| East Coast Sanctuary CIC | Health & social care | 2025 |
| East Farm Holiday Cottages Ltd | Real estate | 2024 |
| Easy Giving Ltd | Financial services | 2023 |
| Easysoft Limited | Information & communication | 1993 |
| EAT and Green Ltd | Professional & scientific | 2019 |
| EB Advanced Limited | Education | 2023 |
| EB Education Services Limited | Education | 2015 |
| EB Esol Limited | Education | 2022 |
| EB Languages Ltd | Education | 2018 |
| EB Maths Ltd | Education | 2018 |
| EB Primary Ltd | Education | 2018 |
| EB Property Limited | Real estate | 2021 |
| EB Science Ltd | Education | 2018 |
| Ebenezer Chapel Management Company Limited | Real estate | 2009 |
| ECAS1 LLP | | 2018 |
| ECAS2 Limited | Information & communication | 2005 |
| Ecco Motors Ltd | Wholesale & retail | 2025 |
| Ecfs Holdings Ltd | Financial services | 2025 |
| Ecfs Plant Hire Ltd | Administrative & support | 2017 |
| Ecfs Plant Sales Ltd | Wholesale & retail | 2019 |
| Ecfs Projects Ltd | Transport & logistics | 2017 |
| Echowell Audiology Wetherby Ltd | Wholesale & retail | 2025 |
| Eclecticism.P.M. Ltd | Professional & scientific | 2021 |
| Eco-Tec Heating Solutions Limited | Manufacturing | 2018 |
| Ecostrad Limited | Wholesale & retail | 2020 |
| Ecoterra Ltd | Professional & scientific | 2025 |
| Ecowise Waste Removal Ltd | Water & waste | 2025 |
| ECS Hub Ltd | Financial services | 2025 |
| Eden Cottage Yarns Ltd | Manufacturing | 2014 |
| Eden Hills Group Ltd | Construction | 2023 |
| Eden Search & Select Limited | Administrative & support | 2010 |
| Edgeway Ltd | Real estate | 2019 |
| EDJ Interiors Limited | Wholesale & retail | 2007 |
| EFM (UK) Limited | Construction | 2009 |
| Eglinton Estates Limited | Real estate | 2005 |
| Egremont Healthcare Limited | Health & social care | 2019 |
| Eiga Ltd | Administrative & support | 2021 |
| EJT Holdings Ltd | Financial services | 2021 |
| Electrical Power Control Solutions Ltd | Construction | 2017 |
| Eleia Limited | Financial services | 2021 |
| Elevenhq Ltd | Information & communication | 2026 |
| Eliveate ME Ltd | Other services | 2025 |
| Elizabeth M Sharp Design + Architecture Ltd | Professional & scientific | 2012 |
| Elizzora Luxury Cruise Collection Limited | Administrative & support | 2026 |
| Ellen Alice Limited | Professional & scientific | 2016 |
| Ellie MAY Beauty Ltd | Other services | 2024 |
| Elliott Charles International Limited | Administrative & support | 2022 |
| Elliott Events Plumbing Limited | Construction | 2025 |
| Elliott's Plumbing, Heating and GAS Limited | Construction | 2025 |
| Ellis Rugby Limited | Wholesale & retail | 2017 |
| Elmwood Green (Apartments) Management Company Ltd | Real estate | 2025 |
| Elmwood Green (Pudsey) Management Company Ltd | Real estate | 2025 |
| Elucity Limited | Professional & scientific | 2018 |
| Elysium Hotel Collection Ltd | Hospitality | 2025 |
| EM Management Services Limited | Real estate | 2022 |
| Em.Ex Management Company Limited | Households | 2026 |
| Emeraldforce Limited | Real estate | 1993 |
| Emergencyman Ltd | Construction | 2019 |
| Emily's Notebook Ltd | Arts & recreation | 2021 |
| Emma Piper Resourcing Limited | Information & communication | 2017 |
| Encon Group Limited | Professional & scientific | 1981 |
| Encon Holdings Limited | Professional & scientific | 1996 |
| Encon Insulation Limited | Construction | 1978 |
| Encon Investments Limited | Professional & scientific | 1997 |
| Encon Limited | Professional & scientific | 1997 |
| Encon Manufacturing Limited | Extraterritorial | 1989 |
| Encon RGS Anglia Limited | Extraterritorial | 1986 |
| Encon RGS London Limited | Extraterritorial | 1988 |
| Encon RGS Scotland Limited | Extraterritorial | 1985 |
| Encon RGS South West Limited | Extraterritorial | 1987 |
| Encon RGS Yorkshire Limited | Extraterritorial | 1985 |
| Encontracts Limited | Extraterritorial | 1990 |
| Encore Services Ltd | Wholesale & retail | 2020 |
| Endv Ltd | Real estate | 2020 |
| ENDV2 Limited | Households | 2021 |
| ENDV3 Limited | Households | 2021 |
| ENDV4 Limited | Households | 2021 |
| ENDV5 Limited | Households | 2021 |
| ENDV6 Limited | Households | 2021 |
| ENDV7 Ltd | Real estate | 2021 |
| Energy Independence Limited | Other services | 2022 |
| Engage Consultancy Limited | Professional & scientific | 2003 |
| Engaging Management Consulting Services Limited | Administrative & support | 2016 |
| Enhanced Control Solutions Ltd | Construction | 2019 |
| Enso Automotive Limited | Wholesale & retail | 2013 |
| Enterprise Services Limited | Wholesale & retail | 1992 |
| Entertainment Worldwide Ltd | Arts & recreation | 2014 |
| EPH Creative Limited | Administrative & support | 2003 |
| Epona Ltd | Health & social care | 2024 |
| Epsilon Partitioning Systems Limited | Extraterritorial | 2001 |
| Equestrian Management Consultants Limited | Information & communication | 1977 |
| Equi Invest Ltd | Wholesale & retail | 2026 |
| Esco Electrical Engineering Ltd | Professional & scientific | 2003 |
| Essence International Search Limited | Administrative & support | 2014 |
| Estate Services (Wetherby) Limited | Administrative & support | 2001 |
| Ethica Recruit Ltd | Professional & scientific | 2019 |
| Evans T Limited | Professional & scientific | 2021 |
| Event Prop Hire Limited | Extraterritorial | 2021 |
| Everatt Properties Limited | Real estate | 2016 |
| Everben Holdings Ltd | Financial services | 2024 |