction | 2009 |
| Duck & Bedlington Trading Company Ltd | Wholesale & retail | 2025 |
| Dunwell Homes Ltd | Real estate | 2023 |
| Dynamic Data Services Limited | Information & communication | 2017 |
| Dynamic Retail Systems Ltd | Real estate | 2002 |
| E-Cigs (Guisborough) Ltd | Wholesale & retail | 2015 |
| E.Botham & Sons Limited | Manufacturing | 1972 |
| Easington Mechanical Services Limited | Professional & scientific | 2003 |
| ECB Training Academy Limited | Education | 2024 |
| Edward G. Astin & Associates Limited | Real estate | 2008 |
| Egton Play Group | Education | 2004 |
| EIJ Ltd | Real estate | 2022 |